Glycodeoxycholic acid monohydrate - Moligand™, ≥97% , CAS No.360-65-6

CAS: 360-65-6 Cat. No.: G113438 Molecular Weight: 449.62(anhy) Beilstein Registry Number: 2954947 EC Number: 623-793-0
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
Synonyms
GLYCODEOXYCHOLIC_ACID | F20550 | N-((3-alpha,5-beta,12-alpha)-3,12-Dihydroxy-24-oxocholan-24-yl)-glycine | Spectrum5_002013 | 3alpha,12alpha-Dihydroxy-5beta-cholan-24-oylglycine | CHEBI:27471 | 5-beta-Cholan-24-oic acid, glycodeoxy- | Glycyldeoxycholic ac
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100mg
G113438-100mg
1
$14.90
500mg
G113438-500mg
3
$42.90
1g
G113438-1g
1
$59.90
5g
G113438-5g
1
$166.90
25g
G113438-25g
1
$429.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
GLYCODEOXYCHOLIC_ACID | F20550 | N-((3-alpha, 5-beta, 12-alpha)-3, 12-Dihydroxy-24-oxocholan-24-yl)-glycine | Spectrum5_002013 | 3alpha, 12alpha-Dihydroxy-5beta-cholan-24-oylglycine | CHEBI:27471 | 5-beta-Cholan-24-oic acid, glycodeoxy- | Glycyldeoxycholic ac
Specifications & Purity
Moligand™, ≥97%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Purity
≥97%
Names and Identifiers
Pubchem Sid504762362
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504762362
Canonical SmilesCC(CCC(=O)NCC(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C
IUPAC Name2-[[(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
InChIKeyWVULKSPCQVQLCU-BUXLTGKBSA-N
INCHI1S/C26H43NO5/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-/m1/s1
Isomeric SMILES C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
WGK Germany 3
RTECS MB9670000
Molecular Weight 449.62(anhy)
Beilstein 2954947
Reaxy-Rn 24879002
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24879002&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassSteroids and steroid derivatives
SubclassBile acids, alcohols and derivatives
Intermediate Tree Nodes Not available
Direct ParentGlycinated bile acids and derivatives
Alternative Parents Dihydroxy bile acids, alcohols and derivatives  3-alpha-hydroxysteroids  12-hydroxysteroids  N-acyl-alpha amino acids  N-acyl amines  Secondary carboxylic acid amides  Secondary alcohols  Cyclic alcohols and derivatives  Monocarboxylic acids and derivatives  Carboxylic acids  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic homopolycyclic compounds
Substituents Glycinated bile acid - Dihydroxy bile acid, alcohol, or derivatives - Hydroxy bile acid, alcohol, or derivatives - 3-hydroxysteroid - 12-hydroxysteroid - Hydroxysteroid - 3-alpha-hydroxysteroid - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - Fatty amide - Fatty acyl - N-acyl-amine - Cyclic alcohol - Carboxamide group - Secondary alcohol - Secondary carboxylic acid amide - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Hydrocarbon derivative - Organic oxide - Alcohol - Organic nitrogen compound - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Aliphatic homopolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as glycinated bile acids and derivatives. These are compounds with a structure characterized by the presence of a glycine linked to a bile acid skeleton.
