Aspartame - 10mM in DMSO , CAS No.22839-47-0

CAS: 22839-47-0 Cat. No.: A408096 Formule: C₁₄H₁₈N₂O₅ Poids moléculaire: 294.3 Beilstein Registry Number: 2223850 Numéro CE: 245-261-3

GRADE & PURITY 10mM in DMSO

Synonyms

SC-18862 | (S)-3-amino-4-((S)-1-methoxy-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Information

Aspartame (SC-18862) is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonymes

SC-18862 | (S)-3-amino-4-((S)-1-methoxy-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

Aspartame (SC-18862) is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Propriétés du produit

• ALogP: -2.7

Noms et identifiants

• Isomères SMILES: COC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(=O)O)N
• WGK Allemagne: 2
• RTECS: WM3407000
• Poids moléculaire: 294.3
• Beilstein: 2223850
• Reaxy-Rn: 4707041
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4707041&ln=

Propriétés chimiques et physiques

• Rotation spécifique [α]: 14.5 ° (C=4, 15mol/L Formic Acid)
• Point de fusion (°C): 248-250°C

Références

1. Zhijian Ke, Junyun Song, Jingrui Ma, Mengting Wang, Haiguang Mao, Chunli Xia, Lili Qi, Yidong Zhou, Jinbo Wang.  (2023)  Isolation and characterization of the aspartame-degrading strain Pseudarthrobacter sp. AS-1.  ENVIRONMENTAL POLLUTION,      [PMID:37944888] [10.1016/j.envpol.2023.122883]

2. Jun Dong, Haoran Wu, Yi Cao, Jiaxin Yuan, Qingyan Han, Wei Gao, Chengyun Zhang, Jianxia Qi, Mengtao Sun.  (2022)  Capillary-force-assisted self-assembly of gold nanoparticles into highly ordered plasmonic thin films for ultrasensitive SERS.  PHYSICAL CHEMISTRY CHEMICAL PHYSICS,  25  (3): (1649-1658).  [PMID:36541051] [10.1039/D2CP05158C]

3. Qichao Ye, Chen Men, Lili Tian, Yuxin Liu, Lei Zhan, Yuan Fang Li, Cheng Zhi Huang, Shu Jun Zhen.  (2021)  Preparation of a molecularly imprinted test strip for point-of-care detection of thiodiglycol, a sulfur mustard poisoning metabolic marker.  TALANTA,      [PMID:34364498] [10.1016/j.talanta.2021.122701]

4. Ferry Saputra, Yu-Heng Lai, Rey Arturo T. Fernandez, Allan Patrick G. Macabeo, Hong-Thih Lai, Jong-Chin Huang, Chung-Der Hsiao.  (2021)  Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae.  Biology-Basel,  10  (6): (548).  [PMID:34207293] [10.3390/biology10060548]

5. Sun Xiao-Dong, Wu Hai-Long, Liu Zhi, Chen Yue, Liu Qian, Ding Yu-Jie, Yu Ru-Qin.  (2018)  Rapid and Sensitive Detection of Multi-Class Food Additives in Beverages for Quality Control by Using HPLC-DAD and Chemometrics Methods.  Food Analytical Methods,  12  (2): (381-393).  [PMID:] [10.1007/s12161-018-1370-3]

6. Hongmei Zhang, Shixin Sun, Yanqing Wang, Zhenghao Fei, Jian Cao.  (2018)  Binding mechanism of five typical sweeteners with bovine serum albumin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:30015031] [10.1016/j.saa.2018.07.013]

7. Li’na Qiao, Sihua Qian, Yuhui Wang, Hengwei Lin.  (2018)  A colorimetric sensor array based on sulfuric acid assisted KMnO4 fading for the detection and identification of pesticides.  TALANTA,      [PMID:29426516] [10.1016/j.talanta.2018.01.029]

8. Hongkun Zhao, Chunning Chen, Yalei Wang, Jiaqi Liu, Jiaxin Lu, Jingtong Zhai, Rui Li, Nan Lu.  (2025)  A paper-based SERS/colorimetry substrate for reliable detection.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:39824014] [10.1016/j.saa.2025.125731]

9. Bin Qiu, Zhao Chen, Xiaomei Pei, Zhenggang Cui, Binglei Song.  (2025)  Viscoelastic behavior of wormlike micellar solutions formed by an aspartame-based bicephalous anionic surfactant.  Soft Matter,  21  (8): (1583-1591).  [PMID:39902528] [10.1039/D5SM00013K]

10. Linyang Song, Xiaoyi He, Mengxia Wang, Lixia Li, Jing Liu, Guoying Li, Junhua Yang.  (2023)  IFN-γ mediated neuroinflammation and behaviour abnormality after maternal exposure to low dose mixture of food additives and pesticides.  FOOD AND AGRICULTURAL IMMUNOLOGY,      [PMID:] [10.1080/09540105.2023.2226841]

11. Weiwei Jiang, Yuwei Cheng, Lei Hou, Ying Huang, Sizhen Wang, Yunchang Zhang, Tao Jiang, Feng Yang, Zhiqiang Ma.  (2024)  A dual-prodrug nanogel combining Vorinostat and Pyropheophorbide a for a high efficient photochemotherapy.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:38977163] [10.1016/j.ijpharm.2024.124422]

12. Yan Bai, Ji Feng, Xiao-Yu Wu, Zhi-Sheng Yao, Yue-Tong Liu, Yu-Hong Li, Guo-Dong Lu, Kun Xue.  (2026)  Aspartame exacerbates cerebral ischemia–reperfusion injury via mitochondrial dysfunction and ERK/CREB1 pathway suppression.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:41762991] [10.1016/j.ecoenv.2026.119938]

13. Shiqin Gong, Ziqi Li, Fang Liu, Yi Xiao.  (2026)  Aspartame induces autophagy to extend healthspan in Caenorhabditis elegans via mTORC1/LET-363-TFEB/HLH-30 pathway.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2026.108775]