Determine the necessary mass, volume, or concentration for preparing a solution.
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature,Desiccated,Cool Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 47 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 488184223 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488184223 |
| Canonical Smiles | C1=CC(=C(C=C1C(=O)O)[N+](=O)[O-])C(=O)O |
| IUPAC Name | 2-nitroterephthalic acid |
| InChIKey | QUMITRDILMWWBC-UHFFFAOYSA-N |
| INCHI | 1S/C8H5NO6/c10-7(11)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3H,(H,10,11)(H,12,13) |
| Isomeric SMILES | C1=CC(=C(C=C1C(=O)O)[N+](=O)[O-])C(=O)O |
| WGK Germany | 3 |
| Molecular Weight | 211.13 |
| Beilstein | 1913840 |
| Reaxy-Rn | 1913836 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1913836&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Benzoic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Nitrobenzoic acids and derivatives |
| Alternative Parents | P-phthalic acid and derivatives Nitrobenzenes Benzoic acids Nitroaromatic compounds Benzoyl derivatives Dicarboxylic acids and derivatives Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Carboxylic acids Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Nitrobenzoate - Para_phthalic_acid - Benzoic acid - Nitrobenzene - Nitroaromatic compound - Benzoyl - Dicarboxylic acid or derivatives - C-nitro compound - Organic nitro compound - Allyl-type 1,3-dipolar organic compound - Organic oxoazanium - Carboxylic acid - Carboxylic acid derivative - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as nitrobenzoic acids and derivatives. These are compounds containing a nitrobenzoic acid moiety, which consists of a benzene ring bearing both a carboxylic acid group and a nitro group on two different ring carbon atoms. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 02, 2026 | N159455 | |
| Certificate of Analysis | Feb 02, 2026 | N159455 | |
| Certificate of Analysis | Feb 02, 2026 | N159455 | |
| Certificate of Analysis | Feb 02, 2026 | N159455 | |
| Certificate of Analysis | May 10, 2025 | N159455 | |
| Certificate of Analysis | May 10, 2025 | N159455 | |
| Certificate of Analysis | May 10, 2025 | N159455 | |
| Certificate of Analysis | May 10, 2025 | N159455 | |
| Certificate of Analysis | May 10, 2025 | N159455 | |
| Certificate of Analysis | May 10, 2025 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Nov 19, 2022 | N159455 | |
| Certificate of Analysis | Dec 06, 2021 | N159455 | |
| Certificate of Analysis | Dec 06, 2021 | N159455 | |
| Certificate of Analysis | Dec 06, 2021 | N159455 | |
| Certificate of Analysis | Dec 06, 2021 | N159455 | |
| Certificate of Analysis | Dec 06, 2021 | N159455 |
| Melt Point(°C) | 270-272°C |
|---|---|
| Molecular Weight | 211.130 g/mol |
| XLogP3 | 1.000 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 211.012 Da |
| Monoisotopic Mass | 211.012 Da |
| Topological Polar Surface Area | 120.000 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 296.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Xinzhao Jiang, Wei Wang, Jincheng Tang, Meng Han, Yichang Xu, Lichen Zhang, Jie Wu, Yiyang Huang, Zhouye Ding, Huiwen Sun, Kun Xi, Yong Gu, Liang Chen. (2023) Ligand-Screened Cerium-Based MOF Microcapsules Promote Nerve Regeneration via Mitochondrial Energy Supply. Advanced Science, [PMID:38037294] [10.1002/advs.202306780] |
