Factor IXa Beta, CAS No.9001-28-9

CAS: 9001-28-9 Cat. No.: np330899

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; Pre-lyophilization Protein Concentration: See COA

Accession #

P00740

Bioactivity

See COA

Overview

Prepared from Human Factor IX by activation with Human Factor XIa. The XIa is removed after activation. Complete activation is observed by SDS-PAGE. The Factor XIa activates Factor IX in a two-step reaction. In the first step, an internal Arg-Ala bond is cleaved, and in the second step, an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce Factor IXaβ.

Buffer composition = 50mM MES/0.6M NaCl/pH 6.0-NaOH

Extinction Coefficient (1%) = 14.3

Molecular Weight = 45,000 daltons

The above protein was purified from Human plasma that was tested and found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA.Donors are screened for CJD (Creutzfeldt-Jakob Disease).

Specifications

Product Name

Factor IXa Beta, CAS No.9001-28-9

Synonyms

Human Factor IXa β | Human Factor IXa Beta | Human Factor IXa Beta Native Protein | Native Human Factor IXa Beta protein | Coagulation Factor IXa Beta Human | Factor IXab | Factor IXaβ | F9 | FIX | P19 | PTC | HEMB | THPH8 | F9 p22

Grade

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Specifications & Purity

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; Pre-lyophilization Protein Concentration: See COA

Biochemical and Physiological Mechanisms

Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa. Post-translational: Activated by fac

Bioactivity

See COA

Accession #

P00740

Predicted molecular weight

45 kDa

CAS

9001-28-9

Enzyme Commission Number

EC 3.4.21.22

Molecule Type

Enzyme

Storage and Shipping

Concentration

from Human plasma; Pre-lyophilization Protein Concentration: See COA

Reconstitution

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

Storage

Store at 2-8°C

Shipped In

Wet ice

Stability And Storage

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.