KKII5 - Moligand™,≥98% , CAS No.6381-55-1

CAS: 6381-55-1 Cat. No.: K649315 Formule: C₁₆H₁₄N₂S Poids moléculaire: 266.36 PubChem CID: 2725891

GRADE & PURITY Moligand™, ≥98%

Synonyms

4,6-Diphenyl-1,2,3,4-Tetrahydropyrimidine-2-Thione | 4,6-Diphenyl-3,4-dihydropyrimidine-2(1H)-thione

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

KKII5 is a potent Lipoxygenase ( LOX-1 ) inhibitor with an IC 50 of 19 μM. KKII5 inhibits lipid peroxidation

In Vitro

KKII5 interacts with HIS499 of the cavity by forming one π–π stacking interaction between the phenyl ring of the molecule and the imidazole ring of HIS499. KKII5 (100 μM) strongly inhibits lipid peroxidation with 98% inhibition. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 19 μM (LOX-1)

Specifications

Synonymes

4,6-Diphenyl-1,2,3,4-Tetrahydropyrimidine-2-Thione | 4,6-Diphenyl-3,4-dihydropyrimidine-2(1H)-thione

Spécifications et pureté

Moligand™,≥98%

Mécanismes biochimiques et physiologiques

KKII5 is a potent Lipoxygenase ( LOX-1 ) inhibitor with an IC 50 of 19 μM. KKII5 inhibits lipid peroxidation.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

INHIBITOR

Pureté

≥98%

Noms et identifiants

Isomères SMILES

C1=CC=C(C=C1)C2C=C(NC(=S)N2)C3=CC=CC=C3

PubChem CID

2725891

Poids moléculaire

266.36

Propriétés chimiques et physiques

• Poids moléculaire: 266.400 g/mol
• XLogP3: 3.300
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 266.088 Da
• Monoisotopic Mass: 266.088 Da
• Topological Polar Surface Area: 56.200 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 352.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 6381-55-1, the molecular formula is C16H14N2S, and the molecular weight is 266.36 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.