External Descriptors Glycine conjugates
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
SLC10A2 Tclin Ileal bile acid transporter (415 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GPBAR1 Tchem G-protein coupled bile acid receptor 1 (1723 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Slco1a1 Solute carrier organic anion transporter family member 1A1 (265 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc10a2 Ileal sodium/bile acid cotransporter (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot NumberCertificate TypeDateItem
L1803135Certificate of AnalysisJun 15, 2026 G113438
G1804163Certificate of AnalysisFeb 05, 2026 G113438
A2620472Certificate of AnalysisDec 31, 2025 G113438
A2620473Certificate of AnalysisDec 31, 2025 G113438
A2620474Certificate of AnalysisDec 31, 2025 G113438
A2605076Certificate of AnalysisNov 20, 2024 G113438
A2605139Certificate of AnalysisNov 20, 2024 G113438
L2402314Certificate of AnalysisNov 20, 2024 G113438
L2410018Certificate of AnalysisNov 20, 2024 G113438
D2415402Certificate of AnalysisApr 23, 2024 G113438
J2515040Certificate of AnalysisApr 23, 2024 G113438
J2424766Certificate of AnalysisApr 02, 2024 G113438
J2424770Certificate of AnalysisApr 02, 2024 G113438
A2426068Certificate of AnalysisFeb 05, 2024 G113438
J2213161Certificate of AnalysisOct 14, 2022 G113438

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Chemical and Physical Properties
Molecular Weight449.600 g/mol
XLogP34.300
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass449.314 Da
Monoisotopic Mass449.314 Da
Topological Polar Surface Area107.000 Ų
Heavy Atom Count32
Formal Charge0
Complexity727.000
Isotope Atom Count0
Defined Atom Stereocenter Count10
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Tingting Yang, Lin Li, Jiale Pang, Cai Heng, Chujing Wei, Xue Wang, Ziyin Xia, Xin Huang, Luyong Zhang, Zhenzhou Jiang.  (2023)  Modulating intestinal barrier function by sphingosine-1-phosphate receptor 1 specific agonist SEW2871 attenuated ANIT-induced cholestatic hepatitis via the gut-liver axis.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:37924700] [10.1016/j.intimp.2023.111150]
2. Xiaoxu Cheng, Zifeng Pi, Zhong Zheng, Shu Liu, Fengrui Song, Zhiqiang Liu.  (2022)  Combined 16S rRNA gene sequencing and metabolomics to investigate the protective effects of Wu-tou decoction on rheumatoid arthritis in rats.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:35447521] [10.1016/j.jchromb.2022.123249]
3. Zhicheng Duan, Tingting Yang, Lin Li, Xue Wang, Chujing Wei, Ziyin Xia, Yuanyuan Chai, Xin Huang, Luyong Zhang, Zhenzhou Jiang.  (2022)  Comparison of bile acids profiles in the enterohepatic circulation system of mice and rats.  JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY,      [PMID:35341917] [10.1016/j.jsbmb.2022.106100]
4. Chen Lirong, Guo Yuqiu, Li Xiaoyue, Gong Kuijie, Liu Kaichang.  (2021)  Phenolics and related in vitro functional activities of different varieties of fresh waxy corn: a whole grain.  BMC Chemistry,  15  (1): (1-9).  [PMID:33648574] [10.1186/s13065-021-00740-7]
5. Yufei Sun, Zhiqiang Liu, Zifeng Pi, Fengrui Song, Jianlin Wu, Shu Liu.  (2021)  Poria cocos could ameliorate cognitive dysfunction in APP/PS1 mice by restoring imbalance of Aβ production and clearance and gut microbiota dysbiosis.  PHYTOTHERAPY RESEARCH,  35  (5): (2678-2690).  [PMID:33432644] [10.1002/ptr.7014]
6. Xiaofen Zhang, Ziyao Yang, Ziyu Shi, Zijia Zhu, Cai Li, Zhicheng Du, Yiding Zhang, Zipeng Wang, Zhenrui Jiao, Xin Tian, Ji Zhang, Wenlong Zhai, Quancheng Kan.  (2020)  Analysis of bile acid profile in plasma to differentiate cholangiocarcinoma from benign biliary diseases and healthy controls.  JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY,      [PMID:33130021] [10.1016/j.jsbmb.2020.105775]
