Chlorothiazide - Moligand™, 10mM in DMSO , Inhibitor of Na-Cl symporter, CAS No.58-94-6, Inhibitor of Na-Cl symporter

CAS: 58-94-6 Cat. No.: C408191 Molecular Weight: 373.44 EC Number: 200-404-9
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
6-​chloro-​1,​1-​dioxide-2H-​1,​2,​4-​benzothiadiazine-​7-​sulfonamide
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
C408191-1ml
2

$106.90

$154.90
Save $48.00 (30.99%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥98%

Specifications

Synonyms
6-​chloro-​1, ​1-​dioxide-2H-​1, ​2, ​4-​benzothiadiazine-​7-​sulfonamide
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Inhibitor of Na-Cl symporter
Names and Identifiers
Isomeric SMILES C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2
Molecular Weight 373.44
Reaxy-Rn 1084805
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1084805&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
SLC12A3 Tclin Solute carrier family 12 member 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Documents & Articles
Citations of This Product
References
1. Hongying Liu, Cairui Zhang, Chenwei Wang, Kai Fan, Yuqing Zhang, Lu Fang, Lihua Li, Chaoxiang Ren, Zheng-Zhi Yin, Zhong Lü.  (2023)  A highly selective and sensitive sensor for promethazine based on molecularly imprinted interface coated Au/Sn bimetal nanoclusters functionalized acupuncture needle microelectrode.  ANALYTICA CHIMICA ACTA,      [PMID:37290856] [10.1016/j.aca.2023.341395]
Solution Calculators
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