Guanidine thiocyanate solution - UltraBio™,Suitable for molecular biology,~6 M in H2O , CAS No.593-84-0

CAS: 593-84-0 Cat. No.: G755743 Formule: C₂H₆N₄S Poids moléculaire: 118.16 Beilstein Registry Number: 3563461 Numéro CE: 209-812-1

GRADE & PURITY UltraBio™, Suitable for molecular biology, ~6 M in H2O

Storage

Room temperature

Shipped In

Normal

Vue d’ensemble

Guanidine thiocyanate is a chaotropic agent that functions as a strong protein denaturant. It is widely used in RNA isolation protocols. Guanidine thiocyanate can irreversibly inactivate RNase and DNase and breaks cellular membranes. It dissolves proteins by disturbing their secondary structures. Guanidine thiocyanate also separates nucleoproteins from nucleic acids and aids the digestion of the proteins with proteases. It improves the activity of proteinase K thus making it the protease of choice.

Application:

Guanidine thiocyanate solution has been used to extract:

• plasma RNA from human immunodeficiency virus (HIV)-infected and control patients
• total RNA from collected tissues (shoots, flowers, fruits, and seeds)
• in reverse transcription-polymerase chain reaction (RT-PCR) analysis, RNA from teratocarcinoma cell line (Tera-1)

Specifications

Spécifications et pureté

UltraBio™,Suitable for molecular biology,~6 M in H2O

Conditions de stockage de stockage

Room temperature

Expédié en

Normal

Grade

Suitable for molecular biology, UltraBio™

Noms et identifiants

PH

4.5-7.0 (25 °C)

Sourires canoniques

C(#N)S.C(=N)(N)N

IUPAC Name

guanidine;thiocyanic acid

InChIKey

ZJYYHGLJYGJLLN-UHFFFAOYSA-N

INCHI

1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H

Isomères SMILES

C(#N)S.C(=N)(N)N

WGK Allemagne

2

RTECS

XL1225000

Numéro ONU

1759

Groupe d'emballage

III

Poids moléculaire

118.16

Beilstein

3563461

Reaxy-Rn

3563461

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3563461&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organosulfur compounds
    • Classe Thiocyanates

• Kingdom: Organic compounds
• Superclass: Organosulfur compounds
• Classe: Thiocyanates
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Thiocyanates
• Alternative Parents: Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Thiocyanate - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as thiocyanates. These are salts or esters of thiocyanic acid, with the general formula RSC#N (R=alkyl, aryl).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Point de fusion (°C): 118-122°C
• Poids moléculaire: 118.160 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 118.031 Da
• Monoisotopic Mass: 118.031 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 57.600
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3