CCK Octapeptide sulfated, Cholecystokinin A receptor agonist, CAS No.25126-32-3, Cholecystokinin A receptor agonist

CAS: 25126-32-3 Cat. No.: C276294 Molecular Weight: 1143.3

GRADE & PURITY Moligand™, ≥97%

Overview

Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.

Specifications

Product Name

CCK Octapeptide sulfated, Cholecystokinin A receptor agonist, CAS No.25126-32-3

Synonyms

L-alpha-Aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide | NCGC00016495-01 | CORALYNECHLORIDEHYDRATE, 98+% | E78048 | GTPL864 | Sincalidum | Sincalidum [INN-Latin] | UNII-M03GIQ7Z6P | DB09142 | DTXS

Grade

Moligand™

Specifications & Purity

Moligand™, ≥97%

Biochemical and Physiological Mechanisms

Endogenous C-terminal octapeptide of CCK involved in the neurobiology of anxiety, depression, psychosis, cognition, nociception and feeding behavior.

Sequence

H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2

Action Type

AGONIST

Mechanism of action

Cholecystokinin A receptor agonist

Note

This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

CAS

25126-32-3

Molecule Type

Protein

Product Properties

• ALogP: -2.6

Storage and Shipping

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Phenylalanine and derivatives Aspartic acid and derivatives Methionine and derivatives N-acyl-alpha amino acids and derivatives Tryptamines and derivatives Alpha amino acid amides Phenylsulfates Amphetamines and derivatives 3-alkylindoles Phenoxy compounds Sulfuric acid monoesters Substituted pyrroles Dicarboxylic acids and derivatives N-acyl amines Heteroaromatic compounds Primary carboxylic acid amides Secondary carboxylic acid amides Amino acids Azacyclic compounds Dialkylthioethers Carboxylic acids Sulfenyl compounds Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Alpha-oligopeptide - Phenylalanine or derivatives - Methionine or derivatives - Aspartic acid or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Triptan - Phenylsulfate - N-substituted-alpha-amino acid - Arylsulfate - Amphetamine or derivatives - Alpha-amino acid or derivatives - 3-alkylindole - Indole or derivatives - Indole - Phenoxy compound - Monocyclic benzene moiety - Dicarboxylic acid or derivatives - Substituted pyrrole - Fatty acyl - Benzenoid - Fatty amide - Sulfuric acid ester - N-acyl-amine - Sulfate-ester - Sulfuric acid monoester - Pyrrole - Organic sulfuric acid or derivatives - Heteroaromatic compound - Amino acid or derivatives - Amino acid - Carboxamide group - Secondary carboxylic acid amide - Primary carboxylic acid amide - Carboxylic acid - Thioether - Sulfenyl compound - Azacycle - Dialkylthioether - Organoheterocyclic compound - Primary amine - Primary aliphatic amine - Hydrocarbon derivative - Amine - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Organic oxide - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CCKAR Tclin Cholecystokinin receptor type A (0 Activities)

Discover Target: CCKAR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCKBR Tclin Gastrin/cholecystokinin type B receptor (0 Activities)

Discover Target: CCKBR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCKBR Tclin Cholecystokinin B receptor (3550 Activities)

Discover Target: CCKBR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

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Jurkat (10389 Activities)

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 Activities)

Discover Target: SLCO2B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Cckar Cholecystokinin A receptor (90 Activities)

Discover Target: Cckar

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cavia porcellus (23802 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Oryctolagus cuniculus (11301 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Rattus norvegicus (775804 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slco1b2 Solute carrier organic anion transporter family member 1B2 (36 Activities)

Discover Target: Slco1b2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Genetic information

