Determine the necessary mass, volume, or concentration for preparing a solution.
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≥900u/mg for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 24 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Biological activity:
Tylosin is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle
| Canonical Smiles | CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC |
|---|---|
| IUPAC Name | 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde |
| InChIKey | WBPYTXDJUQJLPQ-VMXQISHHSA-N |
| INCHI | 1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-/m1/s1 |
| Isomeric SMILES | CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC |
| PubChem CID | 5280440 |
| Molecular Weight | 916.12 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Class | Organooxygen compounds |
| Subclass | Carbohydrates and carbohydrate conjugates |
| Intermediate Tree Nodes | Aminosaccharides |
| Direct Parent | Aminoglycosides |
| Alternative Parents | Macrolides and analogues Disaccharides O-glycosyl compounds Oxanes Alpha-hydrogen aldehydes Tertiary alcohols 1,2-aminoalcohols Trialkylamines Amino acids and derivatives Carboxylic acid esters Cyclic ketones Secondary alcohols Lactones Acetals Dialkyl ethers Oxacyclic compounds Monocarboxylic acids and derivatives Hydrocarbon derivatives Organopnictogen compounds Organic oxides |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Aminoglycoside core - Macrolide - Disaccharide - Glycosyl compound - O-glycosyl compound - Oxane - Alpha-hydrogen aldehyde - Tertiary alcohol - 1,2-aminoalcohol - Amino acid or derivatives - Carboxylic acid ester - Ketone - Lactone - Cyclic ketone - Secondary alcohol - Tertiary aliphatic amine - Tertiary amine - Acetal - Organoheterocyclic compound - Ether - Monocarboxylic acid or derivatives - Dialkyl ether - Oxacycle - Carboxylic acid derivative - Organopnictogen compound - Carbonyl group - Alcohol - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Organic nitrogen compound - Amine - Aldehyde - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars. |
| External Descriptors | Macrolides and lactone polyketides |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Sep 04, 2025 | T302817 | |
| Certificate of Analysis | Sep 04, 2025 | T302817 | |
| Certificate of Analysis | Sep 04, 2025 | T302817 | |
| Certificate of Analysis | Sep 04, 2025 | T302817 |
| Molecular Weight | 916.100 g/mol |
|---|---|
| XLogP3 | 1.000 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 18 |
| Rotatable Bond Count | 13 |
| Exact Mass | 915.519 Da |
| Monoisotopic Mass | 915.519 Da |
| Topological Polar Surface Area | 239.000 Ų |
| Heavy Atom Count | 64 |
| Formal Charge | 0 |
| Complexity | 1560.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 21 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 2 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 2 |
| Covalently-Bonded Unit Count | 1 |
| 1. Linsen Ruan, Kaiyu Ye, Zhicheng Wang, Anqi Xiong, Rong Qiao, Jibin Zhang, Zhiyong Huang, Minmin Cai, Chan Yu. (2023) Characteristics of gut bacterial microbiota of black soldier fly (Diptera: Stratiomyidae) larvae effected by typical antibiotics. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, [PMID:38154153] [10.1016/j.ecoenv.2023.115861] |
| 2. Song Lianjun, Wang Youyi, Li Qingyue, Wang Jinkui, Gao Tian, An Zhaohuan, Liu Qinfang, Mao Yexuan, Bu Tong, Huang Xianqing, Ma Yan, Wang Zhanhui, Zhang Xiya. (2023) Production of monoclonal antibody against tylosin and tilmicosin with homogeneous cross-reactivity and its application in lateral flow immunoassay. MICROCHIMICA ACTA, 191 (1): (1-12). [PMID:38114730] [10.1007/s00604-023-06132-z] |
