Apcin-A - ≥98% , CAS No.1683617-62-0

CAS: 1683617-62-0 Cat. No.: A412850 Molecular Weight: 342.61

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

PROTAC

Overview

Apcin-A is an anaphase-promoting complex (APC) inhibitor that interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.

Specifications

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Apcin-A is an anaphase-promoting complex (APC) inhibitor that interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Canonical Smiles: C1=CN=C(N=C1)NC(C(Cl)(Cl)Cl)NC(=O)OCCCN
• IUPAC Name: 3-aminopropyl N-[2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate
• InChIKey: JQTSJVDIFMKETH-UHFFFAOYSA-N
• INCHI: 1S/C10H14Cl3N5O2/c11-10(12,13)7(17-8-15-4-2-5-16-8)18-9(19)20-6-1-3-14/h2,4-5,7H,1,3,6,14H2,(H,18,19)(H,15,16,17)
• Molecular Weight: 342.61
• Reaxy-Rn: 30417124
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30417124&ln=

Chemical and Physical Properties

• Molecular Weight: 342.600 g/mol
• XLogP3: 2.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 341.021 Da
• Monoisotopic Mass: 341.021 Da
• Topological Polar Surface Area: 102.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 297.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1