EXP 3174 - Moligand™, ≥98%(HPLC) , Antagonist of AT 1 receptor, CAS No.124750-92-1, Antagonist of AT 1 receptor

CAS: 124750-92-1 Cat. No.: E286809 Formule: C22H21ClN6O2 Poids moléculaire: 436.89 Numéro CE: 112-196-6
DISPONIBLE À COMMANDE
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
Synonyms
2-Butyl-5-chloro-3-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid | GD76OCH73X | ZEUXAIYYDDCIRX-UHFFFAOYSA-N | 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid | E 3174 | L
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Size
USA
Allemagne (EU)*
Price
Qty
10mg
E286809-10mg
3 En stock

9,90$US

14,90$US
Enregistrer 5,00 $US (33.56%)
50mg
E286809-50mg
3 En stock

24,90$US

37,90$US
Enregistrer 13,00 $US (34.30%)
250mg
E286809-250mg
3 En stock

89,90$US

134,90$US
Enregistrer 45,00 $US (33.36%)
1g
E286809-1g
3 En stock

277,90$US

416,90$US
Enregistrer 139,00 $US (33.34%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonymes
2-Butyl-5-chloro-3-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid | GD76OCH73X | ZEUXAIYYDDCIRX-UHFFFAOYSA-N | 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid | E 3174 | L
Spécifications et pureté
Moligand™, ≥98%(HPLC)
Mécanismes biochimiques et physiologiques
Potent and selective noncompetitive AT1receptor antagonist (IC50= 37 nM). Reduces blood pressure in a rat model. Active metabolite oflosartan potassium.
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Grade
Moligand™
Type d'action
ANTAGONIST
Mécanisme d'action
Antagonist of AT 1 receptor
Pureté
≥98%(HPLC)
Noms et identifiants
Pubchem Sid504756653
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504756653
Sourires canoniquesCCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)Cl
IUPAC Name2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
InChIKeyZEUXAIYYDDCIRX-UHFFFAOYSA-N
INCHI1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28)
Isomères SMILES CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)Cl
Poids moléculaire 436.89
Reaxy-Rn 4830084
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4830084&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClasseBenzene and substituted derivatives
SubclassBiphenyls and derivatives
Intermediate Tree Nodes Not available
Direct ParentBiphenyls and derivatives
Alternative Parents Phenyltetrazoles and derivatives  1,2,4,5-tetrasubstituted imidazoles  Carbonylimidazoles  Aryl chlorides  N-substituted imidazoles  Vinylogous halides  Heteroaromatic compounds  Azacyclic compounds  Carboxylic acids  Monocarboxylic acids and derivatives  Organochlorides  Organooxygen compounds  Organonitrogen compounds  Hydrocarbon derivatives  Organopnictogen compounds  Organic oxides  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Biphenyl - Phenyltetrazole - 1,2,4,5-tetrasubstituted imidazole - Imidazole-4-carbonyl group - Aryl chloride - Aryl halide - N-substituted imidazole - Azole - Heteroaromatic compound - Imidazole - Vinylogous halide - Tetrazole - Azacycle - Carboxylic acid derivative - Carboxylic acid - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organohalogen compound - Organochloride - Organonitrogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
External Descriptors imidazoles - organochlorine compound - biphenylyltetrazole
Structure 3D
Modèle de structure chimique interactif





Cibles associées (humaines)
AGTR1 Tclin Type-1 angiotensin II receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cibles associées (non humaines)
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr1b Type-1B angiotensin II receptor (525 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Angiotensin II type 1a (AT-1a) receptor (440 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryctolagus cuniculus (11301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr1b Angiotensin II receptor (1735 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr1b Angiotensin II receptor (AT-1) type-1 (1480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mécanismes d'action
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateArticle
H2206701Certificate of AnalysisMay 12, 2025 E286809
H2206702Certificate of AnalysisMay 12, 2025 E286809
H2206703Certificate of AnalysisMay 12, 2025 E286809
H2206832Certificate of AnalysisMay 12, 2025 E286809
Propriétés chimiques et physiques
SolubilitéSolvent:DMSO, Max Conc. mg/mL: 43.69, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 43.69, Max Conc. mM: 100
Poids moléculaire436.900 g/mol
XLogP35.000
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Exact Mass436.141 Da
Monoisotopic Mass436.141 Da
Topological Polar Surface Area110.000 Ų
Heavy Atom Count31
Formal Charge0
Complexity590.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculateurs de solution
Avis

Avis des clients

Foire aux questions

What are the CAS number, molecular formula and molecular weight?
The CAS Number is 124750-92-1, the molecular formula is C22H21ClN6O2, and the molecular weight is 436.89 g/mol. InChIKey ZEUXAIYYDDCIRX-UHFFFAOYSA-N.
What is the purity of this product, and how is it determined?
This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

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