HX531 - Moligand™, 10 mM in DMSO , CAS No.188844-34-0

CAS: 188844-34-0 Cat. No.: H1494130 Formule: C₂₉H₂₉N₃O₄ Poids moléculaire: 483.56

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

HX531 is an effective RXR antagonist with oral activity, with an IC 50 of 18 nM, with activity against black melanoma. HC531 can eliminate the anti- apoptotic effects of all-trans-retinoic acid (t-RA) and exerts anti-obesity and anti-diabetic effects through leptin-dependent pathways and the p53-p21Cip1 pathway, resulting in G0/G1 cell cycle arrest.

Specifications

Spécifications et pureté

Moligand™, 10 mM in DMSO

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

ACTIVATOR

Noms et identifiants

Isomères SMILES

CC1(CCC(C2=C1C=C3C(=C2)N(C4=C(C=C(C=C4)[N+](=O)[O-])N=C3C5=CC=C(C=C5)C(=O)O)C)(C)C)C

Poids moléculaire

483.56

Reaxy-Rn

8522214

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8522214&ln=