Dyclonine HCl - 10mM in DMSO , Sodium channel alpha subunit blocker, CAS No.536-43-6, Sodium channel alpha subunit blocker

CAS: 536-43-6 Cat. No.: D409239 Formule: C₁₈H₂₇NO₂ · HCl Poids moléculaire: 325.87 Numéro CE: 208-633-6

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

1-​(4-​butoxyphenyl)​-​3-​(1-​piperidinyl)​-1-​propanone,hydrochloride (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Information

Dyclonine HCl Dyclonine HCl is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading t
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonymes

1-​(4-​butoxyphenyl)​-​3-​(1-​piperidinyl)​-1-​propanone,hydrochloride (1:1)

Spécifications et pureté

Moligand™, 10mM in DMSO

Mécanismes biochimiques et physiologiques

Dyclonine HCl is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane\'s permeability to sodium ions, leading to an increased

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

BLOCKER

Mécanisme d'action

Sodium channel alpha subunit blocker

Noms et identifiants

• Isomères SMILES: CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl
• WGK Allemagne: 3
• RTECS: UG8750000
• Poids moléculaire: 325.87
• Reaxy-Rn: 3744808
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3744808&ln=

Propriétés chimiques et physiques

• Point de fusion (°C): 175-176°C

Références

1. Xiaokang Guan, Qiao Lu, Xiangxu Zhao, Xiaowen Yan, Renato Zenobi.  (2023)  Spatio-Temporal Analysis of Anesthetics in Mice by Solid-Phase Microextraction: Dielectric Barrier Discharge Ionization Mass Spectrometry.  ANALYTICAL CHEMISTRY,      [PMID:37560898] [10.1021/acs.analchem.3c02123]

2. Wen-Jing Li, Li-Ying Wen, Yu-Sang Li, He-Bin Tang.  (2026)  Topical Application of Frankincense Oil Extract Potently Ameliorates Psoriasis-like Dermatitis in Mice via Anti-Inflammatory and Skin Barrier-Protective Effects.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  27  (6):   [PMID:41898492] [10.3390/ijms27062629]