Etomoxir - Moligand™, 10 mM in DMSO , CAS No.124083-20-1

CAS: 124083-20-1 Cat. No.: E1499129 Formule: C₁₇H₂₃ClO₄ Poids moléculaire: 326.82

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Argon charged,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a ( CPT-1a ), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.

Specifications

Spécifications et pureté

Moligand™, 10 mM in DMSO

Conditions de stockage de stockage

Protected from light,Argon charged,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Noms et identifiants

• Isomères SMILES: CCOC(=O)[C@]1(CO1)CCCCCCOC2=CC=C(C=C2)Cl
• Poids moléculaire: 326.82
• Reaxy-Rn: 8273691
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8273691&ln=

Références

1. Zhonghua Dong, Xiao Li, Xuan Wang, Jingya Xu, Wei Xu.  (2025)  Ergosterol from Edible Fungi: Enhancing Fatty Acid Oxidation via CPT1A to Protect Against Diabetic Kidney Disease.  Food & Function,      [PMID:40704985] [10.1039/D5FO00371G]

2. Cui Tang, Hui Wang, Lina Guo, Chan Zou, Jianming Hu, Hanyong Zhang, Wenhu Zhou, Guoping Yang.  (2023)  CpG-Conjugated Silver Nanoparticles as a Multifunctional Nanomedicine to Promote Macrophage Efferocytosis and Repolarization for Atherosclerosis Therapy.  ACS Applied Materials & Interfaces,      [PMID:37910772] [10.1021/acsami.3c11227]

3. Lingxiang Ran, Qiu Chen, Xingyu Lu, Zhixiang Gao, Fengmei Cui, Xiaolong Liu, Boxin Xue.  (2023)  Novel treatment and insight for irradiation-induced injuries: Dibucaine ameliorates irradiation-induced testicular injury by inhibiting fatty acid oxidation in primary Leydig cells.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:37224756] [10.1016/j.biopha.2023.114903]

4. Jin Nan, Bi Aiwei, Lan Xiaojing, Xu Jun, Wang Xiaomin, Liu Yingluo, Wang Ting, Tang Shuai, Zeng Hanlin, Chen Ziqi, Tan Minjia, Ai Jing, Xie Hua, Zhang Tao, Liu Dandan, Huang Ruimin, Song Yue, Leung Elaine Lai-Han, Yao Xiaojun, Ding Jian, Geng Meiyu, Lin Shu-Hai, Huang Min.  (2019)  Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.  Nature Communications,  10  (1): (1-15).  [PMID:31221965] [10.1038/s41467-019-10427-2]

5. Jiao Shihong, Tang Binghua, Wang Yong, Li Chun, Zeng Zifan, Cui Lixia, Zhang Xuefeng, Shao Mingyan, Guo Dongqing, Wang Qiyan.  (2018)  Pro-angiogenic Role of Danqi Pill Through Activating Fatty Acids Oxidation Pathway Against Coronary Artery Disease.  Frontiers in Pharmacology,      [PMID:30564122] [10.3389/fphar.2018.01414]

6. Jing Wang, Nuli Xie, Shan Lu, Bo Xiao, Yangqin Ou, Qingnian Li, Dexian Liu, Wenhu Zhou.  (2024)  CpG and Rutin Co-Loaded DNA Tetrahedra for Targeted Therapy of Intracerebral Hemorrhage: Synergistic Hematoma Clearance and Neuroinflammation Inhibition.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202403469]

7. Xiangying Zou, Jiayu Jia, Tengfei Zhu, Shouping Cai, Yiman He, Shunde Su, Yu Fang, Jian Li, Guifang Lin, Jun Su.  (2024)  Identification of pine wood nematode (Bursaphelenchus xylophilus) loading response genes in Japanese pine sawyer (Monochamus alternatus) through comparative genomics and transcriptomics.  PEST MANAGEMENT SCIENCE,      [PMID:38511764] [10.1002/ps.8090]

8. Kefan Zheng, Hongdi Cui, Ziheng Tang, Entong Song, Qingran Kong, Jiaming Zhang, Hao Li, Qi Zhao.  (2025)  Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice.  Frontiers in Cell and Developmental Biology,      [PMID:41415208] [10.3389/fcell.2025.1683028]

9. Li Yuan, Han Dongyang, Liu Junjie, Qiao Yuxin, Wei Jiaoxia, Lu Haitao, Yao Li.  (2026)  A novel role for decadienyl-L-carnitine in pulmonary vascular remodeling and the underlying interventional mechanism of osthole.  Chinese Medicine,  21  (1): (87).  [PMID:41840734] [10.1186/s13020-026-01362-8]

Foire aux questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 124083-20-1, the molecular formula is C17H23ClO4, and the molecular weight is 326.82 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.