• Alternate Names: L-alpha-Aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide | NCGC00016495-01 | CORALYNECHLORIDEHYDRATE,98+% | E78048 | GTPL864 | Sincalidum | Sincalidum [INN-Latin] | UNII-M03GIQ7Z6P | DB09142 | DTXS
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13. Qi Lei, Dengfeng He, Liangping Ding, Fanhui Kong, Peiying He, Junda Huang, Jimin Guo, C. Jeffrey Brinker, Gaoxing Luo, Wei Zhu, Yunlong Yu.  (2022)  Microneedle Patches Integrated with Biomineralized Melanin Nanoparticles for Simultaneous Skin Tumor Photothermal Therapy and Wound Healing.  ADVANCED FUNCTIONAL MATERIALS,  32  (22): (2113269).  [PMID:] [10.1002/adfm.202113269]

14. Jing-Yu Duan, Wei Chen, Yang-Qi Zhao, Liang-Liang He, En-Chao Li, Zhong-Hui Bai, Yong-Jian Wang, Chun-Ping Zhang.  (2021)  Flavonoids from Hypericum patulum enhance glucose consumption and attenuate lipid accumulation in HepG2 cells.  JOURNAL OF FOOD BIOCHEMISTRY,  45  (9): (e13898).  [PMID:34378802] [10.1111/jfbc.13898]

15. Caizhen Liang, Xiaobao Xie, Dandan Zhang, Jin Feng, Shunying Lu, Qingshan Shi.  (2021)  Biomass carbon dots derived from Wedelia trilobata for the direct detection of glutathione and their imaging application in living cells.  Journal of Materials Chemistry B,  9  (28): (5670-5681).  [PMID:34195715] [10.1039/D0TB02979C]

16. Hongbin Li, Xinjing Wei, Xiaotong Yi, Shize Tang, Jinmei He, Yudong Huang, Feng Cheng.  (2021)  Antibacterial, hemostasis, adhesive, self-healing polysaccharides-based composite hydrogel wound dressing for the prevention and treatment of postoperative adhesion.  Materials Science & Engineering C-Materials for Biological Applications,      [PMID:33812606] [10.1016/j.msec.2021.111978]

17. Xingxing Ni, Yujie Gao, Xinhai Zhang, Yang Lei, Gang Sun, Bo You.  (2020)  An eco-friendly smart self-healing coating with NIR and pH dual-responsive superhydrophobic properties based on biomimetic stimuli-responsive mesoporous polydopamine microspheres.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2020.126725]

18. Dandan Xu, Yong Li, Naixin Li, Fang Lei, Jinliang Liu, Ying Shi, Luqiao Yin, Lei Zhang.  (2020)  A facile synthesis of CDs from quinoa for nanosensors and bio-imagining.  Nano Express,  1  (2): (020001).  [PMID:] [10.1088/2632-959X/ab9f53]

19. Xue Gao, Zhe Yu, Bingxin Liu, Jixu Yang, Xiaoyan Yang, Yueqin Yu.  (2020)  A smart drug delivery system responsive to pH/enzyme stimuli based on hydrophobic modified sodium alginate.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2020.109779]

20. Yang Hainan, Liu Zaijia, Li Xufeng, Zhang Zhenfeng, Chen Deji, Lian Hui.  (2018)  Artesunate-Loaded and Near-Infrared Dye-Conjugated Albumin Nanoparticles as High-Efficiency Tumor-Targeted Photo-Chemo Theranostic Agent.  Nanoscale Research Letters,  13  (1): (1-10).  [PMID:30311065] [10.1186/s11671-018-2700-5]

21. Lijia Wang, Ying Cai, Zhengbin An, Wenhong Gu, Ping Chen, Qingyun Cai.  (2018)  ZnO-functionalized mesoporous inner-empty nanotheranostic platform: upconversion imaging guided chemotherapy with pH-triggered drug delivery.  NANOTECHNOLOGY,  29  (50): (505101).  [PMID:30207290] [10.1088/1361-6528/aae0b6]

22. Huan Tan, Zhao Tu, Hongqian Jia, Xiaojun Gou, To Ngai.  (2018)  Hierarchical Porous Protein Scaffold Templated from High Internal Phase Emulsion Costabilized by Gelatin and Gelatin Nanoparticles.  LANGMUIR,      [PMID:29631405] [10.1021/acs.langmuir.7b04047]

