Biotin-PEG2-azide - ≥98% , CAS No.1910803-72-3

CAS: 1910803-72-3 Cat. No.: B595446 Formule: C₁₆H₂₈N₆O₄S Poids moléculaire: 400.5

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Biotin-PEG2-azide is PEG derivative containing a biotin group and an azide group. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Specifications

Spécifications et pureté

≥98%

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%

Noms et identifiants

• Sourires canoniques: C1C2C(C(S1)CCCCC(=O)NCCOCCOCCN=[N+]=[N-])NC(=O)N2
• IUPAC Name: N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
• InChIKey: OVEZMVONEJMGLZ-UHFFFAOYSA-N
• INCHI: 1S/C16H28N6O4S/c17-22-19-6-8-26-10-9-25-7-5-18-14(23)4-2-1-3-13-15-12(11-27-13)20-16(24)21-15/h12-13,15H,1-11H2,(H,18,23)(H2,20,21,24)
• Poids moléculaire: 400.5
• Reaxy-Rn: 50740936
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=50740936&ln=

Propriétés chimiques et physiques

• Solubilité: Solubility in Water, DMSO, DCM, DMF

Références

1. Jia Mutian, Wang Yuanyuan, Wang Jie, Qin Danhui, Wang Mengge, Chai Li, Fu Yue, Zhao Chunyuan, Gao Chengjiang, Jia Jihui, Zhao Wei.  (2023)  Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.  Nature Communications,  14  (1): (1-12).  [PMID:36750575] [10.1038/s41467-023-36332-3]