Tabalumab (anti-BAFF) - Primary antibody, specific to TNFSF13B, >95%, Human IgG4SP, INHIBITOR of Tumor necrosis factor ligand superfamily member 13B inhibitor, INHIBITOR of Tumor necrosis factor ligand superfamily member 13B inhibitor

CAS: 1143503-67-6 Cat. No.: Ab175663

GRADE & PURITY Animal Free, Carrier Free, Recombinant, Validated, ExactAb™, Low Endotoxin, Azide Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Human

Reactive species

Human, Mouse

Isotype

Human IgG4SP

Conjugation

Unconjugated

Vue d’ensemble

Tabalumab (anti-BAFF) is a humanised anti-BAFF (B-cell activating factor) monoclonal antibody (IgG4 type) with neutralising activity against membrane bound and soluble BAFF. Tabalumab (anti-BAFF) can be used in studies of autoimmune diseases such as rheumatoid arthritis, renal failure and systemic lupus erythematosus.

Specifications

Product Name

Tabalumab (anti-BAFF) - Primary antibody, specific to TNFSF13B, >95%, Human IgG4SP, INHIBITOR of Tumor necrosis factor ligand superfamily member 13B inhibitor

Synonymes

ApoL related ligand TALL 1 antibody | B cell Activating Factor antibody | B lymphocyte stimulator antibody | B-cell-activating factor antibody | BAFF antibody | BLyS antibody | CD 257 antibody | CD257 antibody | CD257 antigen antibody | Delta BAFF antibod

Spécifications et pureté

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Espèce hôte

Human

Spécificité

TNFSF13B

Conjugation

Unconjugated

Grade

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Type d'action

INHIBITOR

Mécanisme d'action

INHIBITOR of Tumor necrosis factor ligand superfamily member 13B inhibitor

Isotype

Human IgG4SP

Type de chaîne lumineuse

kappa

SDS-PAGE

27.6 kDa (Light Chain) & 51.0 kDa (Heavy Chain), under reducing conditions; 177.2 kDa, under non-reducing conditions.

Méthode de purification

Protein A purified

La pureté

>95%

Concentration

See COA

CAS

1143503-67-6

Stockage et expédition

Forme

Liquid

Conditions de stockage de stockage

Store at -80°C,Avoid repeated freezing and thawing

Expédié en

Dry ice packs + Cold packs

Stabilité et stockage

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Images

SEC: Tabalumab (anti-BAFF) (Ab175663)

Tabalumab (anti-BAFF) (Ab175663) - SEC
The purity of Tabalumab (anti-BAFF) (Ab175663) is more than 95% verified by HPLC.

Cibles associées (humaines)

TNFSF13B Tclin Tumor necrosis factor ligand superfamily member 13B (0 Activities)

Discover Target: TNFSF13B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mécanismes d'action

Foire aux questions

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1143503-67-6.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Tabalumab (anti-BAFF)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.