23. Sun Xin-Ran, Yuan Hao-Ming, Zhang Guo-Da, Wang Chao, Sun Shu-Juan, Shi Peng-Fei.  (2024)  A Mn-porphyrinic metal–organic framework immobilizing glucose oxidase for combined photodynamic/chemodynamic/starvation therapy.  Tungsten,      [PMID:] [10.1007/s42864-024-00283-z]

24. Aili Wang, Xi Ruan, Xuejiao Wang, Yuyu Ren, Chunjiao Shen, Kaiyi Zhang, Zhenjie Song, Bai Xiang, Yinling Ma, Feng Zhao.  (2024)  A one-stop integrated natural antimicrobial microneedles with anti-inflammatory, pro-angiogenic and long-term moisturizing properties to accelerate diabetic wound healing.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:39134098] [10.1016/j.ejpb.2024.114448]

25. Yan Fang, Yicheng Zhang, Liping Qiu, Yuxia Zhang, Siqi Chen, Yunxiang Weng, Haiqing Liu, Qinhui Chen.  (2024)  Amphiphilic Janus cotton gauze with enhanced moisture management and blood coagulation for rapid hemostasis and wound healing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39002908] [10.1016/j.ijbiomac.2024.133826]

26. Liu Guo, Fang Yu, Li Jiamiao, Chen Zhaofei.  (2025)  Anoikis-related PLCB4 is linked to immunotherapy response in osteosarcoma.  Discover Oncology,  16  (1): (1-13).  [PMID:39987366] [10.1007/s12672-025-01970-0]

27. Jun-qi Zhan, Jun-xin Wu, Jing-jing Fu, Gao-shang Li, Fang Wu, Yue-wen Chen.  (2024)  Antioxidant synergistic anti-inflammatory effect in the MAPK/NF-κB pathway of peptide KGEYNK (KK-6) from giant salamander (Andrias davidianus).  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,      [PMID:38953326] [10.1002/jsfa.13689]

28. Chen Jie, Feng Chengyu, Lan Yufei, Chen Xiangtian, Peng Zhengqi, Huang Zihan, Wang Ruiqing, Zhang Wenxin, Ye Yingying, Mao Zhilei, Pan Dongyue, Yang Lihua.  (2025)  Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-19).  [PMID:39923065] [10.1186/s12951-025-03177-5]

29. Jiale Chen, Pan Ran, Yizhao Xu, Mouna Khouchani, Xin Li, Ling Jian, Takoui Abdelmajid, Nadia Aittahssaint, Qian Yang, Jingyi Li, Long Zhao.  (2025)  Biomimetic multifunctional nanoparticles for improved radiotherapy and immunotherapy in cancer treatment.  Materials Today Bio,      [PMID:40225127] [10.1016/j.mtbio.2025.101698]

30. Jing Yang, Yong Yuan, Jiongrui Hou, Zhiyong Xu, Yu Du, Jingqin Yang, Shaoyun Shan, Tianding Hu, Chengxiao Wang, Hongying Su.  (2024)  Cyclodextrin metal–organic framework derived nano-cubic gel particles for the efficient removal of bilirubin.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.131071]

31. Yan Luo, Tengxiang Wang, Ke Yang, Taixiang Liu, Xue Bai.  (2024)  Electrospun borneol/PVP antibacterial coating for postoperative management of keratoprosthesis implantation.  MATERIALS TECHNOLOGY,      [PMID:] [10.1080/10667857.2024.2309596]

32. Jianbo Wu, Minggang Yang, Yibo Huang, Yuan Zhang, Ben Wu, Shi Qiu, Feiyang Hong, Ye Gao, Zhuo Wang, Guocheng Wang.  (2024)  Enhancing the Biological Performance of Titanium Alloy through In Situ Modulation of the Surface Nanostructure: Near-Infrared-Responsive Antibacterial Function and Osteoinductivity.  ACS Applied Bio Materials,      [PMID:38840339] [10.1021/acsabm.4c00244]

