QUALITÉ & PURETÉAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.Fc tag?Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture.≥95%(SDS-PAGE)
Accession #
Q08722
Protein Tag
C-hFc
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
1. Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC50 of human CD47 Protein is 50.0 - 200.0 ng/mL. 2. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD47 Protein (rp144028) at 1 μg/mL can bind Magrolimab (anti-CD47) (Ab169323) with the EC50 of 10.34 ng/mL.
Animal Free,Carrier Free,Bioactive,ActiBioPure™,Azide Free,Fc tag,≥95%(SDS-PAGE) ActiBioPure™,Animal Free,Azide Free,Bioactive,Carrier Free,Fc tag pour les flux de travail chromatographiques et analytiques sensibles nécessitant une interférence de ligne de base minimale.
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Stockage & expédition
Store at -20°C,Avoid repeated freezing and thawing Expédition Ice chest + Ice pads. Consultez le COA spécifique au lot pour les spécifications exactes.
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Documents qualité
SDS, COA, fiche technique et fiche de spécifications disponibles au téléchargement. COA spécifique au lot accessible via la recherche par numéro de lot.
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Preuve documentaire
Cité dans 0 publications à comité de lecture couvrant la chromatographie, la synthèse organique et les réactions de couplage croisé.
Vue d’ensemble
Purity >95% (SDS-PAGE) Endotoxin level <1.0 EU/μg Function Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Spécifications
Product Name
Recombinant Human CD47 Protein, >95% (SDS-PAGE)
Synonymes
antigen identified by monoclonal 1D8 | Antigenic surface determinant protein OA3 | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | CD47 antigen | CD47 glycoprotein | CD47 molecule | CD47 | IAP | IAPintegrin associated protein |
Grade
ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, Fc tag
1. Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC50 of human CD47 Protein is 50.0 - 200.0 ng/mL. 2. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD47 Protein (rp144028) at 1 μg/mL can bind Magrolimab (anti-CD47) (Ab169323) with the EC50 of 10.34 ng/mL.
59.3 kDa, under reducing conditions; 109.3 kDa, under non-reducing conditions.
Type de molécule
Protein
Product Line
Produits biologiques
Stockage et expédition
Forme
Lyophilized
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25mg/mL.
Conditions de stockage de stockage
Store at -20°C,Avoid repeated freezing and thawing
Expédié en
Ice chest + Ice pads
Stabilité et stockage
Samples are stable for twelve months from date of receipt at -20℃ to -80℃. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant Human CD47 Protein (rp144028) - Protein Bioactivity Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC₅₀ of human CD47 Protein is 50.0 - 200.0 ng/mL.
Recombinant Human CD47 Protein (rp144028) - ELISA Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD47 Protein (rp144028) at 1 μg/mL can bind Magrolimab (anti-CD47) (Ab169323) with the EC₅₀ of 10.34 ng/mL.
Recombinant Human CD47 Protein (rp144028) - SDS-PAGE 3 μg/lane of Recombinant Human CD47 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 59.3 kDa under reducing conditions and 109.3 kDa under non-reducing conditions.
Recombinant Human CD47 Protein (rp144028) - Binding Activity Immobilized Recombinant Human SIRP alpha/CD172a Protein (rp183642) at 1.0 μg/mL can bind Recombinant Human CD47 Protein (rp144028) with the EC₅₀ of 829.1 ng/mL.
Documentation
📋 Fiche de données de sécurité (FDS)
Document complet couvrant les dangers, la manipulation, le stockage et la conformité réglementaire.
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
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Reconstitution Calculator
Avis
Avis des clients
Foire aux questions
What is the purity of this product, and how is it determined?
This product is supplied at ≥95% purity, determined by SDS-PAGE. Lot-specific values are stated on the Certificate of Analysis.
What does Animal Free mean?
Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.
What does Carrier Free mean?
Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.
How should this product be stored?
Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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