NMDA - Moligand™, 100mmol/L dans H2O , CAS No.6384-92-5

CAS: 6384-92-5 Cat. No.: N276566 Formule: C₅H₉NO₄ Poids moléculaire: 147.13 Beilstein Registry Number: 1724431

QUALITÉ & PURETÉ Moligand™, 100mmol/L in H2O

Synonyms

(R)-2-(Methylamino)succinic acid hydrochloride|(2R)-2-(methylamino)butanedioic acid|(R)-2-Ethylbutannedioic acid|(R)-2-(Methylamino)succinicacid|METHYL ASPARTIC ACID, D-|Me-D-Asp-OH|N-Me-D-Asp-OH|NMDA (N-Methyl-D-aspartic acid)|N-Methyl aspartic acid|(R)-2-Methylamino-succinic acid|N-Methyl-Daspartate|N-Methyl-D-aspartate|SDCCGSBI-0050753.P003|Lopac-M-3262|N-Methylaspartate|N-methyl-D-aspartic acid|2-Methylamino-succinic acid|NMDA|N-methyl D-aspartate|N-methyl D-aspartic acid|Aspartic acid, N-methyl-|OEM|methyl-d-aspartic acid|Methyl aspartic acid|(NMDA)|D-Aspartic acid, N-methyl-|n-methyl-d-aspartic acid (nmda)|N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5

Storage

A conserver à 2-8°C,Dessiccation

Shipped In

Glace humide

Vue d’ensemble

Conserver à +4°C. Stocker dans des conditions de dessiccation. Le produit peut être conservé jusqu'à 12 mois.

Spécifications

Synonymes

(R)-2-(Methylamino)succinic acid hydrochloride | (2R)-2-(methylamino)butanedioic acid | (R)-2-Ethylbutannedioic acid | (R)-2-(Methylamino)succinicacid | METHYL ASPARTIC ACID, D- | Me-D-Asp-OH | N-Me-D-Asp-OH | NMDA (N-Methyl-D-aspartic acid) | N-Methyl aspartic acid | (R)-2-Methylamino-succinic acid | N-Methyl-Daspartate | N-Methyl-D-aspa Afficher plus

Spécifications et pureté

Moligand™, 100mmol/L dans H2O

Mécanismes biochimiques et physiologiques

Acide aminé excitotoxique. Agoniste prototypique du récepteur ionotropique NMDA du glutamate, impliqué dans la potentialisation à long terme, l'ischémie et l'épilepsie. Soluble dans 1 ml d'eau pour obtenir une concentration spécifiée de mM/ml. Pour en sav

Conditions de stockage de stockage

A conserver à 2-8°C,Dessiccation

Expédié en

Glace humide

Grade

Moligand™

Note

Dans la mesure du possible, les solutions doivent être préparées et utilisées le même jour. Toutefois, si vous devez préparer des solutions de base à l'avance, nous vous recommandons de les conserver sous forme d'aliquotes dans des flacons hermétiques à -20°C. Ces aliquotes sont généralement utilisables pendant un mois. En général, ces solutions peuvent être utilisées pendant un mois. Avant utilisation, et avant d'ouvrir le flacon, nous vous recommandons de laisser votre produit s'équilibrer à température ambiante pendant au moins 1 heure. Besoin de plus de conseils sur la solubilité, l'utilisation et la manipulation ? Veuillez consulter notre page de questions fréquemment posées (FAQ) pour plus de détails.

Noms et identifiants

Pubchem Sid

528766291

Sourires canoniques

CNC(CC(=O)O)C(=O)O

IUPAC Name

(2R)-2-(methylamino)butanedioic acid

InChIKey

HOKKHZGPKSLGJE-GSVOUGTGSA-N

INCHI

1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1

Isomères SMILES

CN[C@H](CC(=O)O)C(=O)O

RTECS

CI9457000

Poids moléculaire

147.13

Beilstein

1724431

Reaxy-Rn

1724430

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1724430&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Aspartic acid and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Aspartic acid and derivatives
• Alternative Parents: D-alpha-amino acids Fatty acids and conjugates Dicarboxylic acids and derivatives Amino acids Dialkylamines Carboxylic acids Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Aspartic acid or derivatives - Alpha-amino acid - D-alpha-amino acid - Dicarboxylic acid or derivatives - Fatty acid - Amino acid - Carboxylic acid - Secondary aliphatic amine - Secondary amine - Amine - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as aspartic acid and derivatives. These are compounds containing an aspartic acid or a derivative thereof resulting from reaction of aspartic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: secondary amino compound - amino dicarboxylic acid - D-alpha-amino acid - D-aspartic acid derivative

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in 1ml of water to give specified mM/ml concentration
• Rotation spécifique [α]: -15° (C=2,H2O)
• Point de fusion (°C): 178 °C
• Poids moléculaire: 147.130 g/mol
• XLogP3: -3.400
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 147.053 Da
• Monoisotopic Mass: 147.053 Da
• Topological Polar Surface Area: 86.600 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 145.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1