33. Deng Chunmin, Zhang Hao, Song Li.  (2024)  Environment-responsive dopamine nanoplatform for tumor synergistic therapy.  Discover Oncology,  15  (1): (1-13).  [PMID:39101970] [10.1007/s12672-024-01214-7]

34. Qing Luo, Chenyue Yan, Ruoteng Ma, Lei Dai, Wenjun Shu, Anum Asghar, Zhigang Jia, Xulong Zhu, Shun Yu.  (2025)  E-PL/MnO2 nanozymes/gellan gum/hyaluronic acid-based multifunctional hydrogel to promote diabetic wound healing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39924029] [10.1016/j.ijbiomac.2025.140777]

35. Sheng Li, Wentong Fan, Qiulin Chen, Xinfeng Zhang.  (2024)  Facile Light-Driven Synthesis of Highly Luminous Sulfur Quantum Dots for Fluorescence Sensing and Cell Imaging.  ACS Applied Materials & Interfaces,      [PMID:39074383] [10.1021/acsami.4c05739]

36. Minggang Yang, Yufan Zhang, Zhenhao Hou, Jianbo Wu, Fuwei Liu, Jun Wu, Kelvin W.K. Yeung, Wenhao Qian, Xuanyong Liu, Liang Kong, Yunpeng Li, Jiajun Qiu, Guocheng Wang.  (2025)  NIR-I Light-Activated Antibiotic Delivery & PDT via TiO2/Graphene Metastructure for Enhanced Antibacterial Activity and Osseointegration of Ti Implants.  Advanced Healthcare Materials,      [PMID:40145804] [10.1002/adhm.202500743]

37. Hao Liu, Ke Huang, Hao Zhang, Xiaohui Liu, Hui Jiang, Xuemei Wang.  (2024)  Photo-Driven In Situ Solidification of Whole Cells through Inhibition of Trogocytosis for Immunotherapy.  Research,      [PMID:38384327] [10.34133/research.0318]

38. Yuefang Hu, Yuxin Chen, Wenwang Wei, Hanfu Liu.  (2024)  Preparation of biomass-derived red emission carbon dots for real-time and long-term tracking of cells and tumor growth.  RSC Advances,  14  (50): (37104-37113).  [PMID:39569107] [10.1039/D4RA05018E]

39. Liu Lu, Zhao Xuefen.  (2024)  Preparation of environmentally responsive PDA&DOX@LAC live drug carrier for synergistic tumor therapy.  Scientific Reports,  14  (1): (1-16).  [PMID:38987493] [10.1038/s41598-024-66966-2]

40. Yu Du, Yaqi Xu, Jiongrui Hou, Xueling Li, Jing Yang, Jingqin Yang, Shaoyun Shan, Chengxiao Wang, Hongying Su.  (2025)  Robust fabrication of pyrogallol-conjugated dextran hydrogel as antioxidant hemo-adsorbent for the selective adsorption of Pb(II).  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.132098]

41. Kang Wei, Yiran Shi, Min Wang, Lu He, Huanhuan Xu, Haijie Wang, Langjie Chai, Ling Zhou, Yi Zou, Liang Guo.  (2025)  Schwann cells secrete IGFBP5 to facilitate the growth of keloids.  LIFE SCIENCES,      [PMID:40049369] [10.1016/j.lfs.2025.123534]

42. Niu Junjie, Hu Jinyang, Wang Zhu.  (2024)  Scutellaria barbata D.Don extract regulates Ezrin-mediated triple negative breast cancer progress via suppressing the RhoA /ROCK1 signaling.  Toxicology Research,  13  (2):   [PMID:38525246] [10.1093/toxres/tfae033]

