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Is Friedel-Crafts alkylation reversible?

· Published 9 oct. 2023 · Updated 9 juin 2025

Is Friedel-Crafts alkylation reversible?

Friedel-Crafts alkylation of benzene is a reversible reaction that can occur. The Friedel-Crafts alkylation of benzene connects the alkyl group to the benzene molecule through electrophilic aromatic substitution. If excessive halogenated acids are produced, the reaction may reverse.

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Da — when not otherwise indicated, molecular weight units are daltons. Mw — weight-average molecular weight. Mn — number-average molecular weight.

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Aladdin Scientific. "Is Friedel-Crafts alkylation reversible?" Aladdin Knowledge Base, updated 9 juin 2025. https://www.aladdinsci.com/us_fr/faqs/is-friedel-crafts-alkylation-reversible-en.html

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