Pyocyanin - Moligand™, ≥98% , CAS No.85-66-5

CAS: 85-66-5 Cat. No.: P275084 Formule: C₁₃H₁₀N₂O Poids moléculaire: 210.23 Numéro CE: 687-347-7 PubChem CID: 6817

GRADE & PURITY Moligand™, ≥98%

Synonyms

5-methylphenazin-1-one | 5-methylphenazin-1(5H)-one | 5-methyl-1,5-dihydrophenazin-1-one | Pyocyanin | PYOCYANINE | Pyrocyanine | 5-methylphenazin-5-ium-1-olate | Pyocyanin; Pyrocyanine; Sanasin; Sanazin | Sanasin

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

Synonymes

5-methylphenazin-1-one | 5-methylphenazin-1(5H)-one | 5-methyl-1,5-dihydrophenazin-1-one | Pyocyanin | PYOCYANINE | Pyrocyanine | 5-methylphenazin-5-ium-1-olate | Pyocyanin; Pyrocyanine; Sanasin; Sanazin | Sanasin

Spécifications et pureté

Moligand™, ≥98%

Mécanismes biochimiques et physiologiques

Catalase inhibitor. Aryl hydrocarbon receptor activator (K i = 5.4 µM). Reduces gene expression of catalase. Promotes extracellular DNA release. Generates ROS. Induces apoptosis in neutrophils in vivo.

Conditions de stockage de stockage

Protected from light,Store at -20°C,Desiccated

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

INHIBITOR

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureté

≥98%

Noms et identifiants

Pubchem Sid

528774625

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528774625

Sourires canoniques

CN1C2=CC=CC=C2N=C3C1=CC=CC3=O

IUPAC Name

5-methylphenazin-1-one

InChIKey

YNCMLFHHXWETLD-UHFFFAOYSA-N

INCHI

1S/C13H10N2O/c1-15-10-6-3-2-5-9(10)14-13-11(15)7-4-8-12(13)16/h2-8H,1H3

Isomères SMILES

CN1C2=CC=CC=C2N=C3C1=CC=CC3=O

WGK Allemagne

1

PubChem CID

6817

Poids moléculaire

210.23

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Diazanaphthalenes
      • Subclass Benzodiazines
        • Level5 Quinoxalines
          • Level6 Phenazines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Quinoxalines
• Direct Parent: Phenazines and derivatives
• Alternative Parents: Pyrazines Benzenoids Vinylogous amides Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Phenazine - Benzenoid - Pyrazine - Heteroaromatic compound - Vinylogous amide - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as phenazines and derivatives. These are polycyclic aromatic compounds containing a phenazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a pyrazine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Clear blue solution at 5mg/ml of Ethanol; Clear blue solution at 5mg/ml of DMSO
• Sensibilité: Light sensitive; Moisture sensitive
• Poids moléculaire: 210.230 g/mol
• XLogP3: 2.000
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 210.079 Da
• Monoisotopic Mass: 210.079 Da
• Topological Polar Surface Area: 32.700 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 420.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1