7. Yuan Gao, Yujun Liu, Mengying Sun, Heping Zhang, Guangqing Mu, Yanfeng Tuo.  (2020)  Physiological function analysis of Lactobacillus plantarum Y44 based on genotypic and phenotypic characteristics.  JOURNAL OF DAIRY SCIENCE,      [PMID:32418691] [10.3168/jds.2019-18047]
8. Guan-Lin Chen, Song-Gen Chen, Ying-Qing Xie, Fu Chen, Ying-Ying Zhao, Chun-Xia Luo, Yong-Qing Gao.  (2015)  Total phenolic, flavonoid and antioxidant activity of 23 edible flowers subjected to in vitro digestion.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2015.05.028]
9. Zhang Pingping, Wang Huimin, Liang Man, Wang Zhifang, Liu Chunlong, Han Yanlin.  (2024)  A candidate reference measurement procedure for quantification of glycocholic acid in human serum based on isotope dilution liquid chromatography-tandem mass spectrometry.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:39046504] [10.1007/s00216-024-05449-9]
10. Shun Zhang, Ting Cai, Jing Lin, Jia-Juan Liu, Yong-Gang Zhao, Min-Yi Cao.  (2024)  Analysis of 15 bile acids in human plasma based on C18 functionalized magnetic organic polymer nanocomposite coupled with liquid chromatography-tandem mass spectrometry.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:38704923] [10.1016/j.chroma.2024.464962]
11. Xinye Shi, Yuandi Xue, Yuxin Tu, Canrong Chen, Yajing Zhang, Zian Lin, Zongwei Cai.  (2024)  Covalent organic framework-based solid phase microextraction coupled with electrospray ionization mass spectrometry for the quantitative assessment of abnormal bile acids by triclosan exposure in mice.  TALANTA,      [PMID:39700720] [10.1016/j.talanta.2024.127398]
12. Qian Fang, Xiaoying Hou, Limei Fan, Yufei Deng, Xiaoxuan Li, Hongyun Zhang, Haiping Wang, Zhengqi Fu, Binlian Sun, Xiji Shu, Hongzhi Du, Yuchen Liu.  (2025)  Gut microbiota derived DCA enhances FOLFOX efficacy via Ugt1a6b mediated enterohepatic circulation in colon cancer.  PHARMACOLOGICAL RESEARCH,      [PMID:39894186] [10.1016/j.phrs.2025.107636]
13. Zeyun Li, Xueya Zhu, Chenhao Li, Ruiting Tang, Yuanyuan Zou, Shuaibing Liu.  (2024)  Integrated serum metabolomics, 16S rRNA sequencing and bile acid profiling to reveal the potential mechanism of gentiopicroside against nonalcoholic steatohepatitis in lean mice.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:38972531] [10.1016/j.jep.2024.118526]
14. Lei Zhang, Xu Liu, Tenghui Jin, Jing Dong, Xiaodong Li, Youyi Zhang, Dongyang Liu.  (2024)  Isomers-oriented separation of forty-five plasma bile acids with liquid chromatography-tandem mass spectrometry.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:38520985] [10.1016/j.chroma.2024.464827]
15. Xianjiang Ye, Ran Yang, Zhizhi Yang, Baote Huang, Talha Riaz, Chao Zhao, Jicheng Chen.  (2025)  Novel angiotensin-I-converting enzyme (ACE) inhibitory peptides from Porphyra haitanensis: Screening, digestion stability, and mechanistic insights.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.106460]
16. Hang Yang, Tingting Yang, Jiaxin Ding, Xue Wang, Xi Chen, Jia Liu, Ting Shu, Ziteng Wu, Lixin Sun, Xin Huang, Zhenzhou Jiang, Luyong Zhang.  (2024)  Taurocholic acid represents an earlier and more sensitive biomarker and promotes cholestatic hepatotoxicity in ANIT-treated rats.  JOURNAL OF APPLIED TOXICOLOGY,      [PMID:39030796] [10.1002/jat.4669]
17. Guan-Lin Chen, Song-Gen Chen, Fu Chen, Ying-Qing Xie, Men-Di Han, Chun-Xia Luo, Ying-Ying Zhao, Yong-Qing Gao.  (2015)  Nutraceutical potential and antioxidant benefits of selected fruit seeds subjected to an in vitro digestion.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2015.11.003]
18. Juntao Yu, Tonghao Du, Xingyu Zhu, Jiajia Zhang, Chengzhe Liu, Xiaobin Ruan, Xiaoxia Sun, Li Yang, Tao Xiong, Mingyong Xie, Tao Huang.  (2026)  From genes to functions: Multifunctional probiotic properties of Lacticaseibacillus paracasei NCU215 unveiled by genomic analysis and experimental evidence.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2026.108525]
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