Diamide - ≥97%(HPLC) , CAS No.10465-78-8

CAS: 10465-78-8 Cat. No.: D165635 Formule: C₆H₁₂N₄O₂ Poids moléculaire: 172.19 Beilstein Registry Number: 1910410 Numéro CE: 233-951-7

QUALITÉ & PURETÉ ≥97%(HPLC)

Synonyms

TMAD|(+/-)-Secobarbital|Azodicarboxylic acid bis-dimethylamide|1,N-dimethylformamide)|N,N',N'-Tetramethylazobisformamide|N,N,N',N'-Tetramethylazodicarboxamide|N,N,N',N'-Tetramethylazobisformamide|DIAMIDE|Tetramethyldiazenedicarboxamide|A 19315|(E)-1,1'-azobis(N,N-dimethylformamide)|Tetramethylazodicarboxamide|Formamide,1'-azobis[N,N-dimethyl-|Azodicarboxylic acid bis(dimethylamide); diamide|(E)-N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide|Azodicarboxylic acid bis(dimethylamide)|N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide|SDCCGSBI-0050383.P002|N,N,N',N'-Tetramethylazodicarboxamide(TMAD)|(3E)-3-(dimethylcarbamoylimino)-1,1-dimethylurea|(3E)-3-(dimethylcarbamoylimino)-1,1-dimethyl-urea|(E)-1-[(dimethylcarbamoyl)imino]-3,3-dimethylurea|N,N',N'-Tetramethylazoformamide|1,1'-Azobis(N,N-dimethylformamide)|Formamide, 1,1'-azobis(N,N-dimethyl-|N,N',N'-Tetramethylazodicarboxamide|(1E)-1-(dimethyl-carbamoylimino)-3,3-dimethyl-urea|1,1'-Azobis (N,N-dimethyl formamide)|3-(N,N-Dimethylcarbamoylimido)-1,1-dimethylurea|N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide|Diazenedicarboxylic acid bis(N,N-dimethylamide)|N,N,N',N'-Tetramethylazoformamide

Storage

Stocker à -20°C, chargé d'argon

Shipped In

Glacière + blocs de glace

Vue d’ensemble

Utilisé comme agent oxydant des thiols. Le diamide a été utilisé pour titrer la glutathiolation des protéines afin de la distinguer d'autres modifications oxydatives des protéines. Le traitement a augmenté la glutathiolation des protéines en fonction de la concentration et a eu comparativement peu d'effet sur la formation de disulfures entre protéines.

Spécifications

Synonymes

TMAD | (+/-)-Secobarbital | Azodicarboxylic acid bis-dimethylamide | 1,N-dimethylformamide) | N,N',N'-Tetramethylazobisformamide | N,N,N',N'-Tetramethylazodicarboxamide | N,N,N',N'-Tetramethylazobisformamide | DIAMIDE | Tetramethyldiazenedicarboxamide | A 19315 | (E)-1,1'-azobis(N,N-dimethylformamide) | Tetramethylazodicarboxamide | Forma Afficher plus

Spécifications et pureté

≥97%(HPLC)

Conditions de stockage de stockage

Stocker à -20°C, chargé d'argon

Expédié en

Glacière + blocs de glace

Pureté

≥97%(HPLC)

Noms et identifiants

Pubchem Sid

504763663

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504763663

Sourires canoniques

CN(C)C(=O)N=NC(=O)N(C)C

IUPAC Name

(3E)-3-(dimethylcarbamoylimino)-1,1-dimethylurea

InChIKey

VLSDXINSOMDCBK-BQYQJAHWSA-N

INCHI

1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+

Isomères SMILES

CN(C)C(=O)/N=N/C(=O)N(C)C

WGK Allemagne

3

RTECS

LQ1041000

Poids moléculaire

172.19

Beilstein

1910410

Reaxy-Rn

1910409

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1910409&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Organic carbonic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Organic carbonic acids and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic carbonic acids and derivatives
• Alternative Parents: Azo compounds Propargyl-type 1,3-dipolar organic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Carbonic acid derivative - Azo compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as organic carbonic acids and derivatives. These are compounds comprising the organic carbonic acid or a derivative thereof.
• External Descriptors: 1,1'-azobis(N,N-dimethylformamide)

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: water: 19.60-21.00 mg/mL, clear to slightly hazy, orange
• Sensibilité: air sensitive；heat sensitive
• Point de fusion (°C): 113-115 °C
• Poids moléculaire: 172.190 g/mol
• XLogP3: 0.200
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 172.096 Da
• Monoisotopic Mass: 172.096 Da
• Topological Polar Surface Area: 65.300 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 188.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product, and how is it determined?

This product is supplied at ≥97% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 10465-78-8, the molecular formula is C6H12N4O2, and the molecular weight is 172.19 g/mol. InChIKey VLSDXINSOMDCBK-BQYQJAHWSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.