COG 133 TFA - ≥98% , CAS No.C658607

CAS: C658607 Cat. No.: C658607 Formule: C₉₉H₁₈₂F₃N₃₇O₂₁ Poids moléculaire: 2283.78

QUALITÉ & PURETÉ ≥98%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC 50 of 4

Appearance:Solid

IC50& Target:IC50: 445 nM (nAChR)

In Vivo:COG 133 (1mg/kg; intratracheal administration; every other day; for 4 weeks) treatment impairs the resolution of pulmonary fibrosis in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model

Biological Activity:COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC 50 of 4

Spécifications

Spécifications et pureté

≥98%

Conditions de stockage de stockage

Desiccated,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

ANTAGONIST

Pureté

≥98%

Noms et identifiants

Poids moléculaire

2283.78

Propriétés chimiques et physiques

• Solubilité: H2O : 50 mg/mL (21.89 mM; Need ultrasonic)