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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
USP7-IN-9 is a highly potent ubiquitin-specific protease 7 (USP7) inhibitor with an IC 50 value of 40.8 nM. USP7-IN-9 can induce apoptosis and arrest cell progression at G0/G1 and S phases in RS4; 11 cells. USP7-IN-9 reduces the protein levels of oncoprot
Appearance:Solid
IC50& Target:IC 50 : 40.8 nM (USP7)
In Vitro:USP7-IN-9 (compound L55) (0-50 μM; 3 or 6 days) exhibits inhibitory activity against cancer cells. USP7-IN-9 (1 μM; 0-72 hours) reduces the proportions of G2/M cells, and does not change the proportions of G0/G1 and S cells. USP7-IN-9 (0.1-1 μM;
Biological Activity:USP7-IN-9 is a highly potent ubiquitin-specific protease 7 (USP7) inhibitor with an IC 50 value of 40.8 nM. USP7-IN-9 can induce apoptosis and arrest cell progression at G0/G1 and S phases in RS4; 11 cells. USP7-IN-9 reduces the protein levels of oncoprot
| Canonical Smiles | OC1(CN(C=NC2=C(C3=CC=C(C[NH3+])C=C3)N(C)N=C24)C4=O)CC[NH+](CC5=CC=C(C(OC)=O)C=C5Cl)CC1.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F |
|---|---|
| Molecular Weight | 779.08 |
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