Exendin-4 - Moligand™, ≥97%, Contains acetic acid:0-15% , Agonist of GLP-1 receptor, CAS No.141758-74-9(free), Agonist of GLP-1 receptor

CAS: 141758-74-9(free) Cat. No.: E107854 Molecular Weight: 4186.57(free) EC Number: 686-356-3
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97% Contains acetic acid:0-15%
Synonyms
HSDB 7789 | LY 2148568 | ITCA 650 | AC2993A | Bydureon Pen | DA 3091 | AC 2993 | UNII-9P1872D4OL | Exenatide [USAN:INN:BAN:JAN] | Exendin-4 | Bydureon | C184H282N50O60S | Exenatide | AC002993 | Exenatide; Exendin-4 | Exendin 4 | SCHEMBL14634818 | PT302
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
E107854-1mg
3
$144.90
5mg
E107854-5mg
3
$219.90
10mg
E107854-10mg
2
$359.90
25mg
E107854-25mg
2
$559.90
50mg
E107854-50mg
1
$759.90
100mg
E107854-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,119.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥97%, Contains acetic acid:0-15% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Exendin-4 is an incretin mimetic peptide, which is composed of 39 amino acids. It is an analog of glukagon-like peptide 1 (GLP-1), and an insulinotropic agent, with a long half-life. It was originally isolated from the venom of Gila monster lizard called Heloderma suspectum.

Specifications

Synonyms
HSDB 7789 | LY 2148568 | ITCA 650 | AC2993A | Bydureon Pen | DA 3091 | AC 2993 | UNII-9P1872D4OL | Exenatide [USAN:INN:BAN:JAN] | Exendin-4 | Bydureon | C184H282N50O60S | Exenatide | AC002993 | Exenatide; Exendin-4 | Exendin 4 | SCHEMBL14634818 | PT302
Specifications & Purity
Moligand™, ≥97%, Contains acetic acid:0-15%
Biochemical and Physiological Mechanisms
Exendin-4, a 39 amino acid peptide, activates GLP-1 (Glukagon-like peptide-1) receptors to increase intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. Exendin-4 stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS ac
Storage
Protected from light, Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of GLP-1 receptor
Note
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Purity
≥97%
Names and Identifiers
Alternate CAS 914454-01-6
Molecular Weight 4186.57(free)

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
A2608017Certificate of AnalysisMay 30, 2024 E107854
E2607117Certificate of AnalysisMay 30, 2024 E107854
F2424206Certificate of AnalysisMay 30, 2024 E107854
F2424207Certificate of AnalysisMay 30, 2024 E107854
F2424208Certificate of AnalysisMay 30, 2024 E107854
F2424209Certificate of AnalysisMay 30, 2024 E107854
F2424210Certificate of AnalysisMay 30, 2024 E107854
F2424211Certificate of AnalysisMay 30, 2024 E107854
F2424212Certificate of AnalysisMay 30, 2024 E107854
F2009059Certificate of AnalysisMar 06, 2024 E107854
Chemical and Physical Properties
Sensitivitylight & Moisture sensitive
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

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