Monoolein - Moligand™, ≥95% , Agonist of GPR119, CAS No.111-03-5, Agonist of GPR119

CAS: 111-03-5 Cat. No.: M395915 Formule: C₂₁H₄₀O₄ Poids moléculaire: 356.54 Beilstein Registry Number: 1728976 Numéro CE: 203-827-7

QUALITÉ & PURETÉ Moligand™, ≥95%

Synonyms

1-Oleylglycerol | alpha-Monoolein | Excel O 95F | Oleoyl glycerol | 1-Monooleoyl-rac-glycerol | CHEBI:75342 | Emery oleic acid ester 2221 | Nikkol MGO | rac-1-Monoolein | Monoolein | mono-olein | 1,2,3-propanetriol mono((Z)-9-octadecenoate) | 2,3-dihydrox

Storage

Stocker à -20°C, chargé d'argon

Shipped In

Glacière + blocs de glace

Vue d’ensemble

le 1-Oleoyl-rac-glycérol est un monoglycéride, obtenu à partir d'huiles et de graisses naturelles. Il contient deux groupes d'alcool réactifs. Il est soluble dans le chloroforme et l'hexane. Il peut être cristallisé à partir de l'hexane.

Spécifications

Synonymes

1-Oleylglycerol | alpha-Monoolein | Excel O 95F | Oleoyl glycerol | 1-Monooleoyl-rac-glycerol | CHEBI:75342 | Emery oleic acid ester 2221 | Nikkol MGO | rac-1-Monoolein | Monoolein | mono-olein | 1,2,3-propanetriol mono((Z)-9-octadecenoate) | 2,3-dihydrox

Spécifications et pureté

Moligand™, ≥95%

Mécanismes biochimiques et physiologiques

le 1-Oleoyl-rac-glycérol montre une action à la fois inhibitrice et anti-inhibitrice sur l'hydrolyse des triglycérides médiée par la lipoprotéine lipase.

Conditions de stockage de stockage

Stocker à -20°C, chargé d'argon

Expédié en

Glacière + blocs de glace

Grade

Moligand™

Type d'action

AGONIST

Mécanisme d'action

Agonist of GPR119

Pureté

≥95%

Noms et identifiants

Pubchem Sid

528773364

Sourires canoniques

CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)O

IUPAC Name

2,3-dihydroxypropyl (Z)-octadec-9-enoate

InChIKey

RZRNAYUHWVFMIP-KTKRTIGZSA-N

INCHI

1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

Isomères SMILES

CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)O

WGK Allemagne

1

CAS alternatif

25496-72-4

Poids moléculaire

356.54

Beilstein

1728976

Reaxy-Rn

1728976

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1728976&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Classe Glycerolipids
      • Subclass Monoradylglycerols
        • Level5 Monoacylglycerols
          • Level6 1-monoacylglycerols

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Classe: Glycerolipids
• Subclass: Monoradylglycerols
• Intermediate Tree Nodes: Monoacylglycerols
• Direct Parent: 1-monoacylglycerols
• Alternative Parents: Fatty acid esters Secondary alcohols Carboxylic acid esters 1,2-diols Monocarboxylic acids and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: 1-acyl-sn-glycerol - Fatty acid ester - Fatty acyl - 1,2-diol - Carboxylic acid ester - Secondary alcohol - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Primary alcohol - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Alcohol - Organic oxide - Organooxygen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as 1-monoacylglycerols. These are monoacylglycerols containing a glycerol acylated at the 1-position.
• External Descriptors: Monoacylglycerols

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

GPR119 Tclin Glucose-dependent insulinotropic receptor (1 Activities)

Discover Target: GPR119

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

Discover Target: PTGS2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G2A Tchem Phospholipase A2 group IIA (1079 Activities)

Discover Target: PLA2G2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Sensibilité: light sensitive;air sensitive ;Moisture sensitive.
• Point d'éclair (°F): 309.2 °F
• Point d'éclair (°C): 154 °C
• Point de fusion (°C): 35-37°C
• Poids moléculaire: 356.500 g/mol
• XLogP3: 6.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 19
• Exact Mass: 356.293 Da
• Monoisotopic Mass: 356.293 Da
• Topological Polar Surface Area: 66.800 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 315.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1