| 2. Cong Li, Chang Li, Le Sun, Pushuang Xing, Ronglan Zhang. (2023) Three-layer coated composite materials PMoV2@UiO-66-X@mSiO2: Efficient oxidative desulfurization catalysts. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, [PMID:] [10.1016/j.jiec.2023.11.051] |
| 3. Qiuyun Zhang, Yaping Wu, Xingyue Hong, Zhenying Li, Yanting Lei, Rongfei Yu, Taoli Deng, Yutao Zhang, Peihua Ma. (2023) Different ligand functionalized bimetallic (Zr/Ce)UiO-66 as a support for immobilization of phosphotungstic acid with enhanced activity for the esterification of fatty acids. Sustainable Chemistry and Pharmacy, [PMID:] [10.1016/j.scp.2023.101344] |
| 4. Yongzhao Zhang, Xuzheng Chen, Zhenya Zhu, Luping Lv. (2023) Transformation of glucose to 5-hydroxymethylfurfural with Al and Sn mixed-metal metal–organic frameworks as catalyst. APPLIED ORGANOMETALLIC CHEMISTRY, [PMID:] [10.1002/aoc.7310] |
| 5. Junxue Liu, Wenyan Ma, Yufei Wang, Qinfen Gu, Qinhe Pan, Siyu Zong, Minghao Qin, Jiyang Li. (2023) Enhanced oxidase-mimic constructed by luminescent carbon dots loaded on MIL-53(Fe)-NO2 for dual-mode detection of gallic acid and biothiols in food and humans. FOOD CHEMISTRY, [PMID:37660599] [10.1016/j.foodchem.2023.137241] |
| 6. Jun Wang, Junxian Qin, Changqing Yang, Yun Hu. (2023) Effect of ligand substitution in UiO-66 metal-organic frameworks on the photocatalytic oxidation of acetaldehyde. CHEMOSPHERE, [PMID:37597629] [10.1016/j.chemosphere.2023.139841] |
| 7. Ping Li, Zhengyang Gu, Chengling Bai, Ying Xu, Jingwen Tang, Junying Ren, Longqian Xu, Shuili Yu. (2023) Effects of MOFs size and functional group on the pore structure and performance of thin-film nanocomposite membranes. JOURNAL OF MEMBRANE SCIENCE, [PMID:] [10.1016/j.memsci.2023.121979] |
| 8. Jianhong Zheng, Xi Chen, Xiaoxiao Yin, Kai Chen, Aili Liu, Xiaochun Yu, Shun Wang, Zhongwei Chen. (2023) Zr-MOF catalyzed selective oxidation of anilines to azoxybenzenes in aqueous H2O2 solution. Molecular Catalysis, [PMID:] [10.1016/j.mcat.2023.113420] |
| 9. Ya Wang, Yuanhua Wei, Siqi Li, Guang Hu. (2023) A Nitro Functionalized MOF with Multi-Enzyme Mimetic Activities for the Colorimetric Sensing of Glucose at Neutral pH. SENSORS, 23 (14): (6277). [PMID:37514570] [10.3390/s23146277] |
| 10. Hong Zhang, Yuanfei Zhang, Yiyang Li, Min Hu, Zihan Rong, Lingjie Meng, Xiaofei Zhang, Luan Wen, Xiumin Liang, Zhaopeng Chen, Chengcheng Liu. (2023) A Novel Silver Nanoparticles-Decorated Metal-Organic Framework with Rapid and Sustained Antimicrobial Activity against Drug-Resistant Candida albicans through Synergistic Chemodynamic and Sonodynamic Therapy. Advanced Therapeutics, [PMID:] [10.1002/adtp.202300074] |
| 11. Di Zhang, Hao Tang, Bing Zhao, Lijie Liu, Hongwei Pang, Xiangxue Wang, Shujun Yu. (2023) Immobilization of uranium by S-NZVI and UiO-66-NO2 composite through combined adsorption and reduction. Journal of Cleaner Production, [PMID:] [10.1016/j.jclepro.2023.136149] |
| 12. Penghao Zhu, Zaka Ullah, Surong Zheng, Zairui Yang, Shiwei Yu, Shoupu Zhu, Liwei Liu, Aihua He, Cunguo Wang, Qi Li. (2023) Ultrahigh current output from triboelectric nanogenerators based on UIO-66 materials for electrochemical cathodic protection. Nano Energy, [PMID:] [10.1016/j.nanoen.2023.108195] |