43. Fang Chen, Run Guo, Tian Chen, Liping Liu, Fan Ding, Gang Zhao, Bo Zhang.  (2025)  The Therapeutic Potential of Low-Intensity Pulsed Ultrasound in Enhancing Gallbladder Function and Reducing Inflammation in Cholesterol Gallstone Disease.  Bioengineering-Basel,  12  (1): (34).  [PMID:39851308] [10.3390/bioengineering12010034]

44. Haihua Zhou, Hongyan Pan, Faisal Raza, Hajra Zafar, Yu Ge, Nan Wang, Ronglei Zheng, Degeng Zhang, Yanmin Yang.  (2024)  Thermosensitive drug-loaded liposomes for photothermal and chemotherapeutic treatment of colon cancer.  Materials Advances,  5  (6): (2456-2469).  [PMID:] [10.1039/D3MA01060K]

45. Tang Yu, Xian Zhengping, Wu Fengjiao, Cao Hongyu, Wang Lihao, Tang Qian, Du Yanan, Zheng Xuefang.  (2024)  Traditional Chinese medicine combined with chemotherapy in the treatment of advanced non-small cell lung cancer: key drug screening and mechanism analysis.  NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY,      [PMID:39073415] [10.1007/s00210-024-03310-5]

46. Shakila Baby, Muruganantham Bharathi, Sukumar Kalpana, Hirad Abdurahman Hajinur, Alarfaj Abdullah A., Hussein-Al-Ali Samer Hasan, Surya Parthasarathy.  (2024)  Tri-Responsive Drug Delivery System for Lung Cancer Treatment: Enhanced Photothermal Conversion and Targeted Apoptosis in H1299 Cells.  Journal of Medical and Biological Engineering,      [PMID:] [10.1007/s40846-024-00913-4]

47. Chuanjuan Chen, Yicheng Zhang, Siqi Chen, Qinhui Chen.  (2025)  Unilateral thermosensitive Janus hemostatic dressing for matching coagulation physiological processes.  Journal of Materials Chemistry B,      [PMID:40201946] [10.1039/D4TB02871F]

48. Jixia Deng, Wenhua Yu, Lei Zhan, Xueying Zhu, Yuanyuan Fang, Pengcheng Zhang, Qinfei Ke, Chen Huang.  (2024)  Wettability regulation of membranes based on biodegradable aliphatic polyester.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2024.123199]

49. Ke Wang, Xiaomin Xia, Nan Wang, Jie Liu, Xue Li.  (2025)  Novel nanocomposites eliminate excess macrophage extracellular traps for anti-inflammatory therapy by scavenging ROS and inducing macrophages polarizing to M2 type.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40695426] [10.1016/j.bcp.2025.117169]

50. Zhongcheng Zhu, Xiaolin Dou, Qizhen Chen, Yebin Lu.  (2025)  Knockdown of Nr4a3 mitigates acute pancreatitis-induced injury by modulating Btg2 to reduce oxidative stress, mitochondrial damage, and apoptosis.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:40706207] [10.1016/j.intimp.2025.115269]

51. Lin-Fang Tan, Xiao-Lin Hou, Xiao-Ting Xie, Meng Guan, Meng-Wen Ma, Fang Zhang, Jin-Xuan Fan, Bo Liu, Yuan-Di Zhao, Qiu-Ran Xu.  (2025)  Electric-Field-Mediated In Situ Electrocatalysis for Enhanced Chemodynamic Therapy and Immunotherapy via 3D Electrode Arrays.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202514805]

52. Meng Yang, Weizhuang Chen, Junru Zhou, Fangxia Guan, Ruimei Jin.  (2025)  “Top-down and Bottom-up” cholesterol-depleting biomimetic nanoparticle for enhancing sonodynamic therapy against hepatocellular carcinoma.  Materials Today Bio,      [PMID:41104047] [10.1016/j.mtbio.2025.102370]

