Fenthion solution - analytical standard, 1.00mg/ml in methanol , CAS No.55-38-9

CAS: 55-38-9 Cat. No.: F114191 Molecular Weight: 278.33 Beilstein Registry Number: 1974129 EC Number: 200-231-9
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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. 1.00mg/ml in methanol
Synonyms
SCHEMBL26907 | Tiguvon | BAY 29493 | Dimethyl methylthiotolyl phosphorothioate | O,O-Dimethyl O-(4-methylthio-3-methylphenyl) phosphorothioate | O,O-Dimethyl O-4-methylthio-m-tolyl phosphorothioate | Spectrum4_000695 | Fenthion [BSI:ISO] | CCRIS 310 | Fen
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2ml
F114191-2ml
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Why this grade

analytical standard, 1.00mg/ml in methanol Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Room temperature Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 34 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
SCHEMBL26907 | Tiguvon | BAY 29493 | Dimethyl methylthiotolyl phosphorothioate | O, O-Dimethyl O-(4-methylthio-3-methylphenyl) phosphorothioate | O, O-Dimethyl O-4-methylthio-m-tolyl phosphorothioate | Spectrum4_000695 | Fenthion [BSI:ISO] | CCRIS 310 | Fen
Specifications & Purity
analytical standard, 1.00mg/ml in methanol
Storage
Protected from light, Room temperature
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Analytical standard
Names and Identifiers
Canonical SmilesCC1=C(C=CC(=C1)OP(=S)(OC)OC)SC
IUPAC Namedimethoxy-(3-methyl-4-methylsulfanylphenoxy)-sulfanylidene-λ5-phosphane
InChIKeyPNVJTZOFSHSLTO-UHFFFAOYSA-N
INCHI1S/C10H15O3PS2/c1-8-7-9(5-6-10(8)16-4)13-14(15,11-2)12-3/h5-7H,1-4H3
Isomeric SMILES CC1=C(C=CC(=C1)OP(=S)(OC)OC)SC
UN Number 3018
Packing Group I
Molecular Weight 278.33
Beilstein 1974129
Reaxy-Rn 1974129
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1974129&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassOrganic thiophosphoric acids and derivatives
SubclassThiophosphoric acid esters
Intermediate Tree Nodes Aryl thiophosphates
Direct ParentPhenyl thiophosphates
Alternative Parents Thiophosphate triesters  Thiophenol ethers  Phenoxy compounds  Toluenes  Alkylarylthioethers  Sulfenyl compounds  Organooxygen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Phenyl thiophosphate - Phenoxy compound - Aryl thioether - Thiophosphate triester - Thiophenol ether - Toluene - Alkylarylthioether - Monocyclic benzene moiety - Benzenoid - Thioether - Sulfenyl compound - Organosulfur compound - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenyl thiophosphates. These are organothiophosphorus compounds that contain a thiophosphoric acid O-esterified with a phenyl group.
External Descriptors Organophosphorus insecticides
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AHR Tclin Aryl hydrocarbon receptor (1071 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cheumatopsyche (45 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Daphnia magna (43 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
F2222327Certificate of AnalysisJan 20, 2026 F114191
E2308573Certificate of AnalysisFeb 07, 2025 F114191
A2211886Certificate of AnalysisDec 21, 2021 F114191
Chemical and Physical Properties
SensitivityLight sensitive.
