10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Protected from light,Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vue d’ensemble
Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC 50 of 9.8 nM for RGD-binding α4β1 . Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC 50 of 12.9 nM
In Vitro
Integrin modulator 1 (2-10 μg/mL; 30 min) significantly increases Jurkat E6.1 cell adhesion. Integrin modulator 1 (1-100 nM; 1 h) strongly and significantly increases ERK1/2 phosphorylation in Jurkat E6.1 cells. Integrin modulator 1 (1 nM-10 μM; 30 min) significantly increases the binding of HUTS-21 antibody to Jurkat E6.1 cells in a concentration-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:α4β1 9.8 nM (IC 50 )
Specifications
Spécifications et pureté
10mM in DMSO
Mécanismes biochimiques et physiologiques
Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC 50 of 9.8 nM for RGD-binding α4β1 . Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC 50 of 12.9 nM.
Conditions de stockage de stockage
Protected from light,Desiccated,Store at -80°C
Expédié en
Dry ice packs + Cold packs
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
AGONIST
Noms et identifiants
Isomères SMILES
CC1=CC=CC=C1NC(=O)N2C(CC2=O)CC(=O)O
PubChem CID
154734317
Poids moléculaire
262.26
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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