53. Jiaxin Wang, Jinlong Tian, Qilin Tian, Dongnan Li, Ningxuan Gao, Xuefeng Yang, Liang Wang, Ying He, Bin Li, Li Wang.  (2025)  Metabolomic insights into antioxidant properties of blueberry (Vaccinium croymbosum) leaves and a preliminary exploration of their in vitro lipid-lowering activity.  FOOD CHEMISTRY,      [PMID:40934773] [10.1016/j.foodchem.2025.146200]

54. Kang wei, Lu He, Xuan Li, Meng Wu, Haijie Wang, Liangcong Hu, Huanhuan Xu, Yixuan Zhang, Ling Zhou, Xiaojuan Xu, Liang Guo.  (2025)  The β-glucan from Lentinus alleviates UVB-induced dermal fibroblasts senescence and skin photoaging.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40987357] [10.1016/j.ijbiomac.2025.147834]

55. Jintao Wu, Zhaolan Yan, Peng Shan, Wei Li, Kun Wang, Hui Li.  (2025)  Characterization of gelatin-based composite films loaded with polysaccharide and carbon dots from Stropharia rugosoannulata and their application in pork fresh-keeping.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39798742] [10.1016/j.ijbiomac.2025.139702]

56. Huihui Li, Shunchang Wang, Jin Chen, Mengchu Sun, Hongjin Tang.  (2025)  Preparation and characterization of thymol-loaded ZIF-8/κ-carrangeenan/Zein composite film as active food packaging with enhanced functional properties for blueberry preservation.  CARBOHYDRATE POLYMERS,      [PMID:40049976] [10.1016/j.carbpol.2025.123406]

57. Yanping Wang, Peiyan Qi, Shenbao Shi, Cong Pang, Weijie Wang, Dazhao Fang.  (2025)  Targeted therapy for glioblastoma utilizing hyaluronic acid-engineered liposomes for adriamycin delivery.  NANOTECHNOLOGY,  36  (12): (125102).  [PMID:39842037] [10.1088/1361-6528/adacef]

58. Xiao Li, Xingru Lu, Ming Liu, Yu Zhang, Yujun Jiang, Xinyan Yang, Chaoxin Man.  (2024)  The Immunomodulatory Effects of A2 β-Casein on Immunosuppressed Mice by Regulating Immune Responses and the Gut Microbiota.  Nutrients,  16  (4): (519).  [PMID:38398845] [10.3390/nu16040519]

59. Ye Yuan, Yuan Liu, Zhipeng Shen, Huidan Wu, Lantian Meng, Xiaoxiao Guo, Bing Jiang, Ling Fang.  (2025)  Ultrafast synthesis of L-His-Fe3O4 nanozymes with enhanced peroxidase-like activity for effective antibacterial applications.  Frontiers in Bioengineering and Biotechnology,      [PMID:40225120] [10.3389/fbioe.2025.1548025]

60. Zhang Jie, Zhou Huiqian, Hao Tingting, Li Jinyun, Ye Meng, Gao Wanlei, Xie Jianjun, Zhang Qingqing, Guo Zhiyong.  (2025)  Pangolin-type fluorescence imaging of circulating tumor cell based on functionalized 2D nanomaterial.  MICROCHIMICA ACTA,  192  (8): (1-10).  [PMID:40719943] [10.1007/s00604-025-07406-4]

61. Wanting Xue, Weihan Zheng, Huihui Zhang, Jiaxin Yang, Wenfeng Deng, Zhenning Dai, Ke Liu, Yunyun Chen, Xinyi Yun, Jiaying Li, Shiyu Li, Wenhua Huang.  (2025)  Dual-Targeted Metabolic Nanovesicles Reprogram Macrophage-Cardiomyocyte Crosstalk for Myocardial Ischemia-Reperfusion Therapy.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202507784]