Flash Point(°C)>100°C
Molecular Weight278.300 g/mol
XLogP34.100
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass278.02 Da
Monoisotopic Mass278.02 Da
Topological Polar Surface Area85.100 Ų
Heavy Atom Count16
Formal Charge0
Complexity254.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Cong Jiang, Huimin Zhong, Jiahui Zou, Guancheng Zhu, Yanyan Huang.  (2023)  CuCeTA nanoflowers as an efficient peroxidase candidate for direct colorimetric detection of glyphosate.  Journal of Materials Chemistry B,  11  (40): (9630-9638).  [PMID:37750214] [10.1039/D3TB01455J]
2. Xiaomei Chen, Liulin Wei, Qian Liu, Xueyun Gao, Jingchan Zhao.  (2023)  Application of temperature-sensitive hyperbranched polysiloxanes for the determination of polycyclic aromatic hydrocarbons in foodstuffs.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2023.109364]
3. Wenhui Hao, Gengli Huang, Guoyong Jiang, Sa-adu Abiola Dauda, Fuwei Pi.  (2023)  Direct phoxim sensing based on fluorescent metal-organic framework of Nu-1000 induced FRET.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2023.102967]
4. Kai Zhang, Liangzi Wang, Jingitao liu, Shiyu Zhao, Longfei Ding, Binhua Zhou, Bo Zhao.  (2023)  A Highly Sensitive Electrochemical Methamidophos Immobilized AChE Biosensor for Organophosphorus Pesticides Detection.  International Journal of Electrochemical Science,      [PMID:] [10.20964/2022.04.44]
5. Haoyue Han, Shangzhi Ding, Yanling Geng, Zhaoyu Qiao, Xuemei Li, Rongyu Wang, Xiqing Zhang, Wenhua Ji.  (2022)  Preparation of a pyridyl covalent organic framework via Heck cross-coupling for solid-phase microextraction of perfluoropolyether carboxylic acids in food.  FOOD CHEMISTRY,      [PMID:36156398] [10.1016/j.foodchem.2022.134310]
6. Yufeng Zhang, Lixia Yang, Chang Sun, Chao Huang, Bixue Zhu, Qianjun Zhang, Dongmei Chen.  (2022)  Aptamer-based sensor for specific recognition of malathion in fruits and vegetables by surface-enhanced Raman spectroscopy and electrochemistry combination.  ANALYTICA CHIMICA ACTA,      [PMID:35934378] [10.1016/j.aca.2022.340148]
7. Hengjia Zhu, Peng Liu, Lizhang Xu, Mengzhu Wang, Jianming Pan, Xiangheng Niu.  (2021)  Emulsion-templated construction of enzyme-nanozyme integrated hierarchically porous hydrogels for smartphone-assisted pesticide biosensing.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2021.133669]
8. Xiaojie Shi, Huimin Liu, Mei Zhang, Fengzhen Yang, Jiansen Li, Yemin Guo, Xia Sun.  (2021)  Ultrasensitive electrochemiluminescence aptasensor based on AuNPs@MWCNTs and Au@AgNPs for detection of profenofos residues.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2021.130663]
9. Guozheng Zhao, Binhua Zhou, Xiuwen Wang, Jian Shen, Bo Zhao.  (2021)  Detection of organophosphorus pesticides by nanogold/mercaptomethamidophos multi-residue electrochemical biosensor.  FOOD CHEMISTRY,      [PMID:33735695] [10.1016/j.foodchem.2021.129511]
10. Xiaomin Xie, Binhua Zhou, Yonglei Zhang, Guozheng Zhao, Bo Zhao.  (2021)  A multi-residue electrochemical biosensor based on graphene/chitosan/parathion for sensitive organophosphorus pesticides detection.  CHEMICAL PHYSICS LETTERS,      [PMID:] [10.1016/j.cplett.2021.138355]
11. Linfeng Chen, Xike Tian, Yong Li, Liqiang Lu, Yulun Nie, Yanxin Wang.  (2020)  Broad-spectrum pesticide screening by multiple cholinesterases and thiocholine sensors assembled high-throughput optical array system.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:33254811] [10.1016/j.jhazmat.2020.123830]
