Sumatriptan - Moligand™, 10 mM in DMSO , CAS No.103628-46-2

CAS: 103628-46-2 Cat. No.: S1499318 Molecular Weight: 295.4 Beilstein Registry Number: 6930870 EC Number: 600-462-9 PubChem CID: 5358

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC 50 s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT 1D , 5-HT 1B and 5-HT 1F receptors, respectively. Sumatriptan can be used for migraine headache research .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Product Properties

• pKa: pKₐ: 11.31 (Predicted), pKₐ: 9.49 (Predicted)
• Ki Data: SR-1B: Ki= 5.5 nM (human); SR-2a: Ki= 7.3 nM (human); D2DR: Ki>218 nM (human); SR-1A: Ki= 230 nM (human); SR-1D: Ki= 376 nM (human)
• ALogP: 0.9

Names and Identifiers

• Isomeric SMILES: CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C
• PubChem CID: 5358
• Molecular Weight: 295.4
• Beilstein: 6930870

Chemical and Physical Properties

• Refractive Index: n20D1.61 (Predicted)
• Boil Point(°C): 497.7° C at 760 mmHg (Predicted)
• Melt Point(°C): 169-171° C