62. He Zhenhong, Zeng Shengqiang, Qin Bo, Liu Gang, Liu Huan, Bao Dingsu.  (2025)  Investigation on the role of Icariin in tendon injury repair: focusing on tendon stem cell differentiation.  Journal of Orthopaedic Surgery and Research,  20  (1): (1-12).  [PMID:40234966] [10.1186/s13018-025-05784-2]

63. Ningcheng Wei, Yi Xiao, Yang Jin, Liying Zhang, Panpan Chen, Shuhu Du.  (2025)  Thioether-bridged carbon dots-dopamine quinone conjugate probe for glutathione sensing and discrimination between glioblastoma and normal cells.  TALANTA,      [PMID:40334510] [10.1016/j.talanta.2025.128249]

64. Chen Mengxia, Liu Ting, Wang Xiaonan, Gao Lizeng, Cheng Yunqing, Jiang Jing, Zhang Jinhua.  (2025)  Comprehensive wound healing using ETN@Fe7S8 complex by positively regulating multiple programmed phases.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-18).  [PMID:40355866] [10.1186/s12951-025-03396-w]

65. Bricard Mbituyimana, Longjun Luo, Fuyu Qi, Yuchi Jiang, Omar Mohammad Atta, Mohamed S. Kishta, Mostafa Maboruk, Min Wu, Wei Ge, Zhijun Shi, Guang Yang.  (2025)  Tree thorns-inspired hyaluronic acid-based dissolving microneedles loaded with salvianolic acid B for effective hypertrophic scar treatment with enhanced long-term stability.  CARBOHYDRATE POLYMERS,      [PMID:40484597] [10.1016/j.carbpol.2025.123773]

66. Xin Yang, Canhui Hong, Tangfei Guan, Chenggui Zhang, Yongshou Yang, Peiyun Xiao, Huai Xiao, Zhengchun He.  (2025)  Periplaneta americana (L.) Extract PAS840 Promotes Ischemic Stroke Recovery by Inhibiting Inflammasome Activation.  Biology-Basel,  14  (6): (589).  [PMID:40563841] [10.3390/biology14060589]

67. Jingyi Dang, Zhao Zhang, Jun Fu, Liguo Sun, Yubo Shi, Lei Wang, Weidong Tao, Debin Cheng, Xiaohe Wang, Zhenzhou Mi, Dong Liu, Hongbin Fan.  (2025)  Regulating inflammation microenvironment and tenogenic differentiation as sequential therapy promotes tendon healing in diabetic rats.  Journal of Orthopaedic Translation,      [PMID:40529900] [10.1016/j.jot.2025.04.015]

68. Shang Xiaofei, Shao Wenjie, Dong Wuqi, Ren Wenxia, Du Wei, Li Chuang, Tian Yuxiang, Fang Weijun, Liu Tao, Xu Qinghua, Zhang Zhongping, Zhao Tingting.  (2025)  Rational engineering of nanoplatforms with hierarchical targeting hepatic tumor and subcellular mitochondria for enhanced image-guided photodynamic therapy.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-22).  [PMID:41074184] [10.1186/s12951-025-03733-z]

69. Mingbo Wu, Dong Li, Yao Liu, Xin Li, Xiaomiao Ruan, Jingwen Yang, Zegang Li, Siyi Chen, Xin Yang, Wenwu Ling.  (2025)  Ultrasound-Activated Fe-Doped Hollow BaTiO3 Nanoparticles for Targeted Venous Thrombolysis Via Piezo-Amplified Fenton Catalysis.  Small,      [PMID:41065172] [10.1002/smll.202505940]

70. Liping Liu, Xinhai Mo, Run Guo, Fang Chen, Fan Ding, Gang Zhao, Bo Zhang.  (2025)  LIPUS Enhances Gallbladder Motility via ANO1 in Acute Cholecystitis Guinea Pigs.  Bioengineering-Basel,  12  (11): (1164).  [PMID:41301120] [10.3390/bioengineering12111164]

