CX-5011 - Moligand™ , Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase, CAS No.C609626, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase

CAS: C609626 Cat. No.: C609626 PubChem CID: 72200352

GRADE & PURITY Moligand™

Storage

Room temperature

Specifications

Spécifications et pureté

Moligand™

Conditions de stockage de stockage

Room temperature

Grade

Moligand™

Type d'action

INHIBITOR

Mécanisme d'action

Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase

Noms et identifiants

Sourires canoniques

C#Cc1cccc(c1)Nc1nc2cc(ccc2c2c1ncnc2)C(=O)[O-]

IUPAC Name

5-(3-ethynylanilino)pyrimido[4,5-c]quinoline-8-carboxylate

InChIKey

HJGFPNFAFSFDNN-UHFFFAOYSA-M

INCHI

1S/C20H12N4O2/c1-2-12-4-3-5-14(8-12)23-19-18-16(10-21-11-22-18)15-7-6-13(20(25)26)9-17(15)24-19/h1,3-11H,(H,23,24)(H,25,26)/p-1

Isomères SMILES

C#CC1=CC(=CC=C1)NC2=NC3=C(C=CC(=C3)C(=O)[O-])C4=CN=CN=C42

PubChem CID

72200352

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Quinolines and derivatives
      • Subclass Quinoline carboxylic acids

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Quinolines and derivatives
• Subclass: Quinoline carboxylic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinoline carboxylic acids
• Alternative Parents: Aminoquinolines and derivatives Pyrido[3,4-d]pyrimidines Aniline and substituted anilines Aminopyridines and derivatives Pyrimidines and pyrimidine derivatives Imidolactams Heteroaromatic compounds Carboxylic acid salts Acetylides Carboxylic acids Azacyclic compounds Organic oxides Organooxygen compounds Amines Hydrocarbon derivatives Organic anions
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinoline-7-carboxylic acid - Aminoquinoline - Pyrido[3,4-d]pyrimidine - Aniline or substituted anilines - Aminopyridine - Monocyclic benzene moiety - Pyridine - Pyrimidine - Benzenoid - Imidolactam - Heteroaromatic compound - Carboxylic acid salt - Carboxylic acid - Carboxylic acid derivative - Acetylide - Azacycle - Amine - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organic anion - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

PIM1 Tchem Serine/threonine-protein kinase pim-1 (1 Activities)

Discover Target: PIM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)