Anagrelide HCl - 10mM in DMSO , Phosphodiesterase 3 inhibitor, CAS No.58579-51-4, Phosphodiesterase 3 inhibitor

CAS: 58579-51-4 Cat. No.: A408166 Formule: C₁₀H₇Cl₂N₃O·HCl Poids moléculaire: 292.55 Numéro CE: 680-360-9

GRADE & PURITY 10mM in DMSO

Synonyms

BL-4162A | 6,7-dichloroimidazo[2,1-b]quinazolin-2(1H,3H,5H)-one hydrochloride

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Information

Anagrelide HCl Anagrelide (BL-4162A) is a drug used for the treatment of essential thrombocytosis.
In vitro

Anagrelide is an oral imidazoquinazoline agent with an anti-cyclic AMP phosphodiesterase activity and inhibits platelet aggregation in both humans and animals. Anagrelide works by inhibiting the maturation of platelets from megakaryocytes.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonymes

BL-4162A | 6,7-dichloroimidazo[2,1-b]quinazolin-2(1H,3H,5H)-one hydrochloride

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

Anagrelide (BL-4162A) is a drug used for the treatment of essential thrombocytosis.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Mécanisme d'action

Phosphodiesterase 3 inhibitor

Noms et identifiants

• Isomères SMILES: C1C2=C(C=CC(=C2Cl)Cl)N=C3N1CC(=O)N3.Cl
• WGK Allemagne: 3
• Poids moléculaire: 292.55
• Reaxy-Rn: 4614131
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4614131&ln=

Propriétés chimiques et physiques

• Solubilité: Solubility (25°C) In vitro Water: 100 mg/mL DMSO: Insoluble; Ethanol: Insoluble