Clofibrate - Moligand™, 10mM in DMSO , Peroxisome proliferator-activated receptor alpha agonist, CAS No.637-07-0, Peroxisome proliferator-activated receptor alpha agonist

CAS: 637-07-0 Cat. No.: C408591 Formule: C₁₂H₁₅ClO₃ Poids moléculaire: 242.7 Beilstein Registry Number: 1913459 Numéro CE: 211-277-4

GRADE & PURITY Moligand™, 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Information

Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Spécifications et pureté

Moligand™, 10mM in DMSO

Mécanismes biochimiques et physiologiques

Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. Clofibrate increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipop

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

AGONIST

Mécanisme d'action

Peroxisome proliferator-activated receptor alpha agonist

Propriétés du produit

• ALogP: 3.3

Noms et identifiants

• Isomères SMILES: CCOC(=O)C(C)(C)OC1=CC=C(C=C1)Cl
• WGK Allemagne: 3
• RTECS: UE9480000
• Numéro ONU: 3082
• Poids moléculaire: 242.7
• Beilstein: 1913459
• Reaxy-Rn: 1913459
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1913459&ln=

Cibles associées (humaines)

PPARA Tclin Peroxisome proliferator-activated receptor alpha (1 Activities)

Discover Target: PPARA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propriétés chimiques et physiques

• Indice de réfraction: 1.503
• Point d'éclair (°F): 235.4 °F - closed cup
• Point d'éclair (°C): 113 °C - closed cup
• Point d'ébullition (°C): 150 °C

Références

1. Cancan Duan, Weina Cheng, Qihong Chen, Xiaofei Li, Jianyong Zhang.  (2021)  Pharmacokinetics and tissue distribution of cantharidin after oral administration of aqueous extracts from Mylabris in rats.  BIOMEDICAL CHROMATOGRAPHY,  35  (10): (e5172).  [PMID:33982312] [10.1002/bmc.5172]

2. Ruijie Xie, Kaiheng Guo, Zhimin Ao, Ziyi Suo, Haibao Huang, DYC Leung.  (2023)  Surface-bound radicals generated from cobalt single-atom catalyst: Mechanism of boosting Fenton-like reactions.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.141920]

3. Hui Sun, Jianzhong Du.  (2018)  Plasmonic vesicles with tailored collective properties.  Nanoscale,  10  (36): (17354-17361).  [PMID:30198031] [10.1039/C8NR04820G]

Foire aux questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 637-07-0, the molecular formula is C12H15ClO3, and the molecular weight is 242.7 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.