Exendin (5-39) - ≥99% , CAS No.196109-27-0

CAS: 196109-27-0 Cat. No.: E647553 Formule: C₁₆₉H₂₆₂N₄₄O₅₄S Poids moléculaire: 3806.30

QUALITÉ & PURETÉ ≥99%

Storage

Protected from light,Argon charged,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Exendin (5-39) is a potent Glukagon-like peptide 1 ( GLP-1 ) receptor antagonist. Exendin (5-39) improves memory impairment in β-amyloid protein-treated rats

In Vivo

Exendin (5-39) (intracerebroventricular injection; 0.3 μg; once daily; 1-week) increases GLT-1 protein levels in the hippocampus of male Wistar rats. Additionally, hippocampal slices are prepared from Ex-treated or vehicle rats,Exendin (5-39) decreases fEPSP decay time and increases the input-output relation and decreased the paired-pulse ratio in the dentate gyrus (DG). Furthermore, Ex inhibits long-term depression but not long-term potentiation in the DG . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Wistar rats (3 weeks old and 18 days pregnant) Dosage: 0.3 μg Administration: Intracerebroventricular injection; 0.3 μg; once daily; 1-week Result: Inhibited GLT-1 protein levels and inhibited long-term depression in rats.

Form:Solid

IC50& Target:IC50: GLP-1 receptor

Spécifications

Spécifications et pureté

≥99%

Mécanismes biochimiques et physiologiques

Exendin (5-39) is a potent Glukagon-like peptide 1 ( GLP-1 ) receptor antagonist. Exendin (5-39) improves memory impairment in β-amyloid protein-treated rats.

Conditions de stockage de stockage

Protected from light,Argon charged,Desiccated,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

ANTAGONIST

Pureté

≥99%

Noms et identifiants

Poids moléculaire

3806.30