Estramustine - Moligand™, 10 mM in DMSO , CAS No.2998-57-4

CAS: 2998-57-4 Cat. No.: E1493726 Molecular Weight: 440.4 EC Number: 221-076-3

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Estramustine is an antineoplastic agent. Estramustine depolymerizes microtnbules by binding to tubulin 1 , exhibits antimitotic activity with an IC 50 value of ~16 μM for mitosis of DU 145 cells. Estramustine blocks cells at mitosis in prostate tumor xenografts.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl
• Alternate CAS: 2998-57-4
• NSC Number: 89201
• MeSH Entry Terms: Emcyt;Estracyt;Estramustin Phosphate;Estramustine;Estramustine Phosphate Sodium;Estramustinphosphate;Leo 275;Leo-275;Leo275;NSC 89199;NSC-89199;NSC89199;Phosphate Sodium, Estramustine;Phosphate, Estramustin
• Molecular Weight: 440.4
• Reaxy-Rn: 1895835
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1895835&ln=

Chemical and Physical Properties

• Refractive Index: 1.58
• Boil Point(°C): 565.8° C at 760 mmHg
• Melt Point(°C): 122-126° C