Corylin - 10mM in DMSO , CAS No.53947-92-5

CAS: 53947-92-5 Cat. No.: C424609 Formule: C₂₀H₁₆O₄ Poids moléculaire: 320.34

GRADE & PURITY 10mM in DMSO

Synonyms

CCG-267706 | AKOS032948696 | MFCD20260784 | BDBM50349976 | SCHEMBL1096083 | 3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-4H-1-benzopyran-4-one | 3-(2,2-dimethylchromen-6-yl)-7-hydroxychromen-4-one | DTXSID601156014 | A870604 | MS-24730 | Corylin | s929

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Corylin has antioxidant activity. Corylin may stimulate bone formation or have potential activity against osteoporosis. Corylin shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells.

Specifications

Synonymes

CCG-267706 | AKOS032948696 | MFCD20260784 | BDBM50349976 | SCHEMBL1096083 | 3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-4H-1-benzopyran-4-one | 3-(2,2-dimethylchromen-6-yl)-7-hydroxychromen-4-one | DTXSID601156014 | A870604 | MS-24730 | Corylin | s929

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

Corylin is a flavonoid isolated from fruit and seed of medical herb Psoralea corylifolia that extend the replicative lifespan in yeast by targeting the Gtr1 protein. Also, Corylin extends lifespan in mice fed a high-fat diet. Corylin exhibits numerous pha

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Propriétés du produit

• ALogP: 3.412
• hba_count: 3
• Nombre de HBD: 1
• Liaison rotative: 1

Noms et identifiants

• Pubchem Sid: 528763940
• Sourires canoniques: CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C
• IUPAC Name: 3-(2,2-dimethylchromen-6-yl)-7-hydroxychromen-4-one
• InChIKey: PWAACAMQKVIVPZ-UHFFFAOYSA-N
• INCHI: 1S/C20H16O4/c1-20(2)8-7-13-9-12(3-6-17(13)24-20)16-11-23-18-10-14(21)4-5-15(18)19(16)22/h3-11,21H,1-2H3
• Isomères SMILES: CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C
• Poids moléculaire: 320.34
• Reaxy-Rn: 1395081
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1395081&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Classe Isoflavonoids
      • Subclass Pyranoisoflavonoids

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Classe: Isoflavonoids
• Subclass: Pyranoisoflavonoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyranoisoflavonoids
• Alternative Parents: Isoflavones Hydroxyisoflavonoids 2,2-dimethyl-1-benzopyrans Chromones Pyranones and derivatives Alkyl aryl ethers 1-hydroxy-2-unsubstituted benzenoids Heteroaromatic compounds Oxacyclic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Pyranoisoflavonoid - Isoflavone - Hydroxyisoflavonoid - 2,2-dimethyl-1-benzopyran - Chromone - Benzopyran - 1-benzopyran - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyranone - Alkyl aryl ether - Benzenoid - Pyran - Heteroaromatic compound - Organoheterocyclic compound - Oxacycle - Ether - Organic oxide - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as pyranoisoflavonoids. These are isoflavonoids that contain a pyran ring fused to either of the A, B, or C ring of the isoflavonoid skeleton.
• External Descriptors: Isoflavonoids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Mécanismes d'action

Propriétés chimiques et physiques

• DMSO (mg/mL) Solubilité maximale: 64
• DMSO (mM) Solubilité maximale: 199.788573741838
• Poids moléculaire: 320.300 g/mol
• XLogP3: 3.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 320.105 Da
• Monoisotopic Mass: 320.105 Da
• Topological Polar Surface Area: 55.800 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 576.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1