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KKII5 - Moligand™,≥98% , CAS No.6381-55-1

CAS: 6381-55-1 Cat. No.: K649315 Molecular Weight: 266.36 PubChem CID: 2725891
COA
KKII5 - ≥98% CAS No(6381-55-1) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
4,6-Diphenyl-1,2,3,4-Tetrahydropyrimidine-2-Thione | 4,6-Diphenyl-3,4-dihydropyrimidine-2(1H)-thione
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
K649315-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
5mg
K649315-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
25mg
K649315-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$129.90
100mg
K649315-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
250mg
K649315-250mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$499.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

KKII5 is a potent Lipoxygenase ( LOX-1 ) inhibitor with an IC 50 of 19 μM. KKII5 inhibits lipid peroxidation

In Vitro

KKII5 interacts with HIS499 of the cavity by forming one π–π stacking interaction between the phenyl ring of the molecule and the imidazole ring of HIS499. KKII5 (100 μM) strongly inhibits lipid peroxidation with 98% inhibition. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 19 μM (LOX-1)

Specifications

Synonyms
4, 6-Diphenyl-1, 2, 3, 4-Tetrahydropyrimidine-2-Thione | 4, 6-Diphenyl-3, 4-dihydropyrimidine-2(1H)-thione
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
KKII5 is a potent Lipoxygenase ( LOX-1 ) inhibitor with an IC 50 of 19 μM. KKII5 inhibits lipid peroxidation.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Purity
≥98%
Names and Identifiers
Isomeric SMILES C1=CC=C(C=C1)C2C=C(NC(=S)N2)C3=CC=CC=C3
PubChem CID 2725891
Molecular Weight 266.36

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Molecular Weight266.400 g/mol
XLogP33.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass266.088 Da
Monoisotopic Mass266.088 Da
Topological Polar Surface Area56.200 Ų
Heavy Atom Count19
Formal Charge0
Complexity352.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →
Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

View related series

Lipid Metabolism (5004) Lipoxygenase (57) Metabolic Enzyme/Protease (4867)
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