Trimethoprim - Moligand™, 10mM in DMSO , CAS No.738-70-5

CAS: 738-70-5 Cat. No.: T408410 Formule: C₁₄H₁₈N₄O₃ Poids moléculaire: 290.32 Beilstein Registry Number: 25(5)13,429 Numéro CE: 212-006-2 PubChem CID: 5578

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

BW 56-72, NIH 204, NSC-106568 | 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Information

Trimethoprim Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
In vitro

Trimethoprim acts by interfering with the action of bacterial dihydrofolate reductase, inhibiting synthesis of tetrahydrofolic acid. The Inhibition starves the bacteria of nucleotides necessary for DNA replication causing, in certain circumstances, cell lethality due to thymineless death.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonymes

BW 56-72, NIH 204, NSC-106568 | 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine

Spécifications et pureté

Moligand™, 10mM in DMSO

Mécanismes biochimiques et physiologiques

Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Propriétés du produit

• ALogP: 0.9

Noms et identifiants

• Isomères SMILES: COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
• RTECS: UV8225000
• PubChem CID: 5578
• Numéro ONU: 2811
• Groupe d'emballage: I
• Poids moléculaire: 290.32
• Beilstein: 25(5)13,429
• Reaxy-Rn: 625127

Cibles associées (humaines)

DHFR Tclin Dihydrofolate reductase (0 Activities)

Discover Target: DHFR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propriétés chimiques et physiques

• Point de fusion (°C): 199-203℃