(±)-trans-ACPD - ≥99%(HPLC) , CAS No.67684-64-4

CAS: 67684-64-4 Cat. No.: T288890 Formule: C₇H₁₁NO₄ Poids moléculaire: 173.17

QUALITÉ & PURETÉ ≥99%(HPLC)

Synonyms

(1R,3S)-ACPD | Trans-( inverted exclamation markA)-ACP | 1-Amino-cyclopentane-1,3-dicarboxylic acid(trans-ACPD) | t-ACPD | SCHEMBL4835874 | 1-Amino-1,3-cyclopentanedicarboxylic acid | AJ-190/40848563 | BDBM50060136 | 1-Amino-1,3-dicarboxycyclopentane | BC

Storage

Room temperature

Shipped In

Normal

Spécifications

Synonymes

(1R,3S)-ACPD | Trans-( inverted exclamation markA)-ACP | 1-Amino-cyclopentane-1,3-dicarboxylic acid(trans-ACPD) | t-ACPD | SCHEMBL4835874 | 1-Amino-1,3-cyclopentanedicarboxylic acid | AJ-190/40848563 | BDBM50060136 | 1-Amino-1,3-dicarboxycyclopentane | BC

Spécifications et pureté

≥99%(HPLC)

Mécanismes biochimiques et physiologiques

Equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD. Selective agonist for metabotropic glutamate receptors; active at both group I and group II mGlu receptors (EC50values are 2, 15, 23 and ~800μM at mGluR2, mGluR1, mGluR5and mGluR4respectively).(1S,3R)-AC

Conditions de stockage de stockage

Room temperature

Expédié en

Normal

Type d'action

AGONIST

Pureté

≥99%(HPLC)

Noms et identifiants

Sourires canoniques

C1CC(CC1C(=O)O)(C(=O)O)N

IUPAC Name

(1R,3S)-1-aminocyclopentane-1,3-dicarboxylic acid

InChIKey

YFYNOWXBIBKGHB-MHTLYPKNSA-N

INCHI

1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7+/m0/s1

Isomères SMILES

C1C[C@@](C[C@H]1C(=O)O)(C(=O)O)N

Poids moléculaire

173.17

Reaxy-Rn

3031649

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3031649&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: D-alpha-amino acids Dicarboxylic acids and derivatives Amino acids Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: D-alpha-amino acid - L-alpha-amino acid - Dicarboxylic acid or derivatives - Amino acid - Carboxylic acid - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic nitrogen compound - Carbonyl group - Amine - Organic oxide - Aliphatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

GRM4 Tchem Metabotropic glutamate receptor 4 (2320 Activities)

Discover Target: GRM4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRM1 Tchem Metabotropic glutamate receptor 1 (2309 Activities)

Discover Target: GRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cibles associées (non humaines)

Grm2 Metabotropic glutamate receptor 2 (1326 Activities)

Discover Target: Grm2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc17a8 Vesicular glutamate transporter 3 (89 Activities)

Discover Target: Slc17a8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Solvent:water, Max Conc. mg/mL: None, Max Conc. mM: 5 with gentle warming; Solvent:1eq. NaOH, Max Conc. mg/mL: 8.66, Max Conc. mM: 50
• Poids moléculaire: 173.170 g/mol
• XLogP3: -3.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 173.069 Da
• Monoisotopic Mass: 173.069 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 227.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1