DMT-dI Phosphoramidite - ≥98%, total des isomères , CAS No.141684-35-7

CAS: 141684-35-7 Cat. No.: B299891 Formule: C₄₀H₄₇N₆O₇P Poids moléculaire: 754.82 Numéro CE: 853-150-1

GRADE & PURITY ≥98%, total of isomers

Synonyms

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxyinosine | (2R,3S,5R)-2-[[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-5-(6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-Cyanoethyl) Diisopropylphos

Storage

Protégé de la lumière,Stocker à -20°C,Chargé à l'argon

Shipped In

Glacière + blocs de glace

Vue d’ensemble

Phosphoramidite is a modified phosphoramidite monomer used for the oligonucleotide synthesis.

Specifications

Synonymes

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxyinosine | (2R,3S,5R)-2-[[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-5-(6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-Cyanoethyl) Diisopropylphos

Spécifications et pureté

≥98%, total des isomères

Conditions de stockage de stockage

Protégé de la lumière,Stocker à -20°C,Chargé à l'argon

Expédié en

Glacière + blocs de glace

Pureté

≥98%

Noms et identifiants

Sourires canoniques

CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=CNC6=O

IUPAC Name

3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(6-oxo-1H-purin-9-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChIKey

ZKGZROFWRPJVEB-XZYUMQGLSA-N

INCHI

1S/C40H47N6O7P/c1-27(2)46(28(3)4)54(51-22-10-21-41)53-34-23-36(45-26-44-37-38(45)42-25-43-39(37)47)52-35(34)24-50-40(29-11-8-7-9-12-29,30-13-17-32(48-5)18-14-30)31-15-19-33(49-6)20-16-31/h7-9,11-20,25-28,34-36H,10,22-24H2,1-6H3,(H,42,43,47)/t34-,35+,36+,54?/m0/s1

Isomères SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=CNC6=O

Poids moléculaire

754.82

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Classe Nucleoside and nucleotide analogues
      • Subclass Ribonucleoside phosphoramidites

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Classe: Nucleoside and nucleotide analogues
• Subclass: Ribonucleoside phosphoramidites
• Intermediate Tree Nodes: Not available
• Direct Parent: Ribonucleoside phosphoramidites
• Alternative Parents: Alpha amino acid amides Hypoxanthines 6-oxopurines Benzylethers Phenoxy compounds Methoxybenzenes Anisoles Pyrimidones Alkyl aryl ethers N-substituted imidazoles Monosaccharides Hydropyrimidines Vinylogous amides Tetrahydrofurans Heteroaromatic compounds Lactams Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Nitriles Formamidines Dialkyl ethers Carboximidamides Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Ribonucleoside phosphoramidite - Alpha-amino acid amide - Hypoxanthine - Alpha-amino acid or derivatives - 6-oxopurine - Imidazopyrimidine - Benzylether - Phenoxy compound - Methoxybenzene - Phenol ether - Anisole - Pyrimidone - Alkyl aryl ether - Benzenoid - Pyrimidine - N-substituted imidazole - Monosaccharide - 1,6-dihydropyrimidine - Hydropyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Vinylogous amide - Tetrahydrofuran - Azole - Lactam - Formamidine - Oxacycle - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Nitrile - Carbonitrile - Ether - Dialkyl ether - Carboxylic acid derivative - Amidine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as ribonucleoside phosphoramidites. These are ribonucleoside analogues that consist of a nucleobase (usually purine or pyrimidine), linked to a ribose or deoxyribose, which is protected at the 2',3', or 5'-position by a phosphoramidite group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Sensibilité: air sensitive；Moisture sensitive；light sensitive；heat sensitive
• Poids moléculaire: 754.800 g/mol
• XLogP3: 5.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 17
• Exact Mass: 754.324 Da
• Monoisotopic Mass: 754.324 Da
• Topological Polar Surface Area: 142.000 Ų
• Heavy Atom Count: 54
• Formal Charge: 0
• Complexity: 1230.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1