12. Hui-Fang Cui, Ting-Ting Zhang, Qi-Yan Lv, Xiaojie Song, Xiao-Jing Zhai, Gai-Gai Wang.  (2019)  An acetylcholinesterase biosensor based on doping Au nanorod@SiO2 nanoparticles into TiO2-chitosan hydrogel for detection of organophosphate pesticides.  BIOSENSORS & BIOELECTRONICS,      [PMID:31252259] [10.1016/j.bios.2019.111452]
13. Kang Yan, Li Long, Chen Wanchao, Zhang Feiyu, Du Yiping, Wu Ting.  (2018)  Rapid In Situ SERS Analysis of Pesticide Residues on Plant Surfaces Based on Micelle Extraction of Targets and Stabilization of Ag Nanoparticle Aggregates.  Food Analytical Methods,  11  (11): (3161-3169).  [PMID:] [10.1007/s12161-018-1290-2]
14. Hui Ouyang, Wenwen Wang, Qi Shu, Zhifeng Fu.  (2018)  Novel chemiluminescent immunochromatographic assay using a dual-readout signal probe for multiplexed detection of pesticide residues.  ANALYST,  143  (12): (2883-2888).  [PMID:29790876] [10.1039/C8AN00661J]
15. Yonghui Nie, Yuanjie Teng, Pan Li, Wenhan Liu, Qianwei Shi, Yuchao Zhang.  (2017)  Label-free aptamer-based sensor for specific detection of malathion residues by surface-enhanced Raman scattering.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:29045930] [10.1016/j.saa.2017.10.030]
16. Qi Shu, Limin Wang, Hui Ouyang, Wenwen Wang, Fengquan Liu, Zhifeng Fu.  (2016)  Multiplexed immunochromatographic test strip for time-resolved chemiluminescent detection of pesticide residues using a bifunctional antibody.  BIOSENSORS & BIOELECTRONICS,      [PMID:27664410] [10.1016/j.bios.2016.09.057]
17. Qiong Jiang, Qin Liu, Qiliang Chen, Wenjie Zhao, Guoqiang Xiang, Lijun He, Xiuming Jiang, Shusheng Zhang.  (2016)  Dicationic polymeric ionic-liquid-based magnetic material as an adsorbent for the magnetic solid-phase extraction of organophosphate pesticides and polycyclic aromatic hydrocarbons.  JOURNAL OF SEPARATION SCIENCE,  39  (16): (3221-3229).  [PMID:27357486] [10.1002/jssc.201600267]
18. Hui Ouyang, Limin Wang, Shijia Yang, Wenwen Wang, Lin Wang, Fengquan Liu, Zhifeng Fu.  (2015)  Chemiluminescence Reaction Kinetics-Resolved Multianalyte Immunoassay Strategy Using a Bispecific Monoclonal Antibody as the Unique Recognition Reagent.  ANALYTICAL CHEMISTRY,      [PMID:25622025] [10.1021/ac5045093]
19. Xiaojuan Liu, Chenghua Zong, Kelong Ai, Wenhui He, Lehui Lu.  (2012)  Engineering Natural Materials as Surface-Enhanced Raman Spectroscopy Substrates for In situ Molecular Sensing.  ACS Applied Materials & Interfaces,      [PMID:23170894] [10.1021/am302376q]
20. Zirou Wang, Sitian Gu, Yu Ma, Huixiao Duo, Wei Wu, Qingli Yang, Xiudan Hou.  (2024)  An efficient PCN-224/graphene aerogel-based extraction method for monitoring the degradation of organophosphorus pesticides in juice.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:39509855] [10.1016/j.chroma.2024.465500]
21. Kangmiao Guo, Xiaokun Wu, Fan Zhang, Ying Cao, Zenglei Tan, Shuwen Xiao, Lijie Wu.  (2024)  Deep Eutectic Solvents-Based Ultrasonic-Assisted Dispersive Liquid–Liquid Microextraction for the Determination of Organophosphorus Pesticides in Honeysuckle Dew Samples.  MOLECULES,  29  (14): (3423).  [PMID:39065001] [10.3390/molecules29143423]
22. Yaqing Zhao, Yaming Sun, Chenchen Song, Hailiang Zhao, Shiqi Chai, Xuemeng Xu, Lijun He.  (2025)  Defect-rich Co/N-doped hierarchically porous carbons for rapid and highly efficient adsorption of organophosphorus pesticides from environmental water.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:39855024] [10.1016/j.chroma.2025.465700]
23. Luqi He, Peihuan He, Jiacong Li, Meng Xiong, Yeshun Zhang, Hui Yan.  (2024)  Fast and on-site detection of fenthion in rice using core-shell Au@Ag nanoparticles and a portable Raman spectrometer.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2024.106856]
