Beclometasone - Moligand™,≥99% , CAS No.4419-39-0

CAS: 4419-39-0 Cat. No.: B1434492 Molecular Weight: 408.92 EC Number: 224-585-9 PubChem CID: 20469

GRADE & PURITY Moligand™, ≥99%

Synonyms

9-Chloro-11beta,17,21-trihydroxy-16beta-methyl-pregna-1,4-diene-3,20-dione | 9-Chloro-16beta-methylprednisolone | 9alpha-Chloro-16beta-methylprednisolone | Becolvent

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Beclometasone (Beclomethasone) is a prototype glucocorticoid receptor agonist.

Specifications

Synonyms

9-Chloro-11beta, 17, 21-trihydroxy-16beta-methyl-pregna-1, 4-diene-3, 20-dione | 9-Chloro-16beta-methylprednisolone | 9alpha-Chloro-16beta-methylprednisolone | Becolvent

Specifications & Purity

Moligand™, ≥99%

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)Cl)C
• IUPAC Name: (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
• InChIKey: NBMKJKDGKREAPL-DVTGEIKXSA-N
• INCHI: 1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• Isomeric SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)Cl)C
• WGK Germany: 3
• PubChem CID: 20469
• Molecular Weight: 408.92

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Steroids and steroid derivatives
      • Subclass Hydroxysteroids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Steroids and steroid derivatives
• Subclass: Hydroxysteroids
• Intermediate Tree Nodes: Not available
• Direct Parent: 21-hydroxysteroids
• Alternative Parents: Gluco/mineralocorticoids, progestogins and derivatives 20-oxosteroids 11-beta-hydroxysteroids 17-hydroxysteroids 3-oxo delta-1,4-steroids Halogenated steroids Delta-1,4-steroids Tertiary alcohols Alpha-hydroxy ketones Secondary alcohols Cyclic ketones Cyclic alcohols and derivatives Chlorohydrins Alkyl chlorides Hydrocarbon derivatives Organic oxides Organochlorides Primary alcohols
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Progestogin-skeleton - 21-hydroxysteroid - Pregnane-skeleton - 20-oxosteroid - 3-oxo-delta-1,4-steroid - 3-oxosteroid - 17-hydroxysteroid - 11-hydroxysteroid - 11-beta-hydroxysteroid - Oxosteroid - 9-halo-steroid - Halo-steroid - Delta-1,4-steroid - Alpha-hydroxy ketone - Cyclic alcohol - Tertiary alcohol - Chlorohydrin - Cyclic ketone - Secondary alcohol - Halohydrin - Ketone - Primary alcohol - Alcohol - Organic oxide - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Alkyl halide - Organooxygen compound - Organochloride - Organohalogen compound - Alkyl chloride - Aliphatic homopolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone.
• External Descriptors: Pregnane and derivatives [Fig]

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solubility：DMSO
• Sensitivity: Light sensitive

References

1. Hongfei Yang, Liangni Qin, Jiaxu Xiao, Xiaoming Pan, Shiyun Han, Linwei Zhang, Jixiang Liang, Yu Si, Hao Wen, Long Li, Xingyu Wang, Xiaojuan Zhang, Dapeng Peng.  (2025)  Preparation of high-specificity monoclonal antibody based on rational hapten design and development of immunoassay for accurate detection of dexamethasone in milk and animal tissues.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107578]