Elubrixin - Moligand™, ≥98% , Interleukin-8 receptor B antagonist, CAS No.688763-64-6, Interleukin-8 receptor B antagonist

CAS: 688763-64-6 Cat. No.: E610106 Molecular Weight: 463.31 EC Number: 629-900-7 PubChem CID: 10479502
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
1-(4-chloro-2-hydroxy-3-(piperazin-1-ylsulfonyl)phenyl)-3-(2-chloro-3-fluorophenyl)urea | SB-656933
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
E610106-1mg
3
$79.90
5mg
E610106-5mg
3
$379.90
10mg
E610106-10mg
3
$389.90
25mg
E610106-25mg
2
$926.90
50mg
E610106-50mg
1
$1,249.90
100mg
E610106-100mg
1
$1,999.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM).

Specifications

Synonyms
1-(4-chloro-2-hydroxy-3-(piperazin-1-ylsulfonyl)phenyl)-3-(2-chloro-3-fluorophenyl)urea | SB-656933
Specifications & Purity
Moligand™, ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ANTAGONIST
Mechanism of action
Interleukin-8 receptor B antagonist
Purity
≥98%
Product Properties
ALogP2.5
Names and Identifiers
Pubchem Sid528764392
Canonical SmilesC1CN(CCN1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl
IUPAC Name1-(2-chloro-3-fluorophenyl)-3-(4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)urea
InChIKeyYQYFEGTYCUQBEI-UHFFFAOYSA-N
INCHI1S/C17H17Cl2FN4O4S/c18-10-4-5-13(23-17(26)22-12-3-1-2-11(20)14(12)19)15(25)16(10)29(27,28)24-8-6-21-7-9-24/h1-5,21,25H,6-9H2,(H2,22,23,26)
Isomeric SMILES C1CN(CCN1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl
Alternate CAS 688763-64-6
PubChem CID 10479502
MeSH Entry Terms SB 656933;SB-656933;SB656933
Molecular Weight 463.31

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzenesulfonamides
Intermediate Tree Nodes Not available
Direct ParentBenzenesulfonamides
Alternative Parents N-phenylureas  Benzenesulfonyl compounds  M-chlorophenols  1-hydroxy-4-unsubstituted benzenoids  Fluorobenzenes  Chlorobenzenes  Piperazines  Organosulfonamides  Aryl chlorides  Aryl fluorides  Sulfonyls  Ureas  Azacyclic compounds  Dialkylamines  Carbonyl compounds  Hydrocarbon derivatives  Organic oxides  Organochlorides  Organofluorides  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Benzenesulfonamide - N-phenylurea - Benzenesulfonyl group - 3-halophenol - 3-chlorophenol - 1-hydroxy-4-unsubstituted benzenoid - Chlorobenzene - Fluorobenzene - Halobenzene - Phenol - Aryl chloride - Aryl fluoride - Aryl halide - 1,4-diazinane - Organosulfonic acid amide - Piperazine - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Urea - Azacycle - Secondary aliphatic amine - Organoheterocyclic compound - Secondary amine - Organosulfur compound - Amine - Organic nitrogen compound - Organohalogen compound - Organochloride - Organofluoride - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CXCR2 Tchem C-X-C chemokine receptor type 2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CXCR2 Tchem Interleukin-8 receptor B (3491 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CXCR1 Tchem Interleukin-8 receptor A (2256 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate TypeDateItem
H2429185Certificate of AnalysisMay 22, 2024 E610106
H2429186Certificate of AnalysisMay 22, 2024 E610106
H2429187Certificate of AnalysisMay 22, 2024 E610106
H2429188Certificate of AnalysisMay 22, 2024 E610106
H2429189Certificate of AnalysisMay 22, 2024 E610106
H2429190Certificate of AnalysisMay 22, 2024 E610106
H2429191Certificate of AnalysisMay 22, 2024 E610106
H2429192Certificate of AnalysisMay 22, 2024 E610106
H2429193Certificate of AnalysisMay 22, 2024 E610106
H2429194Certificate of AnalysisMay 22, 2024 E610106
H2429195Certificate of AnalysisMay 22, 2024 E610106
H2429196Certificate of AnalysisMay 22, 2024 E610106

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Chemical and Physical Properties
Molecular Weight463.300 g/mol
XLogP32.500
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass462.033 Da
Monoisotopic Mass462.033 Da
Topological Polar Surface Area119.000 Ų
Heavy Atom Count29
Formal Charge0
Complexity677.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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