| 3. Xin-Yu Liu, Xiao-Yun Gu, Chen Liu, Lanre Anthony Gbadegesin, Yang He, Jian-Qiang Zhang. (2023) Field migration of veterinary antibiotics via surface runoff from chicken-raising orchard in responding to natural rainfalls. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:37967624] [10.1016/j.scitotenv.2023.168527] |
| 4. Wenjing Li, Yang Li, Junlong Cai, Yue Wang, Yanan Liu, Hankun Hu, Liang Liu. (2023) Simultaneous Quantification of Seven Antifungal Agents in Human Serum Using Liquid Chromatography-Tandem Mass Spectrometry. Pharmaceuticals, 16 (11): (1537). [PMID:38004403] [10.3390/ph16111537] |
| 5. Xiangdong Zhang, Jian Zhang, Bowen Hou, Xueying Yang, Junlian Ren, Chen Shao. (2023) Efficient removal of oxytetracycline hydrochloride by ZIF-67 coated hollow spherical CuS (CuS-PVP@ZIF-67) under the synergistic effect of adsorption and PMS activation. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2023.158663] |
| 6. Yu Wang, Jin-Yi Yang, Ying He, Lu Li, Jian-Xin Huang, Yuan-Xin Tian, Hong Wang, Zhen-Lin Xu, Yu-Dong Shen. (2021) Development of Time-Resolved Fluorescence Immunochromatographic Assays for Simultaneously Detecting Tylosin and Tilmicosin in Milk in Group-Screening Manner. Foods, 10 (8): (1838). [PMID:34441616] [10.3390/foods10081838] |
| 7. Zaiming Chen, Jianfei Wang, Yuefeng Wang, Bing Li, Meizhen Wang. (2021) Rapid formation of pyrogenic char (biochar) with high and low sorption capacity towards organic chemicals. ENVIRONMENTAL POLLUTION, [PMID:33460877] [10.1016/j.envpol.2021.116472] |
| 8. Yanmei Sun, Yajie Guo, Mingming Shi, Tianlei Qiu, Min Gao, Shulei Tian, Xuming Wang. (2020) Effect of antibiotic type and vegetable species on antibiotic accumulation in soil-vegetable system, soil microbiota, and resistance genes. CHEMOSPHERE, [PMID:33297095] [10.1016/j.chemosphere.2020.128099] |
| 9. Guanqiong Na, Xiaofei Hu, Yaning Sun, Sharon Kwee, Guangxu Xing, Yunrui Xing, Gaiping Zhang. (2020) A highly sensitive monoclonal antibody−based paper sensor for simultaneously detecting valnemulin and tiamulin in porcine liver. JOURNAL OF FOOD SCIENCE, 85 (6): (1681-1688). [PMID:32418205] [10.1111/1750-3841.15136] |
| 10. Shanshan Wang, Nana Xue, Wenfeng Li, Daoyong Zhang, Xiangliang Pan, Yongming Luo. (2019) Selectively enrichment of antibiotics and ARGs by microplastics in river, estuary and marine waters. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:31796269] [10.1016/j.scitotenv.2019.134594] |
| 11. Chan-Yuan YAO, Jin-Yi YANG, Zhen-Lin XU, Hong WANG, Hong-Tao LEI, Yuan-Ming SUN, Yuan-Xin TIAN, Yu-Dong SHEN. (2018) Indirect Competitive Enzyme-Linked Immunosorbent Assay for Detection of Tylosin in Milk and Water Samples. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, [PMID:] [10.1016/S1872-2040(18)61106-5] |
| 12. Xuejun Cui, Rongguo Li, Xiaofei Liu, Jingfeng Wang, Xueqi Leng, Xiaolei Song, Qianqian Pei, Yu Wang, Su Liu, Jiadong Huang. (2017) Low-background and visual detection of antibiotic based on target-activated colorimetric split peroxidase DNAzyme coupled with dual nicking enzyme signal amplification. ANALYTICA CHIMICA ACTA, [PMID:29149989] [10.1016/j.aca.2017.10.009] |
| 13. Wei-Chuang Kong, Chen-Chen Li, Ai-Hong Zhang, Xin-Long Li, Qian-Rui Gong, Bing-Tan Jin, Xiao-Juan Jia, Xu-Ying Liu, Yan-Fei Kang. (2024) A colorimetric-aptamer-based assay for the determination of enrofloxacin through triggering the aggregation of gold nanoparticles. Analytical Methods, [PMID:39311407] [10.1039/D4AY01259C] |
