Gold nanoparticles - 15nm diameter, methyl terminated, PEG 2000 coated, OD 50, dispersion in H₂O

Cat. No.: G486030

GRADE & PURITY 15nm diameter, methyl terminated, PEG 2000 coated, OD 50, dispersion in H₂O

Synonyms

Au NP OMe, Gold nanoparticles OMe terminated, Gold Colloid

Storage

Store at 2-8°C

Shipped In

Wet ice

Vue d’ensemble

Description

Gold nanoparticles (AuNPs) ranging from 2-200nm in diameter find applications in diverse fields.They show excellent biocompatibility and attractive physicochemical properties. Poly (ethylene) glycol (PEG) surface coatings on gold nanoparticles help in the reduction of protein adsorption, reduce nonspecific interactions with cells and greatly improve the pharmokinetics of these nanoparticles and reduce aggregation of the nanoparticles. PEG layer density depends inversely on the AuNP curvature. Denser coatings are possible on smaller AuNPs. The methyl group, being hydrophobic, acts as a protecting shield between the gold nanoparticles and the hydrophilic outer PEG coating and also leads to a further reduction of protein adsorption and macrophage uptake by the AuNPs.Several other specific applications have been listed below:Since they adhere to cell membranes, AuNPs may find use in cellular and intracellular targeting in targeted drug delivery applications and may also used in biodistribution studies.AuNPs may also be used in photothermal therapy and radiotherapy.AuNPs ranging from 10 to 250 nm, were studied to have been absorbed primarily by liver and spleen , when injected intravenously in rats.Whereas, 10 nm nanoparticles were distributed more broadly into various organs.Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Specifications

Synonymes

Au NP OMe, Gold nanoparticles OMe terminated, Gold Colloid

Spécifications et pureté

15nm diameter, methyl terminated, PEG 2000 coated, OD 50, dispersion in H₂O

Conditions de stockage de stockage

Store at 2-8°C

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Propriétés chimiques et physiques

• Solubilité: water: miscible