DL-Norvaline - 10mM in Water , CAS No.760-78-1

CAS: 760-78-1 Cat. No.: D425864 Molecular Weight: 117.15 Beilstein Registry Number: 4416 EC Number: 212-082-7

GRADE & PURITY 10mM in Water

Synonyms

DL-2-Aminovaleric Acid | METHYLENEBIS(THIOLACTICACID) | (+/-)-2-Aminopentanoic acid | NORVALINE DL-FORM [MI] | NSC 7904 | Valeric acid, 2-amino- | aminopentanoic acid | .alpha.-Aminovaleric acid | 2-Aminopentanoicacid | D70899 | AKOS000173771 | DL-.alpha.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications

Synonyms

DL-2-Aminovaleric Acid | METHYLENEBIS(THIOLACTICACID) | (+/-)-2-Aminopentanoic acid | NORVALINE DL-FORM [MI] | NSC 7904 | Valeric acid, 2-amino- | aminopentanoic acid | .alpha.-Aminovaleric acid | 2-Aminopentanoicacid | D70899 | AKOS000173771 | DL-.alpha.

Specifications & Purity

10mM in Water

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Names and Identifiers

• Canonical Smiles: CCCC(C(=O)O)N
• IUPAC Name: 2-aminopentanoic acid
• InChIKey: SNDPXSYFESPGGJ-UHFFFAOYSA-N
• INCHI: 1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
• Isomeric SMILES: CCCC(C(=O)O)N
• WGK Germany: 3
• Molecular Weight: 117.15
• Beilstein: 4416
• Reaxy-Rn: 1721160
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721160&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Alpha amino acids
• Alternative Parents: Methyl-branched fatty acids Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-amino acid - Branched fatty acid - Methyl-branched fatty acid - Fatty acid - Fatty acyl - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Primary aliphatic amine - Carbonyl group - Organic oxygen compound - Amine - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
• External Descriptors: a small molecule

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Melt Point(°C): 300°C
• Molecular Weight: 117.150 g/mol
• XLogP3: -2.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 117.079 Da
• Monoisotopic Mass: 117.079 Da
• Topological Polar Surface Area: 63.300 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 82.500
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Qing Xiong, Jing Jin, Liqiong Lv, Zhisi Bu, Shengqiang Tong.  (2018)  Chiral ligand exchange countercurrent chromatography: Enantioseparation of amino acids.  JOURNAL OF SEPARATION SCIENCE,  41  (6): (1479-1488).  [PMID:29323783] [10.1002/jssc.201701117]

2. Xin Li, Bohan Sun, Yanting Qin, Fangfang Yue, Xin Lü.  (2025)  Amelioration of Obesity-Related Disorders in High-Fat Diet-Fed C57BL/6 Mice Following Fecal Microbiota Transplantation From DL-Norvaline-Dosed Mice.  MOLECULAR NUTRITION & FOOD RESEARCH,      [PMID:39791141] [10.1002/mnfr.202400577]

3. Xin Li, Yanting Qin, Fangfang Yue, Xin Lü.  (2025)  Comprehensive Analysis of Fecal Microbiome and Metabolomics Uncovered dl-Norvaline-Ameliorated Obesity-Associated Disorders in High-Fat Diet-Fed Obese Mice by Targeting the Gut Microbiota.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:39808000] [10.1021/acs.jafc.4c06638]

4. Li Xin, Ma Yuntian, Wang Xin, Lü Xin.  (2025)  DL-norvaline inhibited adipogenesis in 3T3-L1 preadipocytes and ameliorated sphingolipid and glycerophospholipid metabolism in obese mice through the PPAR signaling pathway based on lipidomics and transcriptomics.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107215]