| 14. Quanliang Li, Xin Wang, Xiyu Wang, Xiaomeng Wang, Dengyi Ye, Ping Chen, Dayong Ren. (2024) Hypersensitive colorimetric assay based on microbial inhibition for the detection of multiple antibiotics. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, [PMID:] [10.1016/j.jfca.2024.106579] |
| 15. Zhiang Hou, Huachun Lan, Xiaoqiang An, Ruijuan Liu, Lan Yang, Lie Liu, Huijuan Liu, Jiuhui Qu. (2024) Nitrogen-doped hierarchical porous carbon with enhanced interfacial affinity for the efficient adsorption of antibiotic micropollutants from water. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.155055] |
| 16. Xiaoxiang Cheng, Zhe Xu, Xinsheng Luo, Yi Chai, Jiajian Xing, Xinyu Zhang, Jingtao Xu. (2025) Self-limiting interfacial synthesis of inorganic thin films for high-performance organic solvent nanofiltration in pharmaceutical applications. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2025.134261] |
| 17. Tingjian Yang, Guoqing Chen, Chaoqun Ma, Lei Li, Taiqun Yang, Hui Gao, Chun Zhu, Anqi Hu, Wang Liu, Xingyi Guo, Wenhui Yang, Yuebin Yu, Yali Qian. (2025) Enrofloxacin-based fluorescence probe for rapid, sensitive, and low-cost detection of tylosin in milk. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.114459] |
| 18. Yi Zhang, Zhaoju Wu, Haizhu Shi, Yang Xie, Ming-Yu Wu, Chungu Zhang, Shun Feng. (2022) Copper mediated molecularly imprinted polymers for fast recognizing tylosin. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:35219066] [10.1016/j.jpba.2022.114674] |
| 19. Wei-Chuang Kong, Chen-Chen Li, Jun-Tao Niu, Xu-Ying Liu, Dong Wei, Yan-Fei Kang. (2025) A label-free aptasensor based on a fluorescent probe containing styrylbenzothiazole for detection of enrofloxacin. Analytical Methods, [PMID:40211802] [10.1039/D4AY02265C] |
| 20. Wenxiao Liu, Guohao Chen, Yue Li, Hongpo Dong. (2025) Development of a whole-cell biosensor for the detection of low concentrations of tetracycline. Journal of Environmental Sciences, [PMID:41177646] [10.1016/j.jes.2025.06.018] |
| 21. Jun Dong, Yuanjun Tang, Jiayin Ma, Peikun Jiang, Yinxiu Liu, Ruohui Lu, Yin Li, Shuqi Li, Yangqing Hu, Fei Wang. (2025) One-step synthesis of hierarchical porous Fe-supported biochar for rapid and efficient removal of antibiotics from water. Environmental Technology & Innovation, [PMID:] [10.1016/j.eti.2025.104699] |
| 22. Yongqing Liu, Huangwei Song, Muchen Zhang, Junyao Jiang, Yan Zhang, Jian Xu, Xi Xia, Shangshang Qin, Jianzhong Shen, Yang Wang. (2025) β,β-Dimethylacrylalkannin Restores Colistin Efficacy Against mcr- and TCS-Mediated Resistant Gram-Negative Bacteria via Membrane Disturbance. Antibiotics-Basel, 15 (1): [PMID:41594041] [10.3390/antibiotics15010003] |
| 23. Qiaonan Wang, Mingyao Yu, Han Dong, Jingjing Duan, Yanxia Ding, Jinxiao Wang, Yujie Guo, Yaqian Huang, Tao Zhang, Xiaoxing Dong, Fengzhi Piao, Zhixin Guo. (2026) Abscisic acid confers antibiotic stress tolerance in cucumber by alleviating antibiotic phytotoxicity and decreasing the levels of antibiotic and antibiotic resistance genes. JOURNAL OF HAZARDOUS MATERIALS, [PMID:41506203] [10.1016/j.jhazmat.2026.141060] |
| 24. Guomin Li, Zhuoyang Li, Liqiu Zhang, Pinliang Lai, Bing Wang. (2026) Universality of Tm-Doped g─C3N4 for Photocatalytic Activation of Persulfate in Organic Pollutant Degradation. ChemistrySelect, 11 (11): (e07294). [PMID:] [10.1002/slct.202507294] |