Pomalidomide-PEG2-COOH - ≥95%(HPLC) , CAS No.2140807-17-4

CAS: 2140807-17-4 Cat. No.: P288308 Formule: C₂₀H₂₃N₃O₈ Poids moléculaire: 433.42 PubChem CID: 134589759

GRADE & PURITY ≥95%(HPLC)

Synonyms

3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic acid | Pomalidomide-PEG2-CO2H | 3-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)propanoic acid | CrosslinkerE3 Li

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

PROTAC

Specifications

Synonymes

3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic acid | Pomalidomide-PEG2-CO2H | 3-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)propanoic acid | CrosslinkerE3 Li

Spécifications et pureté

≥95%(HPLC)

Mécanismes biochimiques et physiologiques

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal acid ready for conjugation to a target protein ligand.

Conditions de stockage de stockage

Store at -20°C,Argon charged

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥95%(HPLC)

Noms et identifiants

• Pubchem Sid: 504773171
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773171
• Sourires canoniques: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCC(=O)O
• IUPAC Name: 3-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]propanoic acid
• InChIKey: NKISJPXMSOQWER-UHFFFAOYSA-N
• INCHI: 1S/C20H23N3O8/c24-15-5-4-14(18(27)22-15)23-19(28)12-2-1-3-13(17(12)20(23)29)21-7-9-31-11-10-30-8-6-16(25)26/h1-3,14,21H,4-11H2,(H,25,26)(H,22,24,27)
• PubChem CID: 134589759
• Poids moléculaire: 433.42

Propriétés chimiques et physiques

• Sensibilité: Moisture sensitive
• Poids moléculaire: 433.400 g/mol
• XLogP3: 0.100
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 11
• Exact Mass: 433.149 Da
• Monoisotopic Mass: 433.149 Da
• Topological Polar Surface Area: 151.000 Ų
• Heavy Atom Count: 31
• Formal Charge: 0
• Complexity: 727.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1