24. Dan Zhao, Gang Yu, Miaoxiu Ge, Mingdai Han, Haibing Meng, Wei Xiong, Luhong Wen.  (2024)  Post-modified linker functionalization of metal organic frameworks for high-efficiency adsorption and quantification of trace organophosphorus pesticides in environmental water.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.127470]
25. Xiaoning Wang, Xin Sui, Yangyang Sun, Ziqi Cui, Ning Ma, Shuai Wang, Jun Yang, Fengying Liu, Weijie Yang, Zhenyu Xiao, Tong Zhu, Yuan Luo, Yongan Wang.  (2024)  Potential Common Mechanisms of Cytotoxicity Induced by Organophosphorus Pesticides via NLRP3 Inflammasome Activation.  GeoHealth,  (4): (e2023GH000888).  [PMID:38638206] [10.1029/2023GH000888]
26. Lingjun Geng, Jingjing Liu, Jingcheng Huang, Haifang Wang, Peisen Li, Rui Xu, Chengqiang Li, Haowei Dong, Ibrahim A. Darwish, Yemin Guo, Xia Sun.  (2024)  Preparation strategy of molecularly imprinted polymers adsorbent based on multifunctional carrier for precise identification and enrichment of fenthion.  FOOD CHEMISTRY,      [PMID:39612837] [10.1016/j.foodchem.2024.142190]
27. Xueer Lin, Jiahui Zou, Guancheng Zhu, Linfeng Pang, Yuqi Chen, Yanyan Huang.  (2025)  Cu-MOFs nanozyme with POD-like activity for the enrichment, identification, and intelligent colorimetric detection of omethoate.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107533]
28. Junjie Qi, Wenhui Hao, Jingkun Li, Yuqi Wan, Guoyong Jiang, Yukihiro Ozaki, Fuwei Pi.  (2025)  PCN222(Fe)@NU-1000 based MOF-on-MOF dual-signal sensing strategy for sensitive detection of phoxim.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.115260]
29. Lingjun Geng, Jingcheng Huang, Haowei Dong, Haifang Wang, Rui Xu, Zhiping Yu, Ibrahim A. Darwish, Yemin Guo, Xia Sun.  (2025)  GO-SELEX-enhanced dual-recognition sensor for highly specific detection of azamethiphos.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40222065] [10.1016/j.jhazmat.2025.138252]
30. Yang Xiaoying, Liu Qian, Luo Longhui, Tian Wei, Kang Chao, Yang Wanliang, Li Tianxiang, Chen Dongmei, Yan Xiufang.  (2025)  Construction of a silver nanoparticle SERS aptamer-based sensor and its specific recognition of diazinon.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:40536668] [10.1007/s00216-025-05956-3]
31. Donglin Xiang, Xiao Wang, Chun Ji, Laping He, Yuangen Wu, Han Tao.  (2026)  An electrochemical sensing strategy for organophosphorus pesticides based on dual-enzyme synergistic catalysis of plant esterase and diatomic FeCo–NC nanozyme.  FOOD CHEMISTRY,      [PMID:41548273] [10.1016/j.foodchem.2026.147963]
32. Yeru Liu, Mengxue Zhang, Xiaolei Zhao, Yifan Zhou, Hongna Yin, Li Zhou, Zhicheng Liu, Qiyong Cai.  (2026)  In situ biosynthetic-driven fluorescence sensor combined with a smartphone platform for portable detection of glyphosate.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2026.117118]
33. Longying Zhao, Jiayu Chen, Donglin Xiang, Mierban Dawuti, Laping He, Yuangen Wu, Han Tao.  (2026)  Electrochemical Sensing of Organophosphorus Pesticides Based on Plant Esterase-Triggered Silver Deposition with CuNi-DAC Signal Amplification.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2026.148562]
34. Li Guangyan, Cheng Xiu, Zhu Minnan, Tian Yayang, Chen Linfeng.  (2026)  Self-cascade colorimetric sensing of profenofos synergistically driven by phosphatase- and laccase-like activities of Ce-MOF nanozymes.  MICROCHIMICA ACTA,  193  (4): (239).  [PMID:] [10.1007/s00604-026-07979-8]
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