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Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine selectively inhibits HIV-1 reverse transcriptase (RT) ( IC 50 =0.26 μM) over DNA polymerase α (IC 50 =440 μM) and polymerase δ (IC 50 >550 μM). Delavirdine is an inhibitor of HIV-1 replication and can can be used for the study of AIDs.
| CAS | 136817-59-9 |
|---|---|
| Concentration | 10 mM in DMSO |
| Spécifications et pureté | Moligand™, 10 mM in DMSO |
| Conditions de stockage de stockage | Store at -80°C |
| Expédié en | Dry ice packs + Cold packs |
| Product Description | Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine selectively inhibits HIV-1 reverse transcriptase (RT) ( IC 50 =0.26 μM) over DNA polymerase α (IC 50 =440 μM) and polymerase δ (IC 50 >550 μM). Delavirdine is an inhibitor of HIV-1 replication and can can be used for the study of AIDs. |