| 13. Qiufan Sun, Yuxiang Zhu, Xiang Zhong, Meng Jiang, Yanchen Fan, Jianfeng Yao. (2022) Tuning Photoactive MIL-68(In) by Functionalized Ligands for Boosting Visible-Light Nitrogen Fixation. ACS Applied Materials & Interfaces, [PMID:36416066] [10.1021/acsami.2c17007] |
| 14. Jiayou Liu, Xiaoxiang Huang, Linfeng Liu, Qianqian Nie, Zhongchao Tan, Hesheng Yu. (2022) New insights into the removal of nitric oxide using UiO-66-NH2: Synergistic photooxidation and subsequent adsorption. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2022.108294] |
| 15. Xiuling Zhang, Xiaoke Hao, Zhenyu Zhai, Jiaona Wang, Huiyu Li, Yaxin Sun, Yue Qin, Ben Niu, Congju Li. (2021) Flexible H2S sensors: Fabricated by growing NO2-UiO-66 on electrospun nanofibers for detecting ultralow concentration H2S. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2021.151446] |
| 16. Weixia Yang, Jinmeng Wang, Yong Han, Xueli Luo, Wenzhi Tang, Tianli Yue, Zhonghong Li. (2021) Robust MOF film of self-rearranged UiO-66-NO2 anchored on gelatin hydrogel via simple thermal-treatment for efficient Pb(II) removal in water and apple juice. FOOD CONTROL, [PMID:] [10.1016/j.foodcont.2021.108409] |
| 17. Xingchang Tang, Yongwei Luo, Zhijian Zhang, Wanwu Ding, Dexue Liu, Jingchuan Wang, Li Guo, Ming Wen. (2021) Effects of functional groups of –NH2 and –NO2 on water adsorption ability of Zr-based MOFs (UiO-66). CHEMICAL PHYSICS, [PMID:] [10.1016/j.chemphys.2021.111093] |
| 18. Jiayan Wang, Wenying Li, Yue-Qing Zheng. (2020) Colorimetric assay for the sensitive detection of phosphate in water based on metal–organic framework nanospheres possessing catalytic activity. NEW JOURNAL OF CHEMISTRY, 44 (45): (19683-19689). [PMID:] [10.1039/D0NJ04164E] |
| 19. Xu Weiqing, Kang Yikun, Jiao Lei, Wu Yu, Yan Hongye, Li Jinli, Gu Wenling, Song Weiyu, Zhu Chengzhou. (2020) Tuning Atomically Dispersed Fe Sites in Metal–Organic Frameworks Boosts Peroxidase-Like Activity for Sensitive Biosensing. Nano-Micro Letters, 12 (1): (1-12). [PMID:34138213] [10.1007/s40820-020-00520-3] |
| 20. Yong-Jun Chen, Yifa Chen, Chang Miao, Yi-Rong Wang, Guang-Kuo Gao, Ru-Xin Yang, Hong-Jing Zhu, Jian-Hui Wang, Shun-Li Li, Ya-Qian Lan. (2020) Metal–organic framework-based foams for efficient microplastics removal. Journal of Materials Chemistry A, 8 (29): (14644-14652). [PMID:] [10.1039/D0TA04891G] |
| 21. Zhen Li, Songjian Zhao, Huizhen Wang, Ying Peng, Zhijie Tan, Bin Tang. (2019) Functional groups influence and mechanism research of UiO-66-type metal-organic frameworks for ketoprofen delivery. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:30822680] [10.1016/j.colsurfb.2019.02.027] |
| 22. Wang Ying, Wang Xu, Liu Ziyun, Dong Fangdi, Lin Yuqing. (2024) Ce-MOFs Fluorescent Probes with Different Ligands for Phosphate Detection. Journal of Analysis and Testing, [PMID:] [10.1007/s41664-024-00325-y] |
| 23. Wei Sun, Jiale Lu, Bo Feng, Amin Jv, Yufei Zhang, Jingwen Wang, Renquan Guan, Chunbo Liu. (2025) Constructing amide bond carrier transport channels to effectively enhance visible light catalyzed degradation of tetracycline. Surfaces and Interfaces, [PMID:] [10.1016/j.surfin.2025.105983] |
| 24. Long Chen, Miao Li, Ying Yang, Xiaoqing Qiu. (2024) Electronic tuning of platinum cocatalysts over g-C3N4 nanosheets through the linker engineering for photocatalytic hydrogen evolution. CHEMOSPHERE, [PMID:39638123] [10.1016/j.chemosphere.2024.143895] |