71. Yi Zhu, Bo Peng, Ze Zheng, Houli Jiang, Zongtao Ling, Mingzhe Yang, Tingzhao Li, Bo Li, Jun Luo.  (2025)  Molecular networking guided discovery of non-limonoids type ingredients from Citrus medica var. Sarcodactylis fruits.  FITOTERAPIA,      [PMID:41270991] [10.1016/j.fitote.2025.107001]

72. Xinyu Miao, Xiawei Xu, Li Sun, Xiaoxia Wu, Aochi Liu, Pan Fu, Pengtao Chen, Yujiao Xie, Jiabao Guo, Zhiwei Hou, Dong Xu, Aiguo Wu, Jie Lin.  (2025)  Spatiotemporal Identification of Therapeutic Markers via Dual-targeted SERS Bioprobes During Breast Cancer Progression.  Materials Chemistry Frontiers,      [PMID:] [10.1039/D5QM00808E]

73. Long Xu, Yitong Chen, Yao Hu, Cong Wang, Yabin Zhu, Mingxin Dong.  (2025)  Engineering Reactive Oxygen Species-Responsive Supramolecular Gels with Inherent Antibacterial Activity for Combating Bacterial Infections.  LANGMUIR,      [PMID:41400305] [10.1021/acs.langmuir.5c05108]

74. Xudong Duan, Kai Nan, Xiaolong Shao, Yidian Wang, Xincun Qiao, Weisong Zhang, Peng Yang, Shouye Hu, Zhi Yang.  (2026)  Diselenide-engineered peptide nanofibers as single-component supramolecular nanomedicines for osteoarthritis therapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.173442]

75. Mengchu Sun, Chenglong Zhang, Xichao Yin, Hongjin Tang.  (2026)  Fabrication and characterization of ethyl cellulose/Zein-based multifunctional composite film integrated with cinnamaldehyde-loaded Mg-gallic acid-MOF for pork preservation.  FOOD RESEARCH INTERNATIONAL,      [PMID:41794537] [10.1016/j.foodres.2026.118548]

76. Jinqiang Zhu, Wenjun Qin, Bo Wu, Haining Li, Cui Cheng, Xiao Han, Xiwen Jiang.  (2026)  A Conductive, Photothermal and Antioxidant ε-Poly-L-Lysine/Carbon Nanotube Hydrogel as a Candidate Dressing for Chronic Diabetic Wounds.  Polymers,  18  (3): (332).  [PMID:41682040] [10.3390/polym18030332]

77. Zhenyu Wen, Qiping Huang, Qian Du, Qinghong Fan, Qianyu Xie, Yuanhao Lv, Jun Chen, Weikang Xu, Qingde Wa.  (2026)  Polydopamine-Functionalized HMS/PLGA Composite Microsphere Scaffold Modulates Enhances Immunomodulation and Bone Repair.  ACS Biomaterials Science & Engineering,      [PMID:41653118] [10.1021/acsbiomaterials.5c01776]

78. Mengnan Liu, Zhilong Zhou, Heqi Gao, Jiangfei Li, Jiayu Wang, Haitian Zhao, Zhongjun Cheng, Weihong Lu.  (2026)  Enhanced stability in antibacterial performance of thymol/polylactic acid films through grafting “liquid-like” PDMS brushes.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.174692]

79. Huihui Li, Shunchang Wang, Chenglong Zhang, Zhendong Long, Xichao Yin, Hongjin Tang.  (2026)  Nanoconfinement-assisted interfacial engineering for reliable intelligent κ-carrageenan/Zein films.  Innovative Food Science & Emerging Technologies,      [PMID:] [10.1016/j.ifset.2026.104553]

80. Wan Li, Tianxu Gui, Yaqin Hou.  (2026)  Development of a RiskScore model related to cancer-associated fibroblasts for assessing patient prognosis and drug sensitivity in lung adenocarcinoma.  Letters in Drug Design & Discovery,      [PMID:] [10.1016/j.lddd.2026.100333]