N-Nitrosodimethylamine - ≥99% , CAS No.62-75-9

CAS: 62-75-9 Cat. No.: N396014 Molecular Weight: 74.08 EC Number: 200-549-8

GRADE & PURITY ≥99%

Synonyms

N-NITROSODIMETHYLAMINE|Dimethylnitrosamine|62-75-9|NDMA|N-Methyl-N-nitrosomethanamine|Dimethylnitrosoamine|N,N-Dimethylnitrosamine|DMNA|Nitrosodimethylamine|N,N-dimethylnitrous amide|Methanamine, N-methyl-N-nitroso-|Dimethylnitrosamin|N-Nitroso-N,N-dimeth

Storage

Room temperature,Argon charged

Shipped In

FedEx DG Service

Specifications

Synonyms

N-NITROSODIMETHYLAMINE | Dimethylnitrosamine | 62-75-9 | NDMA | N-Methyl-N-nitrosomethanamine | Dimethylnitrosoamine | N, N-Dimethylnitrosamine | DMNA | Nitrosodimethylamine | N, N-dimethylnitrous amide | Methanamine, N-methyl-N-nitroso- | Dimethylnitrosamin | N-Nitroso-N, N-dimeth

Specifications & Purity

≥99%

Storage

Room temperature, Argon charged

Shipped In

FedEx DG Service

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 488180010
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488180010
• Canonical Smiles: CN(C)N=O
• IUPAC Name: N,N-dimethylnitrous amide
• InChIKey: UMFJAHHVKNCGLG-UHFFFAOYSA-N
• INCHI: 1S/C2H6N2O/c1-4(2)3-5/h1-2H3
• Isomeric SMILES: CN(C)N=O
• WGK Germany: 3
• RTECS: IQ0525000
• UN Number: 2810
• Packing Group: I
• Molecular Weight: 74.08
• Reaxy-Rn: 1738979
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1738979&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Organic nitroso compounds

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Organic nitroso compounds
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic N-nitroso compounds
• Alternative Parents: Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organic n-nitroso compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as organic n-nitroso compounds. These are organic compounds containing a n-nitroso group -NN=O.
• External Descriptors: nitrosamine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water, alcohol and ether
• Sensitivity: Air sensitive
• Refractive Index: 1.44
• Flash Point(°C): 61 °C
• Boil Point(°C): 153°C
• Molecular Weight: 74.080 g/mol
• XLogP3: -0.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 74.048 Da
• Monoisotopic Mass: 74.048 Da
• Topological Polar Surface Area: 32.700 Ų
• Heavy Atom Count: 5
• Formal Charge: 0
• Complexity: 34.600
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Zhiqin Ding, Mengdie Cai, Weimin Gan, Ping Yuan, Lijun Wei, Xianglei Cheng.  (2022)  Studies on a novel method for the determination of nitrosamines in food by HPLC-UV-FLD coupling with terbium-doped carbon dots.  FOOD CHEMISTRY,      [PMID:] [10.1016/j.foodchem.2022.134894]

2. Yuanan Hu, Yuanzhen He, Hefa Cheng.  (2017)  Microwave-induced degradation of N-nitrosodimethylamine (NDMA) sorbed in zeolites: Effect of mineral surface chemistry and non-thermal effect of microwave.  Journal of Cleaner Production,      [PMID:] [10.1016/j.jclepro.2017.11.014]

3. Kaili Huang, Haiqing Huang, Xuhui Huang, An Lao, Zheng Zheng, Hanqi Wu.  (2024)  Combined Toxic Effects and Mechanisms of Chloroacetic Acid and N-Nitrosodimethylamine on Submerged Macrophytes.  Water,  16  (18): (2689).  [PMID:] [10.3390/w16182689]

4. Qing Bai, Qian-Yuan Wu, Yun-peng Wu, Yu-jia Nong, Zi-Bo Jing, Min-Yong Lee, Wen-Long Wang.  (2025)  Distinct effects of inorganic and organic carbon on nitrate photolysis and micropollutant degradation under Far-UVC (222 nm) irradiation.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:41167165] [10.1016/j.jhazmat.2025.140274]

5. Wenxin Wang, Shuhua Xi, Yue Wang.  (2026)  N-nitrosodimethylamine increased glucose production by promoting hyperglycemia in hepatocyte via AMPK signaling pathway in vivo and in vitro.  DRUG AND CHEMICAL TOXICOLOGY,      [PMID:41483025] [10.1080/01480545.2025.2609950]

6. Menglan Gao, Tingting Zhao, Xiaobin Liao, Tao Huan, Qiming Shen, K. N. Minh Chau, Di Zhang, Zhenkun Chen, Huatong Ma, Xing-Fang Li.  (2026)  Data-Driven Discovery of Unknown Precursors of N-Nitrosodimethylamine in Nontargeted Liquid Chromatography–High Resolution Mass Spectrometry Analysis.  ENVIRONMENTAL SCIENCE & TECHNOLOGY,      [PMID:41714108] [10.1021/acs.est.5c10336]