| 25. Xiaoguang Zhu, Jiaqi Xu, Yuanke Zhang, Guixia Ling, Peng Zhang. (2024) Engineered nanozymes for speedy colorimetric biosensing and sensitive cascaded-catalytic determining of norfloxacin. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2024.159981] |
| 26. Mengting Xu, Zeyu Chen, Yeyang Ni, Wanyong Yang, Xihua Xu, Qing Liu, Zhaoyang Fei, Mifen Cui, Xu Qiao. (2024) Enhancement tetracycline adsorption by amino/nitro-functionalized MIL-126(Fe) adsorbent based on the ligand installation method. MICROPOROUS AND MESOPOROUS MATERIALS, [PMID:] [10.1016/j.micromeso.2024.113228] |
| 27. Ke Wu, Zhimin Yang, Sen Liu, Xishuang Liang, Teng Fei, Tong Zhang. (2024) Sea urchin inspired ultrafast response low humidity sensor based on ionic liquid modified UiO-66 with advanced applications. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:38986319] [10.1016/j.jcis.2024.07.048] |
| 28. Yongjie Zhu, Ruirui Wang, Yongquan Zhou, Wanxia Ma, Jie Fan, Xiaochuan Deng, Chaoliang Zhu, Aimin Yu, Guowang Xu, Dong-Sheng Li, Chenghua Sun. (2025) Sulfonate-functionalized MIL-101 with high lithium adsorption capacity and selectivity. Materials Today Energy, [PMID:] [10.1016/j.mtener.2025.101817] |
| 29. Ming Ruan, Huajing Zhou, Lingxiang Zhao, Tianding Hu, Liang He, Shaoyun Shan. (2024) The ortho-substituent effect regulating the separation of photogenerated carriers to efficiently photodegrade tetracycline on the surface of FeCo-based MOFs. CHEMOSPHERE, [PMID:38296214] [10.1016/j.chemosphere.2024.141296] |
| 30. Ying Zhou, Xiao-Tong Song, Hui-Chao Guan, Shu-Mei Yue. (2024) Zn(II), Cd(II), Mn(II), and Cu(II) complexes based on an imidazole derivative and carboxylic acids: synthesis, crystal structures, and DNA-binding properties. JOURNAL OF COORDINATION CHEMISTRY, [PMID:] [10.1080/00958972.2024.2311715] |
| 31. Mingjun Xie, Yuying Han, Na Wang, Zixuan Huang, Congting Sun. (2025) Enhanced activation of PMS via Fe-MOFs-derives@BC for efficient removal of dyes: Complementary between radical and nonradical pathways. Journal of Water Process Engineering, [PMID:] [10.1016/j.jwpe.2025.108426] |
| 32. Xiao Ling, Xiaofeng Guo, Ke Wang, Ziming Huang, Zhixuan Mo, Huibo Qin, Linhai Duan, Xiuhong Meng, Hui Wang. (2025) Synthesis and application of UiO-66-NO2@Ag/AgCl nanocomposite as photocatalysts for water remediation. Surfaces and Interfaces, [PMID:] [10.1016/j.surfin.2025.107416] |
| 33. Yuhang Shen, Ziyi Mi, Xiaoya Hu, Yun Shu. (2025) Fully integrated wearable microfluidic device for molecularly imprinted electrochemical and cascade catalysis colorimetric analysis of cortisol and glucose in sweat. BIOSENSORS & BIOELECTRONICS, [PMID:41032973] [10.1016/j.bios.2025.118050] |
| 34. YinZuo Wu, Guoqian Xu, HaiBang Zhang, Ziyue Fu, Hedong Jiang, Pingchun Guo, Yanxiang Wang, Shijin Yu, Hua Zhu. (2025) A high ionic conductivity composite polymer solid electrolyte based on UiO-66 modified with -NH2. ELECTROCHIMICA ACTA, [PMID:] [10.1016/j.electacta.2025.147355] |
| 35. Chen Chen, Liang Zhigang, Li Xinyang, Xu Feifei, Xu Guanhong, Wei Fangdi, Yang Jing, Hu Qin, Cen Yao. (2024) A metal–organic framework and quantum dot-based ratiometric fluorescent probe for the detection of formaldehyde in food. MICROCHIMICA ACTA, 191 (5): (1-10). [PMID:38619658] [10.1007/s00604-024-06348-7] |
