SC99 - ≥98% , CAS No.882290-02-0

CAS: 882290-02-0 Cat. No.: S412698 Formule: C₁₅H₈Cl₂FN₃O Poids moléculaire: 336.15 PubChem CID: 5896323

QUALITÉ & PURETÉ ≥98%

Synonyms

N'-(3-Chloro-4-fluorophenyl)-2-(4-chlorophenyl)-2-oxoacetohydrazonoyl cyanide

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Information

SC99 is an orally active, selective inhibitor of STAT3 that docks into the ATP-binding pocket of JAK2 and inhibits phosphorylation of JAK2 and STAT3. SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activities.

Spécifications

Synonymes

N'-(3-Chloro-4-fluorophenyl)-2-(4-chlorophenyl)-2-oxoacetohydrazonoyl cyanide

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

SC99 is an orally active, selective inhibitor of STAT3 that docks into the ATP-binding pocket of JAK2 and inhibits phosphorylation of JAK2 and STAT3. SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti

Conditions de stockage de stockage

Protected from light,Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

ACTIVATOR

Pureté

≥98%

Noms et identifiants

Pubchem Sid

528767066

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528767066

Sourires canoniques

C1=CC(=CC=C1C(=O)C(=NNC2=CC(=C(C=C2)F)Cl)C#N)Cl

IUPAC Name

(1E)-N-(3-chloro-4-fluoroanilino)-2-(4-chlorophenyl)-2-oxoethanimidoyl cyanide

InChIKey

ZKULFSMYRSFHKE-KGENOOAVSA-N

INCHI

1S/C15H8Cl2FN3O/c16-10-3-1-9(2-4-10)15(22)14(8-19)21-20-11-5-6-13(18)12(17)7-11/h1-7,20H/b21-14+

Isomères SMILES

C1=CC(=CC=C1C(=O)/C(=N/NC2=CC(=C(C=C2)F)Cl)/C#N)Cl

PubChem CID

5896323

Poids moléculaire

336.15

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Phenylhydrazines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Phenylhydrazines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylhydrazines
• Alternative Parents: Benzoyl derivatives Aryl ketones Fluorobenzenes Chlorobenzenes Aryl fluorides Aryl chlorides Nitriles Hydrazones Organopnictogen compounds Organofluorides Organochlorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzoyl - Phenylhydrazine - Aryl ketone - Chlorobenzene - Fluorobenzene - Halobenzene - Aryl halide - Aryl chloride - Aryl fluoride - Ketone - Hydrazone - Carbonitrile - Nitrile - Organic oxide - Organohalogen compound - Organochloride - Organofluoride - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent attached to a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (non humaines)

Plasmodium berghei (192651 Activities)

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Mécanismes d'action

Propriétés chimiques et physiques

• Sensibilité: Light sensitive