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OSMI-4 - 10mM in DMSO , CAS No.2260791-14-6

CAS: 2260791-14-6 Cat. No.: O422714 Formule: C27H26ClN3O7S2 Poids moléculaire: 604.09 PubChem CID: 137319721
COA
OSMI-4 - 10mM in DMSO CAS No(2260791-14-6) by Aladdin Scientific
DISPONIBLE À COMMANDE
GRADE & PURITY 10mM in DMSO
Synonyms
ethyl (R)-N-(2-((7-chloro-2-oxo-1,2-dihydroquinoline)-6-sulfonamido)-2-(2-methoxyphenyl)acetyl)-N-(thiophen-2-ylmethyl)glycinate
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
USA
Allemagne (EU)*
Price
Qty
1ml
O422714-1ml
3 En stock
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205,90$US

241,90$US
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Vue d’ensemble Specifications Propriétés du produit Noms et identifiants Documentation Advanced Data Structure 3D Certificats (CoA, COO, BSE/TSE et tableau d'analyse) Propriétés chimiques et physiques Calculateurs de solution Avis
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

Information

OSMI-4 OSMI-4 is an inhibitor of O-GlcNAc transferase (OGT) with EC50 of 3 μM in cells.

Targets

OGT (Cell-free assay) 3 μM(EC50)

In vitro

OSMI-4 reduces O-GlcNAc levels almost completely by 5 μM. A decrease in HCF-1 cleavage products and the appearance of uncleaved HCF-1 is observed in cells treated with OSMI-4. OSMI-4 is a kind of structure-based evolution of small molecule OGT inhibitors with low nanomolar binding affinities. OSMI-4 exhibits a ~3 μM EC50 in cells, making it especially attractive for probing OGT’s complex biology.

Cell Research(from reference)

Cell lines：HEK293T cells 

Concentrations：5 μM, 10 μM, 20 μM 

Incubation Time：2 h, 8 h, 16 h, 24 h 

Specifications

Synonymes
ethyl (R)-N-(2-((7-chloro-2-oxo-1,2-dihydroquinoline)-6-sulfonamido)-2-(2-methoxyphenyl)acetyl)-N-(thiophen-2-ylmethyl)glycinate
Spécifications et pureté
10mM in DMSO
Mécanismes biochimiques et physiologiques
OSMI-4 is an inhibitor of O-linked N-acetylglucosamine transferase (O-GlcNAc transferase, OGT) with EC50 of 3 μM in cells.
Conditions de stockage de stockage
Store at -80°C
Expédié en
Dry ice packs + Cold packs
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
INHIBITOR
Propriétés du produit
ALogP3.175
Nombre de HBD2
Liaison rotative12
Noms et identifiants
Pubchem Sid528766484
Sourires canoniquesCCOC(=O)CN(CC1=CC=CS1)C(=O)C(C2=CC=CC=C2OC)NS(=O)(=O)C3=C(C=C4C(=C3)C=CC(=O)N4)Cl
IUPAC Nameethyl 2-[[(2R)-2-[(7-chloro-2-oxo-1H-quinolin-6-yl)sulfonylamino]-2-(2-methoxyphenyl)acetyl]-(thiophen-2-ylmethyl)amino]acetate
InChIKeySTPSLAZMEWZDAJ-AREMUKBSSA-N
INCHI1S/C27H26ClN3O7S2/c1-3-38-25(33)16-31(15-18-7-6-12-39-18)27(34)26(19-8-4-5-9-22(19)37-2)30-40(35,36)23-13-17-10-11-24(32)29-21(17)14-20(23)28/h4-14,26,30H,3,15-16H2,1-2H3,(H,29,32)/t26-/m1/s1
PubChem CID 137319721
Poids moléculaire 604.09

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Structure 3D
Modèle de structure chimique interactif





Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateArticle
J2415602Certificate of AnalysisAug 01, 2026 O422714
Propriétés chimiques et physiques
DMSO (mg/mL) Solubilité maximale100
DMSO (mM) Solubilité maximale165.538247612111
Eau (mg/mL) Solubilité maximale＜1
Calculateurs de solution
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