| 36. Chong Lin, Shan Wang, Xuetong Zhang, Bin Xiao, Yepeng Zeng, Li Huang, Fei Luo, Kangye Liu, Jingyang Tian, Min Li, Minghui Cao, Yong Qian. (2025) Unraveling the Role of Functional Groups of Terephthalate in Enhancing the Electrochemical Oxygen Evolution Reaction of Nickel–Organic Framework Nanoarrays. INORGANIC CHEMISTRY, [PMID:39847755] [10.1021/acs.inorgchem.4c04958] |
| 37. Muhammad Kashif Majeed, Arshad Hussain, Muhammad Akram, M.Umar Majeed, Muhammad Arshad, Adil Saleem, Rashid Iqbal. (2025) Linker-Functionalized Zr-Based UiO-66 Metal-Organic Frameworks: Tuning Acidity for Enhanced Catalytic Dimerization of Cyclohexanone. ChemNanoMat, [PMID:] [10.1002/cnma.202500026] |
| 38. Qiuyun Zhang, Mei Deng, Xingxin Li, Nian Xu, Ting Li, Qing Liu, Zhengjun Liu, Yutao Zhang. (2025) Different Ligand Functionalized Al-Based MOFs as a Support for Impregnation of Heteropoly Acid for Efficient Esterification Reactions. APPLIED ORGANOMETALLIC CHEMISTRY, 39 (6): (e70217). [PMID:] [10.1002/aoc.70217] |
| 39. Bai Yizhuo, Zhang Shiyu, Zhang Kaifan, Li Jiali, Zhang Jiehe, Hao Mingxu, Tao Haisheng. (2025) The Nitro-Modified NO2-MIL-53(Fe) Activating Persulfate for the Efficient Degradation of Tetracycline: Performance and Mechanism. Journal of Inorganic and Organometallic Polymers and Materials, [PMID:] [10.1007/s10904-025-03848-8] |
| 40. Ting Suo, Xiang Shi, Yu Su, Yu Wang, Zhaoxu Wang, Ruirui Yun. (2025) Rational Grafting of Specific Functional Groups to Heterostructured MOF Catalysts for Enhanced Hydrogenation. ACS Applied Materials & Interfaces, [PMID:40553579] [10.1021/acsami.5c09204] |
| 41. Nan Zhang, Pengfei Cui, Jinrong Zhang, Yang Qiao. (2025) MOF-Derived Electrocatalysts for High-Efficiency Hydrogen Production via Water Electrolysis. Catalysts, 15 (6): (579). [PMID:] [10.3390/catal15060579] |
| 42. Feng Tianxu, Shan Wei, Zhang Yongzhou, Huang Haibo, Tang Hua. (2025) S-Scheme Ti@Ce MOF Heterojunction for Enhanced Visible-light Photocatalytic Degradation. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, [PMID:] [10.1007/s40242-025-5119-4] |
| 43. Xiaojuan Hu, Dan Zhang, Hongji Li, Mengyang Xu, Jiaqi Geng, Juan Zhou, Wei Sun. (2025) Tailored UiO-66-X on quartz crystal microbalance for PPB-level toluene detection. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.116251] |
| 44. Jiajing Xia, Binxv Wei, Wenqian Mao, Weizhong Cao, Weizheng Wan, Yuerang Zhang, Dan Xiang, Min Hu. (2025) A portable hydrogel kit coupled with smartphone for point-of-care glucose testing. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.116564] |
| 45. Yao Li, Zaixiao Ren, Juan Bai, Keju Sun, Ziwei Song, Shaotong Song. (2025) Ligand Engineering of UiO-66 for CO2-to-DMC Reaction: Unraveling the Role of Acidity, Defects, and Electronic Effects in Catalytic Performance. Catalysts, 16 (1): (33). [PMID:] [10.3390/catal16010033] |
| 46. Wen Qin, Wenhao Pan, Jialing Zhang, Junyan Tang, Jiming Huang, Mi Tang, Zhengbang Wang. (2026) Modulating the Overall Properties of PEO/NaTFSI Electrolytes via UiO-66 Fibrous Membranes with Different Functional Groups for Solid-State Sodium Metal Batteries. ACS Applied Energy Materials, [PMID:] [10.1021/acsaem.6c00256] |
| 47. Jing Li, Jinquan Wan, Yan Wang. (2026) Electronic effect-guided ligand functionalization of MIL-101 (Fe): Unlocking a new perspective for regulating ROS generation in Fenton-like systems. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2026.137446] |