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Moligand™, ≥96% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
PD 168368 is a Neuromedin B antagonist displaying ~40-fold selectivity over the gastrin-releasing peptide receptor (GRP-R, BB2). PD 168368 also shows >300-fold selectivity over BRS-R (BB3). PD 168368 antagonizes neuromedin B-stimulated Ca|2+|release. Simultaneously, PD 168368 inhibits proliferation of rat glioma cells.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Classe | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives |
| Direct Parent | N-carbamoyl-alpha amino acids and derivatives |
| Alternative Parents | Tryptamines and derivatives Alpha amino acid amides 3-alkylindoles N-phenylureas Nitrobenzenes Nitroaromatic compounds Substituted pyrroles Pyridines and derivatives Fatty amides Heteroaromatic compounds Ureas Secondary carboxylic acid amides Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Organic oxoazanium compounds Organic zwitterions Organonitrogen compounds Carbonyl compounds Hydrocarbon derivatives Organopnictogen compounds Organic oxides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | N-carbamoyl-alpha-amino acid or derivatives - Alpha-amino acid amide - Triptan - N-phenylurea - 3-alkylindole - Indole - Indole or derivatives - Nitrobenzene - Nitroaromatic compound - Monocyclic benzene moiety - Fatty amide - Pyridine - Substituted pyrrole - Benzenoid - Fatty acyl - Heteroaromatic compound - Pyrrole - Carboxamide group - C-nitro compound - Carbonic acid derivative - Organic nitro compound - Secondary carboxylic acid amide - Urea - Organic oxoazanium - Organic 1,3-dipolar compound - Organoheterocyclic compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Azacycle - Organooxygen compound - Organonitrogen compound - Organic zwitterion - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as n-carbamoyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an carbamoyl group at its terminal nitrogen atom. |
| External Descriptors | Not available |
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| Solubilité | Soluble in DMSO (100 mM). |
|---|---|
| Indice de réfraction | n20D1.66 (Predicted) |
| Point d'ébullition (°C) | ~819.7° C at 760 mmHg (Predicted) |
| Poids moléculaire | 554.600 g/mol |
| XLogP3 | 5.200 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 8 |
| Exact Mass | 554.264 Da |
| Monoisotopic Mass | 554.264 Da |
| Topological Polar Surface Area | 145.000 Ų |
| Heavy Atom Count | 41 |
| Formal Charge | 0 |
| Complexity | 913.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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