Nestoron - ≥97%(HPLC) , Progesterone receptor agonist, CAS No.7759-35-5, Progesterone receptor agonist

CAS: 7759-35-5 Cat. No.: N126972 Formule: C₂₃H₃₀O₄ Poids moléculaire: 370.48 Numéro CE: 643-056-7 PubChem CID: 108059

GRADE & PURITY ≥97%(HPLC)

Synonyms

Nestorone | Acétate de ségestérone | (8R,9S,10R,13S,14S,17R)-17-acétyl-13-méthyl-16-méthylène-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate | 17-acetyl-13-methyl-16-methylene-3-oxo-2,3,6,7,8,9,10,11,12,

Storage

Conserver à -20°C

Shipped In

Glacière + blocs de glace

Vue d’ensemble

Nestoron (ST-1435) est un dérivé de la 19-norprogestérone présentant une affinité et une sélectivité élevées pour les récepteurs de la progestérone. Nestoron est un progestatif puissant et hautement sélectif.

Specifications

Synonymes

Nestorone | Acétate de ségestérone | (8R,9S,10R,13S,14S,17R)-17-acétyl-13-méthyl-16-méthylène-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate | 17-acetyl-13-methyl-16-methylene-3-oxo-2,3,6,7,8,9,10,11,12,

Spécifications et pureté

≥97%(HPLC)

Mécanismes biochimiques et physiologiques

Nestoron (Elcometrine ; Nestorone ; ST-1435) est un progestatif synthétique.

Conditions de stockage de stockage

Conserver à -20°C

Expédié en

Glacière + blocs de glace

Type d'action

AGONIST

Mécanisme d'action

Progesterone receptor agonist

Pureté

≥97%(HPLC)

Propriétés du produit

• ALogP: 2.9

Noms et identifiants

• Pubchem Sid: 528776010
• Sourires canoniques: CC(=O)C1(C(=C)CC2C1(CCC3C2CCC4=CC(=O)CCC34)C)OC(=O)C
• IUPAC Name: [(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylidene-3-oxo-2,6,7,8,9,10,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
• InChIKey: CKFBRGLGTWAVLG-GOMYTPFNSA-N
• INCHI: 1S/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1
• Isomères SMILES: CC(=O)[C@]1(C(=C)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@H]34)C)OC(=O)C
• WGK Allemagne: 3
• PubChem CID: 108059
• Poids moléculaire: 370.48

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Classe Steroids and steroid derivatives
      • Subclass Pregnane steroids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Classe: Steroids and steroid derivatives
• Subclass: Pregnane steroids
• Intermediate Tree Nodes: Not available
• Direct Parent: Gluco/mineralocorticoids, progestogins and derivatives
• Alternative Parents: Steroid esters 20-oxosteroids 3-oxo delta-4-steroids Delta-4-steroids Cyclohexenones Alpha-acyloxy ketones Carboxylic acid esters Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Progestogin-skeleton - Steroid ester - 20-oxosteroid - 3-oxo-delta-4-steroid - 3-oxosteroid - Oxosteroid - Delta-4-steroid - Cyclohexenone - Alpha-acyloxy ketone - Carboxylic acid ester - Cyclic ketone - Ketone - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organic oxide - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organooxygen compound - Aliphatic homopolycyclic compound
• Description: This compound belongs to the class of organic compounds known as gluco/mineralocorticoids, progestogins and derivatives. These are steroids with a structure based on a hydroxylated prostane moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Solubilité: DMSO
• Sensibilité: Moisture sensitive.
• Poids moléculaire: 370.500 g/mol
• XLogP3: 2.900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 370.214 Da
• Monoisotopic Mass: 370.214 Da
• Topological Polar Surface Area: 60.400 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 762.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 6
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1