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TYK2

DescriptionNon-receptor tyrosine-protein kinase TYK2

Gene and Protein Information

Gene ID7297
Uniprot Accession IDs P29597 Q6QB10 Q96CH0
Ensembl ID ENSP00000431885
Symbole JTK1 IMD35
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
Sequence
MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomNuméro d'identification fiscale Other Gene IDSources
Chimp455703TYK2tyrosine kinase 29598VGNC:2210OMA, EggNOG
Macaque574130TYK2tyrosine kinase 29544OMA, EggNOG
Mouse54721Tyk2tyrosine kinase 210090MGI:1929470Inparanoid, OMA, EggNOG
Rat100361294Tyk2tyrosine kinase 210116RGD:2320469Inparanoid, OMA, EggNOG
Dog476714TYK2tyrosine kinase 29615VGNC:48024Inparanoid, OMA, EggNOG
HorseTYK2tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440]9796OMA, EggNOG
Cow512484TYK2tyrosine kinase 29913VGNC:36548Inparanoid, OMA, EggNOG
Pig397363TYK2tyrosine kinase 29823Inparanoid, OMA, EggNOG
Opossum100012931TYK2tyrosine kinase 213616Inparanoid, OMA, EggNOG
Anole lizard100566727tyk2tyrosine kinase 228377Inparanoid, OMA
Xenopus100489432tyk2tyrosine kinase 28364XB-GENE-993652Inparanoid, OMA
Zebrafish100536675tyk2tyrosine kinase 27955ZDB-GENE-071116-4Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    JAKA family    /    Non-receptor tyrosine-protein kinase tyk2

Associated Recombinant Proteins

NomSpecification and purityExpression systemProtein labelDisponibilitéVoir les détails

Associated Antibodies

NomSpecificationsSpecies reactivityApplicationDisponibilitéVoir les détails

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomDirect Associated TargetsDisease TypeMondoid

      Bibliography

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