CCF0058981 - 10mM in DMSO , CAS No.C661647(DMSO)

CAS: C661647(DMSO) Cat. No.: C661647 Formule: C₂₄H₁₉ClN₆O Poids moléculaire: 442.9

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL pro ) with an IC 50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COV

IC50& Target:IC50: 68 nM (SC2) and 19 nM (SC1)

In Vitro:CCF0058981 (CCF981) has cytopathic effect (CPE) inhibition (EC 50 =497 nM) and plaque reduction (EC 50 =558 nM) in vitro viral replication. CCF0058981 has the 50% cytotoxic concentration (CC 50 ) in the CPE antiviral assay of >50 μM. CCF0058981

Biological Activity:CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL pro ) with an IC 50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COV

Specifications

Spécifications et pureté

10mM in DMSO

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Noms et identifiants

Sourires canoniques

O=C(N(C1=CC=C(C2=CNC=N2)C=C1)CC3=CC=CC(Cl)=C3)CN4N=NC5=CC=CC=C54

Poids moléculaire

442.9